Clinical trials: Mothers
Pregnancy
Randomized Trial of Vitamin B12 in Pregnant Indian Women
This study is a randomized, double-blind trial among 300 pregnant Indian women in order to determine the effectiveness of vitamin B12 supplementation in improving maternal B12 status.
- Trial name
- B12 (NCT00641862)
- Testing
- Vitamin B12
- Where
- India
- Volunteers
- 366 people
- Sponsor
- Harvard School of Public Health (HSPH)
HIV, Tuberculosis
Sustainable East Africa Research in Community Health
The SEARCH study aims to test evidenced-based innovative community based interventions that lead to the elimination of HIV in rural communities in East Africa using a multi-disease approach.
- Conditions
- HIV, Tuberculosis, Hypertension, Diabetes
- Trial name
- SEARCH (NCT01864603)
- Testing
- Universal ART in a streamlined care model, Annual Community Health Campaigns, Targeted PrEP and Targeted testing interventions
- Where
- 3 sites in Kenya, Uganda
- Volunteers
- 150,395 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fetal Monitoring, Patient Comfort
Evaluation of the Effects of Different Positions Given During Antenatal Electro-Fetal Monitoring
The objective of this study was to assess the effects of different maternal positions during electronic fetal monitoring (EFM) on maternal and fetal health outcomes.
- Conditions
- Fetal Monitoring, Patient Comfort, Maternal Health
- Trial name
- NCT05863156
- Testing
- Right side lying position, Semi Fowler, left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Pregnancy
Maternal Fetal Device Performance Singleton
Maternal Fetal Monitoring devices assist the health care professional in acquiring, monitoring, and storing fetal and maternal physiologic data which supports the decision making for pregnant women and the overall fetal health…
- Trial name
- NCT06726343
- Testing
- Fetal Monitoring Device, Investigational Fetal Monitoring Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GE Healthcare
Opioid Use, Postpartum Disorder
Prevention of Persistent Opioid Use in Mothers
Our previous work has identified the group of women at risk for prolonged pain, opioid use and poor functional recovery after childbirth. The optimal intervention to mitigate this risk is unknown.
- Conditions
- Opioid Use, Postpartum Disorder, Chronic Pain Syndrome
- Trial name
- NCT03472521
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Stanford University
Respiratory Syncytial Virus
A Study to Learn About the Vaccine RSVpreF In Pregnant Participants With HIV and Their Infants
The purpose of the study is to learn about the safety and immune activity of the RSVpreF vaccine. It will be studied in infants born to mothers living with HIV.
- Trial name
- MORISOT (NCT06325657)
- Testing
- RSVpreF vaccine, Placebp
- Where
- 14 sites in South Africa
- Volunteers
- 681 people
- Sponsor
- Pfizer
Labor, Induced, Cervical Ripening
Prehospital Cervical Ripening Before Induction and the Maternal Experience
This is a randomized study evaluating the impact of pre-hospital cervical ripening with a transcervical Foley balloon before labor induction in full-term pregnancies on the length of inpatient labor induction and maternal…
- Trial name
- "PRIME" (NCT01641601)
- Testing
- Outpatient transcervical Foley balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Pregnancy, Postpartum Period
Sleep Disruption in New Mothers: An Intervention Trial
The purpose of this study is to test a behavioral intervention to minimize sleep disruption and fatigue in new mothers after the birth of their first infant.
- Conditions
- Pregnancy, Postpartum Period, Sleep Disturbance
- Trial name
- MOMS (NCT01321710)
- Testing
- Sleep hygiene, Dietary information, Acetaminophen
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of California, San Francisco
Postpartum Depression
Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression
Postpartum depression (PPD) is undertreated and the consequences of this are substantial for women and children. Studies show that infant cry/fuss and sleep behavior are associated with PPD, and that parenting interventions can…
- Trial name
- NCT01379781
- Testing
- Behavioral Intervention for PPD
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Maternal Depression, Child Behavior Problem
Attachment and Biobehavioral Catch-up and Depression Treatment
Maternal depression influences the development of children's behavior problems and vice versa; however most interventions singularly address maternal depression or children's behavior problems rather than both.
- Trial name
- ABC+D (NCT05096611)
- Testing
- Attachment and Biobehavioral Catch up, Attachment and Biobehavioral Catch up Plus Depression Treatment
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Maternal Obesity, Gestational Weight Gain
Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Obesity is a serious and increasing health problem in the Western World with about one third of all pregnant women in Denmark being overweight. Among these are more than 11% severe obese.
- Conditions
- Maternal Obesity, Gestational Weight Gain, Obstetric Complications
- Trial name
- LiP (NCT00530439)
- Testing
- Lifestyle intervention, Control, Physical activity, dietetic counselling
- Where
- Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Sleep, Pregnancy
Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth
Every day in Ghana, 47 babies are stillborn (SB) and 232 babies are born with low birth-weight (LBW) - many of whom will die in infancy or suffer lifelong consequences.
- Conditions
- Sleep, Pregnancy, Stillbirth, Infant, Low Birth Weight
- Trial name
- NCT02379728
- Testing
- PrenaBelt, Body Position Sensor
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Allan Kember
Pregnancy Complications, Obesity
Acute Exercise Effects in Obese Pregnancy
Obesity before and during pregnancy is associated with a higher risk for a number of obstetric and metabolic complications in women and their offspring.
- Conditions
- Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
- Trial name
- NCT03750695
- Testing
- Resistance exercise, Aerobic Exercise, Rest
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Maternal Behavior, Alcohol Drinking
Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes
South Africa (SA) has a long history of social and health disparities, resulting in the world's highest rate of fetal alcohol spectrum disorder (FASD; 111.1 per 1,000), where lifelong negative cognitive and physical effects…
- Conditions
- Maternal Behavior, Alcohol Drinking, Fetal Conditions
- Trial name
- MaRISA+ (NCT05747599)
- Testing
- Intervention with contingent incentives and text-based support
- Where
- South Africa
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RTI International
Neonatal Abstinence Syndrome
Fetal and Infant Effects of Maternal Buprenorphine Treatment
This research will track the longitudinal neurobehavioral development of the buprenorphine-exposed fetus across gestation through 1 month of age in an effort to determine the safety of this medication for use during gestation…
- Trial name
- NCT01561079
- Testing
- Buprenorphine
- Where
- 2 sites in United States
- Volunteers
- 127 people
- Sponsor
- Johns Hopkins University
Metastatic Breast Cancer, Parenting
Fathers and Mothers Invested in Lives of Their Youth (FAMILY) Study: A Pilot Intervention
This is a single-arm pilot study to evaluate the feasibility and acceptability of a novel psychosocial intervention to improve psychosocial outcomes for parents with advanced cancer and their co-parents.
- Trial name
- FAMILY (NCT04092816)
- Testing
- FAMILY Intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Maternal Behavior, Postpartum Depression
Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk
The goal of this educational clinical trial is to identify high-need women most at risk for poor outcomes following delivery, the problems they experience, and to create a system to improve quality of postpartum care for these…
- Trial name
- HOME (NCT06276647)
- Testing
- HOME
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Pennsylvania
Fetal Monitoring
A Clinical Study for Validating the Equivalence of Bloomlife MFM-Pro to Clinical Standard-of-care for Performing Antepartum Fetal Monitoring
Bloomlife MFM-Pro is a non-invasive, wireless, external monitoring system used to measure fetal heart rate and maternal heart rate on pregnant women with a singleton pregnancy, starting from 32 weeks of gestation.
- Trial name
- NST (NCT04915131)
- Testing
- Bloomlife MFM-Pro
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bloom Technologies
Parent-Child Relations, Maternal Behavior
A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity
Childhood adversity affects almost two-thirds of the US population, is a major risk factor for the leading causes of disease and increases US economic health burdens.
- Conditions
- Parent-Child Relations, Maternal Behavior, Infant Behavior
- Trial name
- NCT04818112
- Testing
- ATVV, Attention control
- Where
- 2 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Breast Milk Expression
Early Initiation of Milk Expression in Mothers of Very Low Birth Weight Infants
Compelling evidence exists that breast milk helps protect very premature infants from prematurity-specific morbidities. Unfortunately, mothers of premature infants often exhibit delayed lactogenesis stage II (when the milk "comes…
- Trial name
- NCT01892085
- Testing
- Early initiation, Intermediate expression, Late initiation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Florida