Clinical trials: Motor Activities
Obesity
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity adversely affects myocardial (muscular heart tissue) metabolism, efficiency, and diastolic function. The objective of this study was to determine if weight loss could improve obesity-related myocardial metabolism and…
- Trial name
- NCT00572624
- Testing
- Diet, Gastric bypass surgery
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pulmonary Arterial Hypertension
Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.
The primary objective of this study is to evaluate the effect of selexipag on the physical activity of patients with pulmonary arterial hypertension (PAH) in their daily life, by using a wearable wrist device (actigraph).
- Trial name
- TRACE (NCT03078907)
- Testing
- Selexipag
- Where
- 39 sites in United States, Austria and 8 more
- Volunteers
- 108 people
- Sponsor
- Actelion
Type 1 Diabetes
Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes
This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes…
- Trial name
- Activate (NCT05319600)
- Testing
- Diabetes behavior change skills training, Physical activity promotion program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Motor Activity
Modulation of Motor Learning Via tDCS in a Dexterous Video Game Task
The purpose of this study is to determine whether "transcranial direct current stimulation" (tDCS) is effective in enhancing learning of complex motor tasks of precision and accuracy that require the simultaneous coordination of…
- Trial name
- NCT07202702
- Testing
- tDCS
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cardiovascular Diseases
Exercise, Brain, and Cardiovascular Health
eBACH is a randomized intervention to determine the effects of aerobic exercise on brain structure and function, as well as to determine how exercise-induced training effects relate to cardiovascular function via related brain…
- Trial name
- eBACH (NCT03841669)
- Testing
- Aerobic Exercise Group, Physical Activity & Health Information Group
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking
Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)
This project proposes to evaluate the feasibility, acceptability, and efficacy of a mobile intervention to target smoking-cessation and increase physical activity among low-income persons.
- Trial name
- NCT02873754
- Testing
- Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Trauma, Brain, Brain Injuries
Intervention to Change Attributions That Are Negative (ICAN)
ICAN is the first treatment to target hostile attributions after TBI, making it a novel anger/ aggression management approach in this population. This is a randomized waitlist control trial.
- Conditions
- Trauma, Brain, Brain Injuries, Traumatic Brain Injury, Brain Injuries, Traumatic
- Trial name
- ICAN (NCT03648476)
- Testing
- ICAN
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Indiana University
Agitation in Dementia, Including Alzheimer's Disease
ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease
This is a randomized, double-blind, placebo-controlled study comparing the efficacy and safety of ITI-007 versus placebo administered orally once daily in the treatment of agitation in patients with dementia, including…
- Trial name
- NCT02817906
- Testing
- ITI-007
- Where
- 26 sites in United States
- Volunteers
- 177 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Motor Activity, Health Behavior
Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes
This study plans to learn more about physical activity and physical function in sedentary older adults with type 2 diabetes.
- Conditions
- Motor Activity, Health Behavior, Diabetes Mellitus, Type 2
- Trial name
- NCT02473926
- Testing
- Physical Activity, Questionnaires
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Colorado, Denver
Multiple Sclerosis
Aspirin for Exercise in Multiple Sclerosis (ASPIRE)
This study investigates the use of aspirin as an exercise pre-treatment to reduce overheating and exhaustion, which may potentially allow many more people with multiple sclerosis to participate in and benefit from exercise.
- Trial name
- ASPIRE (NCT03824938)
- Testing
- Aspirin 650mg Oral Capsule, Acetaminophen Tablet 650mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Dietary Habits
Tanglewood Trail Walking Program in Rural Kentucky 2017
The Tanglewood Trail Walking Program is a well-established community health initiative that encourages community members to walk approximately 1 mile to the Whitesburg Farmers Market each Saturday.
- Trial name
- NCT03495648
- Testing
- walking group led by a community organizer
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Dawn Brewer
Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic
The Effectiveness of Regular Exercise on Improving Sleep in Older Adults
This study will evaluate the effect of regular aerobic exercise on improving sleep in older adults with moderate difficulty sleeping.
- Trial name
- RTC (NCT00149747)
- Testing
- Moderate-Intensity Aerobic Physical Activity, Health Education Class
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Childhood, Physical Activity
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers
Childhood obesity and metabolic risk are at record high levels in the US, and Latino children are at very high risk. This project will test an intervention called Fit 5 Kids, designed for Latino preschoolers to decrease their…
- Conditions
- Obesity, Childhood, Physical Activity, Nutrition
- Trial name
- Fit5Kids (NCT03575884)
- Testing
- Screen Time Reduction Curriculum
- Where
- 3 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Aging, Physical Activity
Smart Television and Exercise Promotion for Independent Living Facilities
Physical activity (PA) has physical, emotional, and cognitive benefits for seniors (e.g., increased strength and balance, reduced frailty, fewer falls, improved brain function, lower mortality risk), yet many seniors have limited…
- Trial name
- STEP4Life (NCT03001778)
- Testing
- Usability Testing
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement
Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
This phase II trial studies how well anamorelin hydrochloride, physical activity, and nutritional counseling work in decreasing cancer-related fatigue in patients with incurable solid tumors that have spread to other parts of the…
- Conditions
- Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement, Cancer Fatigue, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03035409
- Testing
- Anamorelin Hydrochloride, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- M.D. Anderson Cancer Center
Fibromyalgia
Pain Outcomes Comparing Yoga Versus Structured Exercise (POYSE) Trial
The Pain Outcomes comparing Yoga versus Structured Exercise (POYSE) Trial is a 2-arm parallel group, randomized clinical trial to compare the effectiveness of a yoga-based intervention (YOGA) with that of a structured exercise…
- Trial name
- POYSE (NCT01797263)
- Testing
- Yoga, Structured Exercise
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- VA Office of Research and Development
Sports Physical Therapy
Prospective Evaluation of the Impact on Patients' Quality of Life of a 12-Week Adapted Physical Activity Program (APA)
The objective of this study is to evaluate the effects of regular physical practice on fatigue, quality of life and kinesiophobia in patients treated at the ICO in Angers, regardless of the type of cancer and the type of…
- Trial name
- APA (NCT04675814)
- Testing
- Adapted Physical Activity (APA)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Institut Cancerologie de l'Ouest
Physical Disability
On the Move: Optimizing Participation in Group Exercise
Community-dwelling older adults fear loss of independence and nursing home placement more than death. Walking difficulty often leads to loss of independence.
- Trial name
- OTM-PCORI (NCT01986647)
- Testing
- On the Move exercise - exercise leader, Standard program - exercise leader, On the Move exercise - staff activity personnel
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer
A Single Arm Pilot Study to Refine a Novel Approach to Exercise Promotion Based on Affect-regulation
The purpose of this study is to refine the use of an affect-regulated exercise prescription for use with survivors of breast cancer.
- Trial name
- NCT04903249
- Testing
- Core Exercise Promotion Intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
The purpose of this study is to test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening in primary care, 2)…
- Trial name
- OA-PCP (NCT04533711)
- Testing
- OA-PCP Intervention, Attention Control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of North Carolina, Chapel Hill