Clinical trials: Motor Function
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Cognitive Performance, Academic Performance
Acute Effects of Active Breaks and Physically Active Learning in University Students
This multicenter randomized crossover study will examine the acute effects of four classroom break conditions on executive functions, immediate academic performance, perceived exertion, and interest-enjoyment in university…
- Trial name
- PAL UNI (NCT07809750)
- Testing
- Sedentary Academic Review, Active Break, Physically Active Learning
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Spinal Muscular Atrophy
Aerobic Training in Patients With Spinal Muscular Atrophy Type III
Spinal muscular atrophy type III, (SMAIII) is a disease in the nerve cells in the spinal cord which leads to to progressive muscle weakness and atrophy. No effective treatment is available for SMA.
- Trial name
- NCT02003937
- Testing
- Aerobic conditioning
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Cognitive Dysfunction
Endurance-strength Training in Obese Women
The aim of this study was to compare the effects of three months' endurance training and three months' endurance-strength training on selected psychological aspects in women with abdominal obesity.
- Conditions
- Obesity, Cognitive Dysfunction, Physical Exercise
- Trial name
- PSYCHENDOFIT (NCT04793451)
- Testing
- Endurance training, Endurance-strength training
- Where
- Poland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Physical Activity, Biological Aging
Exercise Referral Schemes Enhanced by Self-Management Strategies to Battle Sedentary Behaviour
The increase of the elderly population leads to increased prevalence of frailty, risk for poor health outcomes, and related health and social care costs.
- Conditions
- Physical Activity, Biological Aging, Frail Older Adults, Controlled Clinical Trials, Randomized
- Trial name
- SitLESS (NCT02629666)
- Testing
- ERS and/or Self-management Strategies
- Where
- Spain
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Forward Head Posture
Effects of Forward Head Posture on Cervical Proprioception, Muscle Endurance, and Cardiopulmonary Function During Cognitive-Motor Tasks Among University Students
Forward head posture is commonly observed among university students and may influence cervical sensorimotor function and physiological responses during functional activities.
- Trial name
- NCT07403422
- Testing
- No intervention
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Abeer Abdrabo
Child Development
Effects of Application of a Motor Programme on Neurological Maduration in Children
The persistence of primitive reflexes in school-age children can affect neuromotor maturation. Some studies link the persistence of primitive reflexes with specific learning difficulties, low academic performance…
- Trial name
- Move&Learn (NCT06030310)
- Testing
- The developmental Exercise Programme of INPP
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Physical Inactivity, Healthy Aging
Cost-effectiveness and Efficacy of Different Physical Exercise Interventions (ExerMOT4Health)
Online exercise has increased in popularity during the pandemic, but there is no evidence of its feasibility and benefits in older people and the influence of motivational strategies.
- Conditions
- Physical Inactivity, Healthy Aging, Older Adult
- Trial name
- ExerMOT4Health (NCT06425679)
- Testing
- Supervised synchronous online exercise intervention without motivational strategies, Supervised synchronous online exercise intervention with motivational strategies, Supervised face to face exercise intervention without motivational strategies
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Aggressive Behavior
Brain Changes in Adolescents While Imagining and Observing Aggressive Behavior
This study will use functional magnetic resonance imaging (fMRI) to examine what happens in the brains of adolescents when they are exposed to violent media and how imagining aggressive behavior affects brain function.
- Trial name
- NCT00267891
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Anterior Cruciate Ligament Injuries
Muscle Architecture and Anterior Cruciate Ligament
The aim of this study is to examine the effects of plyometric training on biceps femoris longus (BFl) and vastus lateralis (VL) muscle architecture in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04690127
- Testing
- Plyometric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stem Cell Transplantation
Physical Deteriorations in Allo-HSCT.
Limited number of studies reported impairments in physical activity, exercise capacity and quality of life of allogeneic hematopoietic stem cell transplantation (allogeneic-HSCT) recipients.
- Trial name
- NCT03606005
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Gazi University
HIV-Associated Cognitive Motor Complex
Mild Neurocognitive Disorder in HIV Infection of the Brain
Background: Some people with human immunodeficiency virus (HIV) develop problems with thinking and concentration when the virus affects the brain. This is known as mild neurocognitive disorder (MND).
- Trial name
- NCT01547754
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Peripheral Arterial Disease
Maximal Exercise Capacity, Physical Activity and Respiratory Muscle Strength in Peripheral Artery Disease
The primary aim of the study is to evaluate the maximal and submaximal exercise capacity in patients with peripheral artery disease (PAD).
- Trial name
- NCT03458754
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Overweight, Obese
Evaluating the Effects Two Diets Combined With Exercise in Persons With Abdominal Obesity (The SHAPE5 Study)
Abdominal obesity, which is affected by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obese, Sedentary, Abdominal Obesity
- Trial name
- SHAPE5 (NCT00990457)
- Testing
- Weight Loss Diets Plus Exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mountain Sickness Acute
Breathing Training to Improve Human Performance at High Altitude
Individuals traveling to altitudes above 8,000 feet may suffer from impaired exercise and cognitive performance, and acute mountain sickness (AMS).
- Trial name
- NCT03530163
- Testing
- Respiratory Muscle Training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Foot Diseases
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
- Trial name
- NCT07260747
- Testing
- VR Biodex Group, Video-Based VR Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
COPD, Tetrahydrobiopterin Deficiency
O2 Transport and Utilization in Health and Lung Disease
Skeletal muscle dysfunction is a frequent and clinically relevant systemic manifestation of Chronic Pulmonary Obstructive Disease (COPD), which is still poorly understood.
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Trial name
- NCT04014712
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Cardiometabolic Risk, Executive Function
Effects of Diet and Exercise Interventions on Cardiometabolic Risk Markers, Executive Function, and Intestinal Flora
The purpose of this study is to estimate the effects of diet and exercise interventions on body weight, cardiovascular metabolic markers, executive function, and intestinal flora among undergraduate students, as well as the…
- Conditions
- Cardiometabolic Risk, Executive Function, Intestinal Microbiome
- Trial name
- NCT04834687
- Testing
- Exercise, Diet
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University
Physical Activity
Small-sided Ball Game Training and Protein Intake in Older Adults
The effect of small-sided team sport training and protein intake on muscle mass, physical function, and adaptations important for health in untrained older adults was examined.
- Trial name
- NCT03120143
- Testing
- Small-sided ball game training with high protein intake, Small-sided ball game training with low protein intake
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen