Clinical trials: Motility Disorder
Gastroesophageal Reflux, Chronic Obstructive Pulmonary Disease
COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI
The purpose of this study is to determine which COPD patients have GERD and if COPD patients with GERD treated with high dose lansoprazole for 1 year decreases the frequency of COPD exacerbations compared to the previous year…
- Trial name
- GERD/COPD (NCT00523367)
- Testing
- 24 hour pH testing
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
GERD Gastroesophageal Reflux Disease
The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease
This study compares mechanical sphincter augmentation (LINX Reflux Management System) to double-dose proton pump inhibitors (PPIs) for the management of reflux symptoms related to gastroesophageal reflux disease (GERD).
- Trial name
- CALIBER (NCT02505945)
- Testing
- Omeprazole, LINX Reflux Management System
- Where
- 21 sites in United States
- Volunteers
- 152 people
- Sponsor
- Torax Medical Incorporated
Laryngopharyngeal Reflux
Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin
It is postulated that the incompetence of the upper esophageal sphincter (UES) to restrict passage of esophageal refluxate is fundamental to the development of LPR.
- Trial name
- NCT02552966
- Testing
- UESAD
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Strabismus, Reflex, Oculocardiac
Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Oculocardiac reflex (OCR) is usually happening in pediatric strabismus surgery and observed just when the surgent pulls the ocular muscles.
- Conditions
- Strabismus, Reflex, Oculocardiac, Hydroxyzine, Bradycardia Sinus
- Trial name
- NCT03806270
- Testing
- Midazolam, Hydroxyzine Dihydrochloride
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Yeditepe University
Semaglutide-Induced Gastric Motility, Gastroparesis
Body Surface Gastric Mapping in Patients on Semaglutide
Glucagon-like receptor-1 agonists (GLP-1 RAs), such as Semaglutide (Ozempic), are a class of drugs used for glycemic control in diabetes, and for weight loss and management in obesity.
- Trial name
- NCT06401746
- Testing
- Gastric Alimetry
- Where
- Australia
- Volunteers
- 9 people
- Sponsor
- University of Western Sydney
Pediatric Obesity, NAFLD
Effect of Obesity on Proton Pump Inhibitors
This longitudinal study tests the hypothesis that obesity affects drug pharmacology of acid suppression medications in children.
- Conditions
- Pediatric Obesity, NAFLD, GERD
- Trial name
- LiverLabPPI (NCT04248335)
- Testing
- Lansoprazole, Pantoprazole, Midazolam
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City