Clinical trials: Motor Disability
Stroke, Amyotrophic Lateral Sclerosis
Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational Rehabilitation
This interventional, multicenter, low-intervention clinical trial aims to evaluate the usability, feasibility, safety, and preliminary clinical impact of a robotic rehabilitation system designed for upper limb rehabilitation in…
- Conditions
- Stroke, Amyotrophic Lateral Sclerosis, PARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)
- Trial name
- ASULDAR (NCT07636538)
- Testing
- Auto-calibrating System for Upper Limb disability Assessment, neurological and occupational Rehabilitation, conventional therapy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Down Syndrome
Motor Intervention Whit the Intorus Tool on Children With Down Syndrome
The goal of this clinical trial is to test in people with down syndrome how does the INTORUS tool influence their psychomotor development.
- Trial name
- NCT05740046
- Testing
- INTORUS
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Extremadura
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Aggressive Behavior in Fragile X Syndome
Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome
The goal of this clinical trial is to learn if drug SRX246 works to treat irritability, agitation, aggression and self-injury (IAAS) behaviors in adult males with Fragile X Syndrome (FXS).
- Trial name
- NCT07328529
- Testing
- SRX246
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Azevan Pharmaceuticals
Stroke, Motor Disorders
Effectiveness of a Rehabilitation Exercise Plan at Home to Treat Post-stroke Patients in the Chronic Phase
Background: Stroke is the second leading cause of death worldwide and the primary medical cause of disability. It is estimated that 45% of affected individuals will continue to have moderate or severe functional disabilities…
- Conditions
- Stroke, Motor Disorders, Physical Disability
- Trial name
- NCT06392802
- Testing
- Rehabilitation treatment using Muvity
- Where
- 2 sites in Spain
- Volunteers
- 39 people
- Sponsor
- Universitat Politècnica de Catalunya
Down Syndrome
Blood Flow in Individuals With Down Syndrome
This study focuses on physiological explanations of difficulties with physical activity and exercise in individuals with Down syndrome, by non-invasively examining cardiac output and the regulation of blood flow to working…
- Trial name
- NCT03590665
- Testing
- Hand grip exercise and lower body negative pressure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Down Syndrome, Trisomy 21
Cognitive Orientation to Daily Occupational Performance and Conductive Education Approaches on Down Syndrome
This study will be conducted to investigate and compare the effects of Cognitive Orientation to Daily Occupational Performance (CO-OP) and Conductive Education (CE) on fine motor skills, activity, and participation limitations in…
- Trial name
- NCT03687619
- Testing
- CO-OP, Conductive Education
- Where
- Cyprus
- Volunteers
- 12 people
- Sponsor
- Eastern Mediterranean University
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Chronic Neck Pain
Eye-cervical Re-education and Motor Control Training Program in Chronic Neck Pain
The study was conducted to determine the comparative effects of an eye-cervical re-education and motor control training program on pain, range of motion and functional disability in chronic neck pain
- Trial name
- NCT07438548
- Testing
- Eye-cervical Re-education Program, Motor Control Training Program, Standardized Physiotherapy Treatment
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Congenital Heart Defects, Down Syndrome
Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD
Congenital heart diseases (CHD) are detected in 40-60% of individuals with Down syndrome (DS) and increase the risk of developmental delay in the presence of syndromes.
- Conditions
- Congenital Heart Defects, Down Syndrome, Gross Motor Development Delay
- Trial name
- NCT05191654
- Testing
- evaluation of cardiopulmonary parameters, gross motor development and hand grip strength
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Atılım University
Diagnosis and Follow up on Upper Extremity Interventions
Quantification of Kinematics and Muscle Activity Patterns of the Upper Extremities of Individuals With Motor Disabilities
The subjet is sitting on a chair and in front of him an adjustable (height) table with a glass of water. 17 passive reflective markers are placed on his upper extremities and torso.
- Trial name
- NCT02162342
- Testing
- Rehabilitative treatment
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Supranuclear Palsy, Progressive
Study of the Distractibility Syndrome in Patients With Progressive Supranuclear Palsy
The syndrome of distractibility is a behavioral disorder induced by a lesion or a dysfunction of the frontal lobe. This sign is frequent in patients with progressive supranuclear palsy (PSP), a neurodegenerative disorder with…
- Trial name
- NCT00139373
- Testing
- donepezil
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Williams Syndrome
Motor Deficits and Signal Conduction in Individuals With Williams Syndrome
The current study aims to validate basic research findings of abnormal conductivity and motor abilities from a mouse model in humans.
- Trial name
- NCT05430763
- Where
- Israel
- Sponsor
- Sheba Medical Center
Healthy Volunteers
Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities
This study will evaluate new assessment tools and equipment and new ways of using existing tools and equipment in the NIH Clinical Center s Rehabilitation Medicine Department in order to maximize patients function.
- Trial name
- NCT00747955
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Multiple Sclerosis
Functional Electrical Stimulation Cycling for Managing Mobility Disability in People with Multiple Sclerosis
Mobility impairment is one of the most common, poorly managed, and life altering consequences of MS. Current therapies for managing MS do not prevent the long-term accumulation of mobility impairment, highlighting the need for…
- Trial name
- NCT03949387
- Testing
- FES Cycling Exercise, Passive Leg Cycling
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Ottawa
Osteoarthritis, Hip, Osteoarthritis, Knee
Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)
The aim of this study is to determine, in the framework of a randomized controlled clinical trial, whether Tai Chi can affect measurable improvements in self-reported outcomes such as pain, physical function and psychological…
- Trial name
- NCT00123994
- Testing
- Tai Chi classes, Hydrotherapy classes
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- St George Hospital, Australia
Young Children With Motor Disabilities
Compare the Effectiveness of Modified Toy Cars Training With Various Intensity of Postural Combinations
The three purposes of this study are: 1) to determine the feasibility of applying two types of postural combinations for the ride-on car (ROC) use; 2) to compare the effectiveness of ROC training with various intensity of…
- Trial name
- NCT03707405
- Testing
- Ride-On Cars Training with Different Postures
- Where
- 2 sites in Taiwan
- Volunteers
- 19 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebrovascular Disorders
Treatment for Movement Problems in Elderly Stroke Patients
After a stroke, many patients are left with an impaired arm. Restricting the use of the good arm may improve the use of the bad arm.
- Trial name
- NCT00059696
- Testing
- Constraint-Induced Movement Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Tetraplegia
NeuroCognitive Communicator: Safety Study
Individuals suffering from tetraplegia as a result of cervical spinal cord injury, brainstem stroke, or amyotrophic lateral sclerosis (ALS) cannot independently perform tasks of daily living.
- Trial name
- NCC-1701 (NCT03100110)
- Testing
- NeuroCognitive Communicator
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Ottawa Hospital Research Institute