Clinical trials: Mothers
ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child
Triple P forADHD Children's Mothers, Education of Behavioral Problems, and Change in Mothers' Attitude
The goal of this clinical trial is to investigate whether the Triple P program will reduce behavioral problems for ADHD children, improve mothers' sense of competency, and improve their attitudes The main questions it aims to…
- Conditions
- ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child, ADHD - Attention Deficit Disorder With Hyperactivity, Healthy Adult Females
- Trial name
- (ADHD) (NCT07069621)
- Testing
- Triple p level parenting program
- Where
- Palestinian Territories
- Volunteers
- 67 people
- Sponsor
- Palestine Polytechnic University
Depression, Postpartum, Efficacy, Self
A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care
The purpose of this study is to assess the effectiveness of a parenting intervention+usual care compared to usual care on postpartum depression and other mental health and parenting outcomes, as well as the feasibility and…
- Conditions
- Depression, Postpartum, Efficacy, Self, Anxiety
- Trial name
- MInD (NCT04998721)
- Testing
- Promoting First Relationships-Brief, Perinatal Integrated Care
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Mental Disorders
Padres Efectivos (Parent Activation): Skills Latina Mothers Use to Get Healthcare for Their Children
The goal of this study is to develop an intervention to teach activation skills to Latino parents who bring children for mental health services.
- Trial name
- NCT02329431
- Testing
- activation curriculum, support group
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of North Carolina, Chapel Hill
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Anxiety, Depression
Efficacy of CES in New Mothers During the Post Partum Period
The birth of a child is a major life event that can be filled with excitement, anticipation and joy. However, the transition and adaptation to new demands, roles, responsibilities, and changes in relationships can be stressful…
- Conditions
- Anxiety, Depression, Insomnia, Sleep Quality
- Trial name
- NCT03210155
- Testing
- Alpha-Stim AID CES (Active Comparator)
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Christina Murphey, RN, PhD
Pain, Breastfeeding
The Effect of Neuraxial Analgesia on Maternal Breastfeeding
A previous randomized trial showed a possible negative association with labor neuraxial analgesia with high compared to low doses of fentanyl, and breastfeeding at 6 weeks postpartum.
- Trial name
- NCT01074190
- Testing
- Group 1, Group 2, Group 3
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Infections
Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to-Child Transmission
HIV-infected pregnant women who begin taking antiretroviral (ARV) medications in the late stages of pregnancy need an effective medication regimen to reduce the risk of transmitting HIV to their children.
- Trial name
- NCT01618305
- Testing
- Lamivudine/zidovudine, Efavirenz, Raltegravir
- Where
- 19 sites in United States, Argentina and 5 more
- Volunteers
- 408 people
- Sponsor
- Westat
Opioid Related Disorders, Pregnancy
RCT Comparing Methadone and Buprenorphine in Pregnant Women
Children born to women who abuse drugs have a high risk of being born with birth defects and developmental problems. Methadone is a drug that is commonly used for treating opioid dependence.
- Conditions
- Opioid Related Disorders, Pregnancy, Opioid Dependence
- Trial name
- NCT00271219
- Testing
- Methadone, Buprenorphine
- Where
- 8 sites in United States, Austria and 1 more
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins University
Maternal Death During Childbirth, Pregnancy Complications
Wireless Physiologic Monitoring in Postpartum Women
To estimate the clinical effectiveness of wireless physiologic monitoring of women in the first 24 hours after cesarean delivery at Mbarara Regional Referral Hospital
- Trial name
- WIMS (NCT04060667)
- Testing
- Wireless physiologic monitoring
- Where
- Uganda
- Volunteers
- 3,191 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pregnancy
Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Epidural techniques offer the advantage of being able to titrate the level, density, and duration of the blockade through the use of a catheter and are associated with relative maternal hemodynamic stability.
- Trial name
- matvent (NCT02339389)
- Testing
- Labor analgesia
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Brigham and Women's Hospital
Obesity
Pattern - Reach Aim 2
The purpose of this research study is to learn about different approaches to promoting healthy growth among infants, and understanding parents' likes and dislikes of an approach to reducing risk factors for obesity later in life.
- Trial name
- NCT04216264
- Testing
- Standard response, Targeted response
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Duke University
Obstetric Labour, Premature
Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies
The primary objective of this study is to assess the safety and outcomes of infants and children who were exposed to retosiban or comparator in utero in the Phase III spontaneous preterm labor (SPTL) treatment studies, to provide…
- Trial name
- ARIOS (NCT02292784)
- Testing
- Retosiban, Atosiban
- Where
- 26 sites in United States, Belgium and 9 more
- Volunteers
- 98 people
- Sponsor
- GlaxoSmithKline
Maternal Death, Maternal Morbidity
Improving Women's Health Through Coordinated Postpartum Planning
The purpose of the study is to design, implement, and evaluate a holistic postpartum women's health care system for women who have cardiovascular risk factors for severe maternal morbidity (SMM) including chronic hypertension…
- Trial name
- NCT05430815
- Testing
- Enhanced Postpartum Care System
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Emory University
Hiv
Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town (Formative Study)
The overarching goal of this proposal is to evaluate the feasibility and acceptability of integrating PrEP into antenatal and postnatal care, to describe the cascade in women initiating PrEP in this setting, and to evaluate the…
- Trial name
- PrEP-PP (NCT03826199)
- Testing
- TDF-FTC, Counselling on PrEP in antenatal and postnatal care
- Where
- South Africa
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postpartum Depression, Small for Gestational Age at Delivery
Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention
In the proposed study the investigators will develop an early prenatal preventive intervention targeting anxiety and conduct a randomized controlled trial in Pakistan to test its efficacy in reducing generalized anxiety disorder…
- Conditions
- Postpartum Depression, Small for Gestational Age at Delivery, Preterm Birth, Anxiety
- Trial name
- HMHB (NCT03880032)
- Testing
- Cognitive Behavioral Therapy Intervention for Anxiety
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Maternal Health, Mental Health
Caring for Providers to Improve Patient Experience Study Phase 2 in Migori County
The activities described in this proposal are aimed at addressing health care provider stress and unconscious bias to improve quality of maternal health care, particularly related to the person-centered dimensions of care-i.e.
- Conditions
- Maternal Health, Mental Health, Healthcare Provider, Adverse Outcomes
- Trial name
- CPIPE2 (NCT05019131)
- Testing
- Training, Peer support and mentorship, Leadership engagement
- Where
- Kenya
- Volunteers
- 83 people
- Sponsor
- University of California, San Francisco
Breastfeeding Duration
BOOST: Breastfeeding Onset and Onward With Support Tools
This behavioral intervention trial will test whether a standard care breastfeeding intervention from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) program plus monthly financial incentives…
- Trial name
- NCT03964454
- Testing
- WIC support + home-based individual support + Breastfeeding Incentives (SC+BFI), WIC support + home-based individual support (SC)
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Philadelphia College of Osteopathic Medicine
HIV Infections
NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are commonly included in anti-HIV drug regimens. However, HIV infected women who have previously taken the single dose NNRTI nevirapine (SD NVP) for the prevention of…
- Trial name
- OCTANE (NCT00089505)
- Testing
- Emtricitabine, Emtricitabine/Tenofovir disoproxil fumarate, Lopinavir/Ritonavir
- Where
- 11 sites in Botswana, Kenya and 5 more
- Volunteers
- 745 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Effect of Taxes and Subsides on Food Purchases in Mothers
Price Changes and Hypothetical Food Purchases in Adult Grocery Shoppers
The goal of the proposed study is to apply experimental economics in an online grocery store shopping model to examine the effects of pricing on hypothetical food purchases
- Trial name
- Grocery (NCT01619787)
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Immunization; Infection, Pregnancy Related
VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination
COVID-19 infection during pregnancy is associated with increased risk of pre-eclampsia, preterm birth and stillbirth. Pregnant people with COVID-19 have a higher rate of ICU admission and intubation than those who are not…
- Conditions
- Immunization; Infection, Pregnancy Related, COVID-19
- Trial name
- NCT05570630
- Testing
- VAX-MOM COVID-19 Intervention, Standard of Care
- Where
- United States
- Volunteers
- 6,911 people, healthy volunteers welcome
- Sponsor
- University of Rochester