Clinical trials: Motion Sickness
Amblyopia, Motion Sickness
Impact of Different Types of Virtual Reality Games on Motion Sickness and Ocular in Adults: A Pilot Study
The research project titled "The Impact of Immersive Virtual Reality Training on Adult: Motion Sickness, and Ocular Surface: A Pilot Study" aimed to evaluate the initial safety impact of head-mounted virtual reality (HMVR)…
- Conditions
- Amblyopia, Motion Sickness, Dry Eye
- Trial name
- NCT06354309
- Testing
- Virtual reality game
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
Motion Sickness
Nasal Gel for the Prevention and Treatment of Nausea Associated With Motion Sickness
Phase 3 clinical trial is a randomized, double-blind, placebo-controlled study to identify the safety, efficacy and pharmacokinetics of a repeated-dose regimen of DPI 386 nasal gel (intranasal scopolamine gel) for the prevention…
- Trial name
- NCT04184115
- Testing
- DPI-386 Nasal Gel
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Drug Mechanism, Metabolism Medication Toxicity
Pharmacology Space Kit (PSK) - Dried Blood Spot for Caffeine Pharmacokinetics Under Microgravity Conditions
The PSK study is preliminary to the study of drug metabolism in space flight conditions. The investigators propose to use simplified blood sampling methods that can be applied in microgravity.
- Conditions
- Drug Mechanism, Metabolism Medication Toxicity, Space Motion Sickness
- Trial name
- PSK (NCT06431984)
- Testing
- prick test
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Elderly People, Living Alone in a Residence With Care Giver
Comparative Study of QuietCare
The objective of the study is to examine the efficacy and safety of QuietCare in a randomized, open study in elderly subjects living in assisted/ independent living facilities for 6 months.
- Trial name
- NCT01839825
- Testing
- QuietCare
- Where
- Japan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- National Center for Geriatrics and Gerontology, Japan
Motion Sickness, Space, Motion Simulation
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
The primary specific aim of this Field Test aim is to evaluate the feasibility and efficacy of administering the intranasal scopolamine gel in operational field settings using both astronaut and ground-control subjects that are…
- Conditions
- Motion Sickness, Space, Motion Simulation, Parabolic Flight
- Trial name
- NCT05852730
- Testing
- DPI-386 Nasal Gel, Other (e.g., promethazine, meclizine)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Motion Sickness
Virtual Reality Sickness Questionnaire: Psychometrics in Stroke Patients
The aim of this study is to examine the effects of virtual reality on physiological factors (heart rate, blood pressure) in stroke patients and the psychometric properties of the Virtual Reality Sickness Questionnaire in…
- Trial name
- NCT07297862
- Testing
- Roller Coaster application
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Motion Sickness
Preliminary Evaluation of an Osteopathic Manipulative Treatment (OMT) to Prevent Motion Sickness Symptoms
Motion sickness directly impacts the readiness of the Army's aviation units. Severe motion sickness results in the dismissal of pilot and air crew candidates during initial training, while minor to moderate symptoms can be…
- Trial name
- NCT05611814
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- United States Army Aeromedical Research Laboratory
Sea Sickness
Motion Sickness on Astrolabe's Vessel
Sea sickness syndrome is present for 80% of persons on board when the boat rotation missions Astrolabe, sometimes there is a risk of very significant dehydration.
- Trial name
- SICKVEST (NCT02911402)
- Testing
- sea sickness questionnaires
- Where
- France
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Motion Sickness
DPI 386 Nasal Gel for the Prevention of Nausea Associated With Motion Sickness
Determine the efficacy, in terms of time to nausea (inclination to vomit), of DPI-386 Nasal Gel as compared to the current standard of care (TDS) and placebo nasal gel.
- Trial name
- NCT04219982
- Testing
- DPI-386 Nasal Gel, Transderm Scop®
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Motion Sickness
Effects of Transdermal Scopolamine on Occupational Performance
The purpose of this study is to determine the effects of Transdermal scopolamine vs. placebo on ship navigation performance under simulated heavy sea conditions.
- Trial name
- NCT00374478
- Testing
- Scopolamine
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Boston University
Motion Sickness
A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants.
In this comparative bioavailability and in vivo skin adhesion study, the impact of minor changes in qualitative composition of polyiso-Butylenes (PIB) from a different supplier and change of the manufacturing line of the micro…
- Trial name
- NCT02839135
- Testing
- Reformulated scopolamine patch, Marketed scopolamine patch
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Motion Sickness
The Prevention and Treatment of Nausea Associated With Motion Sickness
This single-site Phase 3 clinical trial is a randomized, double-blind, placebo-controlled study to identify the safety and efficacy of a repeated-dose regimen of DPI 386 nasal gel (intranasal scopolamine gel) for the prevention…
- Trial name
- NCT03986905
- Testing
- Scopolamine Nasal Gel
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Motion Sickness, Seasickness
Galvanic Vestibular Stimulation as a Novel Treatment for Seasickness
subjects with severe seasickness, who failed to habituate to sea conditions after at least six month of active sailing, were enrolled to the single-blind randomized control study.
- Conditions
- Motion Sickness, Seasickness, Habituation, Vestibular Time Constant
- Trial name
- NCT05004818
- Testing
- GVS stimulation coupled with inverse phase rotatory chair stimulation at sinusoidal harmonic acceleration protocol
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Motion Sickness
Levo Phencynonate Hydrochloride for the Prevention of Seasickness
A double-blind, randomized, placebo controlled, multicenter, dose-finding phaseⅡclinical superiority study.
- Trial name
- NCT02241629
- Testing
- levo phencynonate hydrochloride
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sihuan Pharmaceutical Holdings Group Ltd.
Motion Sickness
Efficacy and Safety of DPI-386 Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion
This is a Phase 3, randomized, double-blind, placebo-controlled study evaluating DPI-386 Nasal Gel versus placebo. Approximately 500 subjects will be randomized 1:1 (250 DPI 386 Nasal Gel/250 matching Placebo Nasal Gel) are…
- Trial name
- NCT05548270
- Testing
- DPI-386 Nasal Gel
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Motion Sickness, Space, Visually Induced Motion Sickness
Virtual Reality in the Rehabilitation of Visually Induced Motion Sickness
In recent years, rapidly advancing virtual reality (VR) technology has been widely used in many fields, from education to health and from entertainment to therapeutic applications, by creating interactive and highly immersive…
- Conditions
- Motion Sickness, Space, Visually Induced Motion Sickness, Vestibular Rehabilitation in MS
- Trial name
- VIMS (NCT07318142)
- Testing
- The effects of virtual reality exposure were assessed using posturography.
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Chronic Nausea
Vagal Auricular Stimulation for Motion Sickness
This study aims to understand the mechanisms underlying nausea response in the brain stem, and the effect of vagal nerve stimulation on nausea.
- Trial name
- VAMOS (NCT07873164)
- Testing
- UROStim
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Motion Sickness
Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray
Part 1, the pharmacokinetic (PK) phase, will expand upon the pilot study conducted at Naval Medical Research Laboratory (NAMRL) and has the goal of determining bioavailability and time to Cmax in a larger representative sample.
- Trial name
- NCT02155309
- Testing
- Scopolamine
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Motion Sickness
Three-Axis Wearable Adaptive Vestibular Stimulator
The purpose of this study is to improve current galvanic vestibular stimulation (GVS) technology to ease the motion sickness often associated with virtual reality (VR) simulation.
- Trial name
- NCT06106256
- Testing
- Galvanic Vestibular Stimulation (GVS), Flight simulations in virtual reality (VR), 3-DOF Bertec Portable Essential's dual-balance force plate system
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dizziness, Vertigo
Sensory Training for Visual Motion Sickness
This is a preliminary study to determine the reliability and validity of new tests of orientation and balance, as well as to test the effects of a new treatment for visually induced dizziness.
- Conditions
- Dizziness, Vertigo, Motion Sickness
- Trial name
- NCT04420949
- Testing
- Sensory re-weighting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison