Clinical trials: Mothers
Physical Inactivity
Free Time For Wellness Pilot Effectiveness Trial
Physical inactivity is pervasive and prevalent in the United States, particularly among women of low socioeconomic position, and women with children.
- Trial name
- FT4W (NCT06474715)
- Testing
- Arms
- Where
- 3 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infections
Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth
The purpose of this study is to determine which of 3 different anti-HIV drug regimens given to HIV infected pregnant women during and after their pregnancies is most effective in reducing the incidence of nevirapine (NVP)…
- Trial name
- NCT00109590
- Testing
- Didanosine, enteric-coated, Lopinavir/ritonavir, Nevirapine
- Where
- 7 sites in Thailand
- Volunteers
- 175 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pregnancy Complications, Cesarean Section Complications
An Evaluation of the Team Birth Project
The purpose of this study is to evaluate the feasibility of a pilot project to improve communication and teamwork and to increase vaginal delivery rates at hospital in the United States
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Maternal Complication of Pregnancy, Communication, Multidisciplinary
- Trial name
- NCT03529214
- Testing
- Exposed study site
- Where
- 4 sites in United States
- Volunteers
- 5,217 people
- Sponsor
- Harvard School of Public Health (HSPH)
HIV Infection, Tuberculosis
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV
Tuberculosis (TB) is highly endemic in sub-Saharan Africa. The increased burden of TB in settings with high prevalence of the Human Immunodeficiency Virus (HIV) is associated with high rates of transmission of Mycobacterium…
- Conditions
- HIV Infection, Tuberculosis, Pneumocystis Jiroveci Pneumonia
- Trial name
- NCT00080119
- Testing
- Isoniazid (INH), Trimethoprim/Sulfamethoxazole (TMP/SMX)
- Where
- 6 sites in Botswana, South Africa
- Volunteers
- 1,354 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Post Partum Depression
Improving Outcomes for Low-Income Mothers With Depression
This is a randomized comparative effectiveness trial to improve outcomes among pregnant and post-partum women with symptoms of depression.
- Trial name
- NCT03221556
- Testing
- Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- Boston Medical Center
Depression
Using the LENA System in Early Intervention - b
This project will determine whether an intervention to enhance communication between infants and toddlers with developmental disabilities and their depressed mothers can be integrated into federally-funded Early Intervention (EI)…
- Trial name
- NCT03480841
- Testing
- Language ENhancement Assessment/intervention system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breastfeeding
Home Based Peer Support Program for Mothers With Low Breastfeeding Self-efficacy
An online home-based breastfeeding peer support programme is proposed to support mothers who are giving birth to their first-born.
- Trial name
- BFPS (NCT04621266)
- Testing
- Online Home-based peer support
- Where
- 2 sites in Hong Kong
- Volunteers
- 442 people
- Sponsor
- The University of Hong Kong
Enteral Feeding
Studying the Influence of Exposure to Maternal Voice on Oral Feeding Volumes in Preterm Infants
Oral feeding is one of the primary functions of the neonatal brain. In preterm infant population, competency at oral feeding is one of the major milestones in preparation for discharge.
- Trial name
- NCT05181020
- Testing
- Maternal Voice Exposure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Connecticut Children's Medical Center
Blood Pressure
Postpartum ASA and NT-proBNP
This study is a double-blinded randomized-controlled trial in which patients will be randomized to 81 mg of aspirin or placebo to be continued for 6 weeks' postpartum.
- Trial name
- NCT05889468
- Testing
- Aspirin 81Mg Ec Tab
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Duke University
Lactation
Recombinant Human Prolactin for Lactation Induction
The purpose of the study is to assess the safety and determine the effects of the hormone prolactin on lactation (breast milk production).
- Trial name
- NCT00181623
- Testing
- Recombinant Human Prolactin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Infections, Cytomegalovirus, Cytomegalovirus Infections
Study of the Transmission of Cytomegalovirus (CMV) Infection From Mother to Foetus
This study is designed to evaluate maternal virological and immunological parameters to determine their ability to predict congenital cytomegalovirus (CMV) infection.
- Trial name
- NCT01251744
- Testing
- Blood sample, Cord blood sample, Saliva swab
- Where
- 9 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- GlaxoSmithKline
Postpartum Depression, Parenting
Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms
The purpose of this study is to determine whether a social media-based parenting program can improve responsive parenting among mothers with Postpartum depression (PPD) symptoms.
- Conditions
- Postpartum Depression, Parenting, Parent-Child Relations
- Trial name
- NCT04045132
- Testing
- Social Media-Based Parenting Program, MoodGym
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Children's Hospital of Philadelphia
Premature Birth
Group Antenatal Care: Effectiveness and Contextual Factors Linked to Implementation Success in Malawi
In this study, we test the effectiveness of an evidence-based model of group antenatal care by comparing it to individual (usual) antenatal care (Aim 1) across 7 antenatal clinics in Blantyre District, Malawi.
- Trial name
- NCT03673709
- Testing
- Antenatal Care
- Where
- 7 sites in Malawi
- Volunteers
- 1,887 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Pregnancy Related, Postpartum Sadness
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women
The postpartum period is a critical time for both maternal and child health, and more than half of all maternal deaths occur postpartum, from one day to one year after birth.
- Trial name
- NCT04475718
- Testing
- Fourth Trimester Mobile Tool
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA
A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta
The primary purpose is to assess whether there is transfer of Certolizumab Pegol (CZP) from pregnant women receiving treatment with Cimzia® across the placenta to infants by evaluating the concentration of CZP in the plasma of…
- Conditions
- Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA, Ankylosing Spondylitis, Crohn's Disease
- Trial name
- CRIB (NCT02019602)
- Testing
- Blood sampling from mother, Blood sampling from infant, Blood sampling from umbilical cord
- Where
- 8 sites in United States, France and 2 more
- Volunteers
- 37 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Development, Child
Snacks, Smiles and Taste Preferences
The research study is designed is to determine whether children's acceptance of low sugar snacks, most preferred level of sweet and salty taste, and dietary intake of added sugars changes after repeated exposure to snacks lower…
- Trial name
- NCT03631992
- Testing
- Low Sweet, Regular Sweet
- Where
- 2 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Temple University
Pregnancy Related
Hospital Waterbirth Trial to Measure Maternal and Neonatal Outcomes
This study aims to explore outcomes of waterbirth in comparison to conventional land birth for low-risk healthy women and neonates in a hospital setting in Milwaukee, WI.
- Trial name
- NCT05175599
- Testing
- Water Birth
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Adverse Reaction to Spinal Anesthetic, Maternal Care for Cervical Incompetence
Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
This study aims to determine whether or not spinal anesthesia with the local anesthetic drug, chloroprocaine, wears off faster than the local anesthetic drug, bupivacaine, and results in faster discharge from the post-anesthesia…
- Trial name
- NCT02862912
- Testing
- Chloroprocaine, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infection
IMPAACT 1077HS: Examining Benefits of HAART Continuation in Postpartum Women
This study was a randomized strategy trial conducted among women who received highly active antiretroviral therapy (HAART) during pregnancy for purposes of prevention of mother-to-child transmission (PMTCT) of HIV but did not…
- Trial name
- NCT00955968
- Testing
- Highly active antiretroviral therapy (HAART)
- Where
- 50 sites in United States, Argentina and 7 more
- Volunteers
- 1,653 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group