Clinical trials: Motor Activity
Sedentary Time, Frailty
The Sedentary to Active Rising to Thrive (START) Trial
The goal of this behavioral clinical trial is to compare two different ways of becoming less sedentary and more active in 60 older adults at elevated risk of becoming frail.
- Trial name
- START (NCT06023680)
- Testing
- Continuous sedentary reduction intervention, Bouted sedentary reduction intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Physical Activity, Primary Care
A Pedometer-based Intervention With and Without Email Counselling in General Practice
A two-arm parallel randomised controlled trial comparing pedometer-based intervention with and without email counselling in a primary care setting.
- Conditions
- Physical Activity, Primary Care, General Practice
- Trial name
- NCT03135561
- Testing
- pedometer-plus-email, pedometer-only
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Health Behavior, Genetic Information
The DNA-Based Lifestyle Enhancement Trial
Despite the known cardiovascular benefits of regular physical activity and having a balanced diet, it has proven challenging to change health behaviours towards favourable lifestyles.
- Conditions
- Health Behavior, Genetic Information, Cardiovascular Risk Factor
- Trial name
- DNAble (NCT03583983)
- Testing
- Personalized Health Recommendations, Generic Health Recommendations
- Where
- Canada
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Major Depressive Disorder, Mood Disorders
Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability).
- Conditions
- Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)
- Trial name
- MoodCatcher (NCT07427966)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cocaine Induced Sympathoexciation and Vasoconstriction
Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine
The purpose of this study is to improve the scientific understanding of the cardiovascular actions of cocaine, in particular the ability of cocaine to increase blood pressure.
- Trial name
- NCT00338546
- Testing
- Cocaine hydrochloride, Dexmedetomidine, Microneurography
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Osteoarthritis
Chronic Muscle Disuse in the Elderly
The purpose of this study is to define the effects of chronic disuse on skeletal muscle structure and function in elderly individuals at the cellular and molecular level by examining elderly characterized by chronic muscle disuse…
- Trial name
- NCT01190046
- Testing
- Resistance exercise training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Healthy
Effects of Water-soluble Olive Extract Supplementation
Six weeks of supplementation of an olive extract will: Improve antioxidant status Reduce inflammation Reduce muscle damage Improve exercise performance Improve exercise recovery as compared to a placebo.
- Trial name
- NCT01113827
- Testing
- Olive Extract
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Insomnia, Cardiorespiratory Fitness
Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors
Insomnia is a highly prevalent sleep disorder worldwide, with an increasing incidence in athletes, older adults, university students, and individuals with metabolic syndrome.
- Conditions
- Insomnia, Cardiorespiratory Fitness, Metabolic Disease
- Trial name
- INSIGHTS (NCT06869486)
- Testing
- Exercise, Bioelectrical Impedance, Micronucleus Assay
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Smoking
Comparison of the Effects of Different Chest Techniques on University Students With Smoking Addiction
Smoking is a significant risk factor for heart, lung, and respiratory system diseases, and is particularly prevalent among young people and university students.
- Trial name
- NCT07488741
- Testing
- Chest PNF Techniques Group, Chest Mobility Exercises Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Behcet Syndrome
Assessment of Disease Activity in Behcet by Complete Blood Count
To determine platelet to lymphocyte ratio (PLR), lymphocytes to monocytes ratio (LMR), mean platelet volume (MPV) and neutrophile lymphocyte ratio (NLR), levels in Behçet's disease (BD) To investigate their correlation with…
- Trial name
- NCT03747354
- Testing
- blood samples
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obstructive Sleep Apnea
The Continuous Positive Airway Pressure Effect on Rho-associated Coiled-coil Containing Kinases Activity.
The ROCK (Rho-associated coiled-coil containing kinases) play a critical role in the pathogenesis of cardiovascular diseases and left ventricle hypertrophy (LVH).
- Trial name
- NCT05014529
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy Volunteer
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MRG-110 Following Intradermal Injection in Healthy Volunteers
MRG-110 is intended to promote the growth of new blood vessels by inhibiting a molecule called miR-92a. MRG-110 is being studied to determine if it can accelerate healing of wounds by improving blood flow into the wound area.
- Trial name
- NCT03603431
- Testing
- MRG-110
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- miRagen Therapeutics, Inc.
Healthy People Programs
Effects of 20-week Mat-Pilates & Dual-Task Training on Strength, Balance, Cognition, and Fall Risk in Older Adults
Our aims are to evaluate the impact of 20-week combined Pilates and dual-task exercises on physical fitness, balance, cognitive function, bone density in older adults.
- Trial name
- Pilates&ST (NCT07119762)
- Testing
- Pilates sections
- Where
- Portugal
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Developmental Disabilities
The Experiences of Parents Learning Physiotherapy Techniques for Their Child
The experiences of learning from paediatric physiotherapists were explored through unstructured interviews applying Colazzi's method to interpret the data.
- Trial name
- NCT02090946
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Dementia, Physical Activity
Co-design and Pilot Study in VR-based Physical Activity and Cognitive Training
Physical activity and reminiscence therapy alone have been studied with no clear effectiveness in Alzheimer's disease, but their combined intervention remains unknown.
- Conditions
- Dementia, Physical Activity, Reminiscence Therapy, Co-design
- Trial name
- NCT06982170
- Testing
- A physical activity and reminiscence therapy
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hong Kong University of Science and Technology
Cardiovascular Risk Factor, Prediabetes
Active You: A Novel Exercise Program for African Americans
Barriers to physical activity (PA) among African Americans (AAs) have been extensively studied, yet there is a paucity of innovative PA interventions designed to address them.
- Conditions
- Cardiovascular Risk Factor, Prediabetes, Overweight and Obesity, Sedentary Behavior
- Trial name
- NCT04280783
- Testing
- The Physical Activity for The Heart (PATH) intervention, Be Active Your Way Booklet
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoporosis
Effect of Bone on Vibration-Induced Muscle Electrical Activity
The aim of this study is to investigate effects of femur exposed to vibration on the rest muscle electrical activity of hip adductors in cases with postmenopausal osteoporosis.
- Trial name
- PMO-WBV-sEMG (NCT01367041)
- Testing
- vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Ventricular Function
The Effect of Exercise and Alagebrium on the Diastolic Function of the Heart
The purpose of this study is to determine whether an investigational drug (Alagebrium (generic: ALT-711), a type of medication referred to as an advanced glycaton end-product clever) can be combined with exercise training to…
- Trial name
- AGE (NCT01014572)
- Testing
- Aerobic Exercise Training, Alagebrium (generic: ALT-711), Tai Chi and/or Yoga Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Physical Activity
Acute Cycling on Executive Control
This study will examine whether 10-minute bouts of cycling at various intensities will impact executive functioning (i.e., cognitive ability) as assessed by the antisaccade (AS) task through a total of five visits.
- Trial name
- ACE (NCT03499977)
- Testing
- Sitting, Light-Intensity Cycling, Moderate-Intensity Cycling
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
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