Clinical trials: Motor Control Impairment
Physical Frailty, Mild Cognitive Impairment (MCI)
Effects of Music-with-Movement on Cognitive and Physical Performance of People With Potentially Reversible Cognitive Frailty: a Randomised Controlled Trial
This study aims to evaluate the effects of Music-with-Movement Simultaneous Cognitive-Motor Dual-Task Training (MM-SDTT) on cognitive and physical performance in older adults with cognitive frailty coexisting with mild cognitive…
- Conditions
- Physical Frailty, Mild Cognitive Impairment (MCI), Cognitive Frailty
- Trial name
- NCT06791720
- Testing
- music-based cognitive-motor dual-task training/exercise, Social Gatherings
- Where
- Hong Kong
- Volunteers
- 113 people
- Sponsor
- The Hong Kong Polytechnic University
Ischemic Stroke, Hemiplegia
Repetitive Transcranial Magnetic Stimulation for Motor Recovery After Ischemic Stroke (rTMS-MOTOR)
Ischemic stroke is a leading cause of long-term motor disability, frequently resulting in hemiplegia and limitations in daily activities and quality of life.
- Conditions
- Ischemic Stroke, Hemiplegia, Motor Function Impairment
- Trial name
- rTMS-MOTOR (NCT07369648)
- Testing
- Active repetitive transcranial magnetic stimulation, Conventional motor rehabilitation
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Hanoi Medical University
Randomised Controlled Trial, Major Neurocognitive Disorder
Exergaming in People With Major Neurocognitive Disorder
This randomized controlled trial explores the efficacy of an 8-week standing exergaming program in people with major neurocognitive disorder (MNCD) residing in long-term care facilities.
- Conditions
- Randomised Controlled Trial, Major Neurocognitive Disorder, Long-term Care Facility, Physical Activity
- Trial name
- NCT04436302
- Testing
- Exergame device
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Davy Vancampfort
Headache
Exercise and Manipulative Therapy for Older Persons With Headache
The presence of cervical musculoskeletal impairment is not specific to cervicogenic headache but other various frequent intermittent headache types (i.e. migraine and tension-type headache) in the elderly population.
- Trial name
- NCT01736774
- Testing
- Usual care intervention, Physiotherapy treatment
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Chiang Mai University
Cognition, Mood
Prevention of the Age-Related Cognitive Impairment by Exercise and Mental Activity - Berlin Bleibt Fit
The trial will evaluate the effects of frequent exercise and increased mental activity on the age-related impairment of cognitive function in elderly women.
- Trial name
- BBF (NCT00629174)
- Testing
- Exercise, Mental activity
- Where
- 2 sites in Germany
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Physical Activity, Cancer of the Prostate
Prostate Cancer Survivors and Exercise and Behavioral Counseling
This study will evaluate the feasibility of delivering a supervised physical activity program plus standard exercise counseling (SPA+EC) versus a supervised physical activity plus motivationally-enhanced behavioral counseling…
- Conditions
- Physical Activity, Cancer of the Prostate, Cognitive Impairment, Quality of Life
- Trial name
- BOOST (NCT03191968)
- Testing
- Supervised Physical Activity Plus Behavioral Counseling, Supervised Physical Activity Plus Exercise Counseling
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes
Walking Away: Structured Education Versus Written Information for Individuals With High Risk of Developing Type 2 Diabetes
Diabetes is a debilitating chronic disease reaching epidemic proportions. Lack of physical activity is a key factor driving this epidemic and it is therefore vital that workable methods of encouraging people to exercise and…
- Trial name
- NCT00941954
- Testing
- Structured Education, Written Information
- Where
- United Kingdom
- Volunteers
- 833 people
- Sponsor
- University Hospitals, Leicester
Amyotrophic Lateral Sclerosis, Parkinson Disease
A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria
The goal is to improve the fundamental knowledge about articulatory motor performance in people with Lou Gehrig's disease (also known as ALS) and Parkinson's disease (PD), in order to develop more sensitive assessments for…
- Trial name
- NCT03613038
- Testing
- Phonetic complexity effects on speech motor performance
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Stroke, Upper-limb Motor Impairment
Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments
This is a multicenter, randomized, controlled clinical study evaluating the safety and effectiveness of the Spatial StimelMD (SSMD) device for upper-limb neuromotor rehabilitation in adults with impairment following stroke or…
- Conditions
- Stroke, Upper-limb Motor Impairment, Hemiparesis, Spinal Cord Injury
- Trial name
- NCT07404761
- Testing
- Spatial StimelMD (SSMD), Functional Electrical Stimulation (FES)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Motion Informatics LTD
Stroke
Pilot Trial of Robotic Hand Therapy After Stroke
This pilot study will test whether the GRIP program-a soft robotic glove with virtual-reality training-can improve hand and arm function in adults undergoing inpatient rehabilitation after a recent stroke.
- Trial name
- NCT07706621
- Testing
- robotic-assisted hand therapy, Action-observation therapy & Education
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Multiple Sclerosis
Robot-assisted Gait Training in Multiple Sclerosis Subjects
Aims of the study: This is a randomized-controlled trial to test the effects of robot-assisted gait training on locomotor function and motor unit firing rate in multiple sclerosis subjects with severe gait impairments.
- Trial name
- NCT01435694
- Testing
- Lokomat (Hocoma, Switzerland), Conventional Therapy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Hospital of Ferrara
Stroke, Hemiplegia
Combined Mirror Therapy and Soft Robotic Glove for Hand Recovery After Stroke
Post-stroke hemiplegia frequently results in impaired upper limb function, which significantly affects independence and quality of life.
- Conditions
- Stroke, Hemiplegia, Upper Limb Motor Impairment
- Trial name
- MT-SRG (NCT07467915)
- Testing
- Conventional Rehabilitation, Mirror Therapy, Soft Robotic Glove
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- University of Baghdad
Parkinson Disease, Balance Impairment
Effects of Exercise With Visual Feedback in Parkinson's Disease
Patients with Parkinson's disease who apply to the Hasan Kalyoncu University Application and Research Center and meet the inclusion criteria will be included in the study.
- Conditions
- Parkinson Disease, Balance Impairment, Exercise Training, Postural Control
- Trial name
- NCT07322939
- Testing
- Control Group, Visual Feedback Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hasan Kalyoncu University
Chronic Stroke Patient, Motor Impairment
Multifocal Theta-Burst Stimulation to Enhance Upper Limb Motor Recovery After Stroke (INSPIRE)
Stroke is one of the leading causes of long-term disability worldwide. Many individuals who survive a stroke continue to experience weakness and reduced control of one arm, even months or years after the event.
- Conditions
- Chronic Stroke Patient, Motor Impairment, Neurorehabilitation, Theta Burst Stimulation
- Trial name
- INSPIRE (NCT07439367)
- Testing
- Active iTBS, Tablet-based upper limb training
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Low Back Pain
A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain
Recent research has shown that classifying patients with low back pain into treatment subgroups results in better improvements than treating all patients with low back pain the same.
- Trial name
- NCT02060617
- Testing
- Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Hendricks Regional Health
Mild Cognitive Impairment
Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI
Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria.
- Trial name
- NCT06935812
- Testing
- Bimanual Exercise, Finger Exercise, Virtual Reality
- Where
- Cyprus
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Stroke, Parkinson Disease
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
This randomized controlled pilot trial evaluates the usability and safety of PhiCube, a compact, portable, bilateral end-effector robotic device for upper limb rehabilitation, and its impact on motor and cognitive function.
- Conditions
- Stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Spinal Cord Injuries
- Trial name
- PhiCube-Adults (NCT07865260)
- Testing
- PhiCube, Conventional rehabilitation
- Where
- 4 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Scleroderma, Systemic, Scleroderma, Diffuse
Exercise With Scleroderma Functional Outcomes
The study aims to investigate the effects of an exercise program applied to patients with scleroderma on functional outcomes (hand and mouth functional results and quality of life).
- Conditions
- Scleroderma, Systemic, Scleroderma, Diffuse, Scleroderma, Limited, Hand Rheumatism
- Trial name
- NCT06425653
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Trakya University
Dementia, Mild Cognitive Impairment (MCI)
Combating Alzheimer's Through Sleep and Exercise
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
- Trial name
- CASE (NCT04855630)
- Testing
- Elemind Neuromodulation Headband, Exercise Routine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami