Clinical trials: Mortality in Intensive Care Units
ARDS, Human, Respiratory Failure
Driving Pressure and Mortality: in the Pediatric Intensive Care Unit (PICU)
Respiratory failure is one of the most common causes of both hospitalization and mortality in patients in the pediatric intensive care unit (PICU).
- Trial name
- NCT04419376
- Testing
- driving pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Mortality Prediction
28-day Mortality Prediction for Critically Ill Patients in the Intensive Care Unit: Physician-nurse vs. Score
There are several scores for predicting mortality within 28 days in the intensive care unit, including APACHE 2, MPM 2 and MODS.
- Trial name
- NCT06665529
- Testing
- 28-day mortality prediction by ICU staff and mortality scores
- Where
- Israel
- Sponsor
- Meir Medical Center
Thorax Traumas
The Investigation of Predicting Mortality and Morbidity in Patients Admitted to Intensive Care Unit With Thoracic Trauma Using Selected Biomarkers and Parameters
This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients.
- Trial name
- NCT06930222
- Testing
- blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Suleyman Demirel University
Fungal Invasive Disease
Predictive Factors of Mortality in Invasive Fungal Disease in Post-surgical Critical Care Unit
Invasive fungal disease in the critically ill patient is a serious complication that increases hospitalization times, morbidity and mortality, and healthcare costs.
- Trial name
- FPR-IIS (NCT04484376)
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital Universitario La Fe
Hyperdynamic, Left Ventricular Ejection Fraction
Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock
The study aimed to evaluate the cause and prognosis of hyperdynamic left ventricular ejection fraction in critically ill patients with sepsis.
- Conditions
- Hyperdynamic, Left Ventricular Ejection Fraction, Mortality, Intensive Care Unit
- Trial name
- NCT06993948
- Testing
- Transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Ain Shams University
Critical Illness, Intensive Care (ICU) Myopathy
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
An increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, Muscle Wasting, Loss of Physical Function
- Trial name
- EAT-ICU (NCT01372176)
- Testing
- Early Goal-Directed Nutrition, ASPEN-guidelines
- Where
- Denmark
- Volunteers
- 203 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Emphysematous Pyelonephritis
Factors Associated To Intensive Care Admission And Mortality In Patients With Emphysematous Pyelonephritis
Emphysematous pyelonephritis is a lifethreatening necrotizing infection of the kidney characterized by accumulation of gas in the renal parenchyma and within the surrounding tissues.
- Trial name
- NCT04326517
- Testing
- Nephrectomy
- Where
- Mexico
- Volunteers
- 65 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Critically Ill, Enterobacteriaceae Infections
Infections and Colonization With the Third Group of Enterobacteriaceae in the Intensive Care Unit
There is a lack of data whether colonization and infection with Enterobacteriaceae of the third group (EB3) affect the outcomes for ICU patients.
- Conditions
- Critically Ill, Enterobacteriaceae Infections, Antibiotic Resistant Infection
- Trial name
- EB3REA (NCT04528043)
- Where
- France
- Volunteers
- 179 people
- Sponsor
- Central Hospital, Nancy, France
Sepsis, Septic Shock
Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey
The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of sepsis in adult patients admitted to Intensive Care Units (ICUs) in…
- Conditions
- Sepsis, Septic Shock, Critical Illness, Organ Dysfunction
- Trial name
- TURK-SOFA2 (NCT07300306)
- Where
- Turkey (Türkiye)
- Volunteers
- 3,379 people
- Sponsor
- Marmara University
Intensive Care Unit, Mortality
Analysis of the Evolution of Mortality in an Intensive Care Unit
The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical…
- Conditions
- Intensive Care Unit, Mortality, Epidemiology, Respiration, Artificial
- Trial name
- NCT05261607
- Where
- Spain
- Volunteers
- 27,463 people
- Sponsor
- Hospital Universitario Getafe
Crush Syndrome, Rhabdomyolysis
Inflammation Indıces and Mortality in Adult Crush Syndrome
This single-center, retrospective observational cohort study evaluated the prognostic value of complete blood count-derived inflammatory indices - the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR)…
- Conditions
- Crush Syndrome, Rhabdomyolysis, Systemic Inflammatory Response, Critical Illness
- Trial name
- NCT07433127
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people
- Sponsor
- Ataturk University
Sepsis, Septic Shock
Adjunctive Fludrocortisone in Septic Shock
Sepsis is a life-threatening condition caused by the body's dysregulated response to an infection. While corticosteroids are known to help stabilize blood pressure in septic shock, their ability to reduce mortality is still…
- Conditions
- Sepsis, Septic Shock, Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis and Septic Shock
- Trial name
- AFLUDROS-1 (NCT07451886)
- Testing
- Fludrocortisone 100 mcg daily
- Where
- 5 sites in Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Inpatient Hospitalization, Intensive Care Unit Admission, Inpatient Mortality, Sepsis and Septic Shock
Linking Novel Diagnostics With Data-Driven Clinical Decision Support in the Emergency Department
The primary objective of this study is to validate the use of an electronic clinical decision support (CDS) tool, TriageGO with Monocyte Distribution Width (TriageGO-MDW), in the emergency department (ED).
- Trial name
- NCT05335135
- Testing
- TriageGO-MDW Clinical Decision Support, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Stocastic, LLC
COVID, Severe Acute Respiratory Syndrome
Obesity and Mortality of Critically Ill Patients With COVID-19
Disproportionate impact of COVID-19 in patients with obesity is now well established. Obesity is associated with severe forms of COVID-19 and may be a risk factor of intensive care unit (ICU) admission.
- Conditions
- COVID, Severe Acute Respiratory Syndrome, Obesity, Comorbidities and Coexisting Conditions
- Trial name
- COV-OB-ICU (NCT04425213)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Critical Illness, Postoperative Complications
General Surgery Patients at the Intensive Care Unit
Introduction: high-risk surgical patients in the intensive care unit (ICU) are a unique population that has yet to be carefully monitored.
- Trial name
- TraViII (NCT06731296)
- Testing
- Presence of a risk factor
- Where
- 2 sites in Colombia
- Volunteers
- 1,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Sepsis, Shock
Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients
The lack of subcutaneous partial pressure of oxygen (PO2) rise in response to high fraction of inspired oxygen (FiO2), called the "oxygen challenge test (OCT)", was associated with higher morbidity and mortality in human…
- Trial name
- ICUPtO2OCT (NCT01174966)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Localized Infection, Sepsis
The Procalcitonin and Survival Study
This is a randomised, single blinded, multicentre trial to evaluate whether daily procalcitonin (PCT) measurements and immediate diagnostic and therapeutic responses to abnormal values and day-to-day changes can reduce the…
- Conditions
- Localized Infection, Sepsis, Multiple Organ Failure
- Trial name
- PASS (NCT00271752)
- Testing
- Earlier therapeutic changes regarding infection
- Where
- 9 sites in Denmark
- Volunteers
- 1,200 people
- Sponsor
- Danish Procalcitonin Study Group
Traumatic Brain Injury (TBI) Patients, Intracranial Pressure
Role of Non-Selective Beta-Adrenergic Blocker in Severe TBI
The role of nonselective beta adrenergic blocker as antistress agent in severe traumatic brain injury
- Conditions
- Traumatic Brain Injury (TBI) Patients, Intracranial Pressure, Intensive Care Unit, Mortality
- Trial name
- NCT06870370
- Testing
- propranolol, normal saline IV
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University