Clinical trials: Mother
Pregnancy
Retinal Vascular Changes During Pregnancy
The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy.
- Trial name
- NCT06311617
- Testing
- Optical coherence tomography
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Influenza
Maternal Flu Vaccine Trial in Bamako, Mali
The Center for Vaccine Development - Mali is interested in learning if vaccinating a pregnant woman against influenza will protect her infant against this disease.
- Trial name
- NCT01430689
- Testing
- Inactivated Influenza Vaccine Trivalent Types A and B, Meningococcal Polysaccharide-Diphtheria Toxoid Conjugate Vaccine
- Where
- Mali
- Volunteers
- 4,193 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
18 Years and Over, Newborn Health
Multıdımensıonal Effects Of Delayed Cord Clampıng and Mılkıng on Placental Processes
This study was conducted to evaluate the effects of delayed cord clamping and milking the umbilical cord of term babies after 90 seconds during vaginal birth on the newborn and the mother and to determine whether it is a suitable…
- Conditions
- 18 Years and Over, Newborn Health, 37 or More Completed Weeks of Gestation
- Trial name
- DCC&MILKHEM P (NCT06865391)
- Testing
- Delayed cord clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
The objective of this study is to follow the treatment options offered to pregnant women diagnosed with cancer and study the impact that their treatment or delay of treatment has on their own health and that of their children.
- Trial name
- CANCRPREGREG (NCT02749474)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers
The primary objective of this study is to evaluate the impact of treating opioid use disorder (OUD) in pregnant women with extended-release buprenorphine (BUP-XR), compared to sublingual buprenorphine (BUP-SL), on mother and…
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs (NCT03918850)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- T. John Winhusen, PhD
Microbial Colonization, Antibiotic Side Effect
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome.
- Conditions
- Microbial Colonization, Antibiotic Side Effect, Cesarean Section Complications
- Trial name
- CSBabyBiome (NCT06030713)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Perinatal Mortality
Low-dose High-frequency Training of Facility Health Care Providers in Mali
This 3-arm cluster randomized trial (C-RCT) has the following objectives: Primary Aim To evaluate the effectiveness of an on-site case-based focused low-dose high-frequency training strategy in a primary health care facility…
- Trial name
- NCT03656237
- Testing
- Usual Training, Audits + LDHF Training
- Where
- Mali
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Post Partum Hemorrhage, Asphyxia; Fetal
Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal
Postpartum hemorrhage and birth asphyxia are the leading causes of maternal and neonatal mortalities worldwide. Prevention and adequate treatment are, therefore crucial.
- Conditions
- Post Partum Hemorrhage, Asphyxia; Fetal, Maternal-Fetal Relations
- Trial name
- SLAB (NCT06577922)
- Testing
- Establishment of a simulation lab and provision of simulation based trainings
- Where
- Nepal
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- One Heart Worldwide
Breastfeeding
The Effect of Training and Follow-up Given According to the Health Promotion Model on Relactation Success
The process of restarting or increasing lactation in a mother who wants to breastfeed her baby again after the termination of breastfeeding or decrease in lactation is called relactation.
- Trial name
- NCT05697302
- Testing
- Education, Follow-up, Referral to Lactation and Relactation Polyclinic
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Overweight or Obese
Weight Management in Mothers and Adult Daughters
The purpose of this study is to develop, implement, and evaluate a behavioral weight management intervention with a communication training component for Mexican-American women. The study has three specific aims.
- Trial name
- NCT02787902
- Testing
- Communication, Standard
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pregnancy, Phenylketonuria
Educational, Social Support, and Nutritional Interventions and Their Cumulative Effect on Pregnancy Outcomes and Quality of Life in Teen and Adult Women With Phenylketonuria
The purpose of this project is to study the effectiveness of teaching teens and young women with Phenylketonuria (PKU) or Maple Syrup Urine Disease (MSUD) about their disease and nutrition related issues in a camp environment.
- Trial name
- NCT01659749
- Testing
- Metabolic camp
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Emory University
Neurodevelopment, Child Growth
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe).
- Trial name
- BONDS (NCT07430826)
- Testing
- Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Type 1 Diabetes
T1D Risk Assessment in Kids With Relatives
The purpose of this study is to determine whether early immunological markers (activation of autoreactive T lymphocytes) precede and are predictive of the appearance of autoantibodies in children born from type 1 diabetic parents.
- Trial name
- TRAKR (NCT02184676)
- Testing
- Analysis of early immune modifications, Collection of clinical and socio-demographic data
- Where
- France
- Volunteers
- 512 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breastfeeding, Breastfeeding Education
Effectiveness of Breastfeeding Education Using a Lactation Simulation Model Among Nursing Students: A Randomized Controlled Trial
Breastfeeding education provided by nurses is an important determinant of breastfeeding success and maternal breastfeeding self-efficacy.
- Conditions
- Breastfeeding, Breastfeeding Education, Nursing Education
- Trial name
- LSM-BE (NCT07720076)
- Testing
- Lactation Simulation Model-Based Breastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Condition 1 - Educational Condition (Educational Book Group), Condition 2 - Non-educational Condition (Non-educational Book Group)
Using Baby Books to Promote Maternal and Child Health
The Baby Books Project tests whether embedding educational information into baby books can improve the health and wellbeing of first-time mothers and their young children.
- Conditions
- Condition 1 - Educational Condition (Educational Book Group), Condition 2 - Non-educational Condition (Non-educational Book Group), Condition 3 - Control Condition (No-book Group)
- Trial name
- NCT02203617
- Testing
- Educational Content/Pediatric Anticipatory Guidance, Book provision
- Where
- 2 sites in United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Depression, Postpartum, Depression
Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
This study will test an intervention that aims to prevent postpartum depression by providing new mothers with information on and resources for dealing with the disorder.
- Trial name
- NCT00951717
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Obesity, Childhood
FACILITY: Feeding the fAmiLy: the Intergenerational approaCh to fIght obesiTY
The FACILITY STUDY is aimed at evaluating maternal and children social, cultural, economic and lifestyle-related risk factors for the development of childhood overweight, obesity and early adiposity rebound (EAR).
- Conditions
- Obesity, Obesity, Childhood, Obesity, Maternal, Overweight
- Trial name
- FACILITY (NCT06164340)
- Volunteers
- 269 people
- Sponsor
- Buzzi Children's Hospital
Paternal Postpartum Depression, Postpartum Anxiety
Feasibility and Acceptability of a Novel Digital Intervention For Perinatal Men Who Have Depression or Anxiety
Postpartum depression (PPD) occurs almost as often among men as it does among women. However, while there have been multiple programs designed to prevent maternal PPD, few, if any, interventions exist that have been created…
- Trial name
- TIP-PLUS (NCT07742566)
- Testing
- Together in Parenting
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Prematurity
Effect of Auditory and Tactile-kinesthetic Stimulation on Preterm Neonates
The study was conducted at a level II special care nursery of the Moi Teaching \& Referral Hospital, an academic hospital in the Western region of Kenya.
- Trial name
- NCT04287322
- Testing
- Tactile-kinesthetic stimulation, Recorded maternal voice
- Where
- Kenya
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Moi University
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