Clinical trials: Motor Memory
Central Nervous System Diseases
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory
The investigators hypothesize that ten sessions of repetitive transcranial magnetic stimulation yield ability to upregulate the function of primary motor cortex and prefrontal cortex that play key roles in motor and frontal…
- Trial name
- NCT02006615
- Testing
- Functional near infrared spectroscopy, rTMS
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Parkinson's Disease
Cognitive-motor Training for PD
This study will evaluate gait when individuals with Parkinson's disease (PD) are walking and how walking changes when challenged to perform a functional cognitive task simultaneously.
- Trial name
- NCT01917903
- Testing
- Gait-cognitive training, Identification of at risk variables
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stony Brook University
Motor Memory
Enhancing Motor Task Training by Action Observation Watching Others Perform the Task
This study will determine how the brain learns a new motor task when the subject practices the task and watches others perform it (action observation) at the same time.
- Trial name
- NCT00393432
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Memory Deficits, Aging
The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.
The aim of this project is to estimate the effects of therapy with dance and movement and Tai Chi on irisin plasma levels, a myokine with proven neuroprotective effects, in the context of baseline levels of cognitive function and…
- Conditions
- Memory Deficits, Aging, Cognitive Impairment, Physical Activity
- Trial name
- NCT05363228
- Testing
- Therapy by Dance and Movement, Tai Chi
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Elderly
Physical Activity and Motor Memory in Pedal Dexterity
The main purpose of this study was to investigate if a six months period of physical exercise, could improve motor memory consolidation in elderly people on pedal dexterity
- Trial name
- NCT02731274
- Testing
- Regular physical activity in Motor memory consolidation
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Castelo Branco
Aging
Neuroimaging Study of Exercise and Memory Function
The investigators are examining the effects of exercise and cardiovascular fitness on cognitive processes, brain function, and the amount of several proteins in the blood.
- Trial name
- EMF (NCT02057354)
- Testing
- Aerobic Exercise, Non-Aerobic Exercise
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Boston University
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Autism Spectrum Disorder
A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)
This study will attempt to study the effect of memantine, on memory, and motor praxis/expressive language skills in children with autism.
- Trial name
- NCT01372449
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Evdokia Anagnostou
Healthy Preschoolers
Fundamental Movement Skills Training Improves Executive Functions in Preschoolers
This randomized controlled trial investigated the effects of a 12-week structured fundamental movement skills (FMS) training program on executive functions in 34 healthy preschoolers aged 5-6 years.
- Trial name
- FMS-EF-RCT (NCT07725354)
- Testing
- Fundamental Movement Skills Training, Regular Physical Activity
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Xi'an Physical Education University
Aging, Physical Activity
Exercise Periodization and Older Adults
The present study aimed at investigating the effects of two different resistance training protocols - nonperiodized (NP) and daily undulating periodization (DUP) - on hemodynamic, morphofunctional and cognitive parameters of…
- Conditions
- Aging, Physical Activity, Sarcopenia, Cognitive Decline
- Trial name
- NCT03443375
- Testing
- Physical exercise
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
PARKINSON DISEASE (Disorder)
Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation
The purpose of this research study is to examine the effects of transcranial Direct Current Stimulation (tDCS) on verbal retrieval and cognition and sensorimotor control and to determine if tDCS can be used as a way to improve…
- Trial name
- NCT07534397
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Mild Cognitive Impairment
Retaining Cognition While Avoiding Late-Life Depression
This study will adapt Problem Solving Therapy (PST) for individuals with mild cognitive impairment (MCI) as an intervention for preventing major depression (DEP).
- Trial name
- RECALL (NCT01886586)
- Testing
- Problem Solving Therapy, Problem Solving Therapy + Exercise, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- University of Pittsburgh
Executive Functions, Memory Functions
Multi-domain Versus Uni-Domain Training on Executive Control and Memory Functions of Older Adults
Age-related cognitive decline affects negatively daily living and quality of life of older adults. Previous research has shown a moderate impact of cognitive and physical training on the cognitive functioning of elders.
- Trial name
- VIBAL (NCT03823183)
- Testing
- Cognitive training, Physical training, Cognitive control
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Aerobic Exercise, Anaerobic Exercise
The Effect of Physical Activity on the Brain
Physical activity is thought to increase overall body functions and to decrease cardiovascular and stroke risk factors. Now the question arose, wether enhanced exercise could also exert positive influence on cognition in the…
- Conditions
- Aerobic Exercise, Anaerobic Exercise, Unchanged Condition
- Trial name
- NCT01475396
- Testing
- exercise
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Cognitive Impairment
The Mental Activity and eXercise Trial for Seniors
The primary objective of this study is to conduct a randomized, controlled trial to determine whether engaging in mental activity or exercise, either alone or in combination, improves cognitive function in non-demented, inactive…
- Trial name
- MAX (NCT00522899)
- Testing
- Group 1, Group 2, Group 3
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of California, San Francisco
Alzheimer s Disease, Healhty
Validation of a Remediation Method for Memory Impairments Through Motor Encoding in Patients With Alzheimer's Disease
In France, over 1.5 million people suffer from mild cognitive impairment, often a precursor to Alzheimer's disease (AD), whose global prevalence could reach 153 million by 2050.
- Trial name
- ADACT (NCT07632755)
- Testing
- Control condition, Motor mental imagery, Action execution
- Where
- 3 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Multiple Sclerosis
Memory Rehabilitation Strategies in Patients With Multiple Sclerosis
The clinical characteristics of MS are extremely variable from one patient to another. In about 60% of cases, motor disabilities are associated with cognitive deficits.
- Trial name
- NCT05462678
- Testing
- Cognitive Rehabilitation, Combined Rehabilitation, Motor Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Multiple Sclerosis
Patient Centered Outcomes Analysis for MS Using a Mobile Application
Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that can impact all aspects of nervous system function.
- Trial name
- NCT04281160
- Testing
- BeCare Mobile App
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BeCare Link LLC
Trauma, Psychological, Post Traumatic Stress Disorder
Motor Interference Therapy For Traumatic Memories
The aim of the study is to compare the effect of motor interference therapy (TIM) to reduce the intensity of discomfort (distress) generated by a traumatic memory compared to a relaxation control maneuver, immediately after the…
- Trial name
- TIMCO (NCT03627078)
- Testing
- motor interference therapy, Relaxation exercises
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez