Clinical trials: Motor Recovery
Stroke Sequelae
Virtual Reality Versus Constraint-induced Movement on Hemiparesis in Cerebrovascular Event
The objective of this clinical trial is to measure the effect of Rehabilitation with Virtual Reality or Modified Constraint-Induced Movement Therapy on hemiparesis in patients with Cerebral Vascular Event.
- Trial name
- NCT05875116
- Testing
- Virtual reality, Modified constraint-induced movement therapy, Usual Physical and Occupational Therapy
- Where
- Mexico
- Volunteers
- 119 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Stroke, Stroke, Ischemic
MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits
This is a multi-center, randomized, double-blind, placebo-controlled trial of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 high-dose twice a day, MLC1501…
- Conditions
- Stroke, Stroke, Ischemic, Strokes Thrombotic, Stroke Sequelae
- Trial name
- MAESTOSO (NCT05289947)
- Testing
- MLC1501
- Where
- 11 sites in Philippines, Singapore
- Volunteers
- 303 people
- Sponsor
- Moleac Pte Ltd.
Cerebrovascular Accident, Healthy
Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Disability
This study will use transcranial magnetic stimulation (TMS) to identify interactions between the unaffected and affected side of the brain in stroke patients.
- Trial name
- NCT00029718
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Exercise, Metabolism
Ketone Esters and Metabolism During Recovery from Endurance Exercise
Infusion of beta-hydroxybutyrate can suppress endogenous glucose production, which may result in increased net liver glycogen storage.
- Trial name
- NCT06846840
- Testing
- Ketone ester
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Bath
Inflammatory Response, Metabolic Disturbance
Beet Supplementation, Exercise, Inflammation
This study will determine if ingesting a beet-based supplement with nitrates for 2 weeks moderates exercise-induced inflammation.
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05907135
- Testing
- Beet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Stroke, Subacute
Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients
Stroke is the third common cause of adult disability in dveloped countries. Early identification of the potential for motor recovery is important to avoid 'learned disuse' and to initiate appropriate therapy with achievable…
- Trial name
- NCT03243318
- Testing
- MEPs induced by TMS
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Hospital Authority, Hong Kong
Stroke
Neurofeedback for Upper-limb Recovery After Stroke
Interventional study with minimal risks and constraints, prospective, monocentric.
- Trial name
- NeuroFB-AVC (NCT03766113)
- Testing
- Neurofeedback coupling electroencephalogram and functional MRI in time actual, Electroencephalogram-neurofeedback program or Neurofeedback-free mental imaging program with electroencephalogram recording, Neurofeedback coupling electroencephalogram and functional MRI in time actual or a neurofeedback-free mental imaging program with electroencephalogram recording
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Peripheral Nerve Injuries
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting.
- Trial name
- RANGER® (NCT01526681)
- Testing
- Processed Human Nerve Graft, Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc., Autogenous Nerve Graft
- Where
- 49 sites in United States, Austria and 2 more
- Volunteers
- 3,126 people
- Sponsor
- Axogen Corporation
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Stroke
Impact of a Focal Muscle Vibration Protocol in Front of the the Anterior Tibial Muscle in the Subacute Post-stroke Period on Motor Recovery in Hemiplegic Patients.
In about 40 percent of cases, after a stroke, neuromotor impairment leads to activity limitations and the development of chronic functional disorders, which have a significant impact on patient autonomy.
- Trial name
- VIBRATAC (NCT04737018)
- Testing
- Fugl-Meyer Assessment (FMA), Medical Research Concil (MRC), 2 Minute Walk Test (2MWT)
- Where
- 2 sites in France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke, Ischemic, Stroke
Comparison of the Effectiveness of Mirror Therapy and Mirror Mode of Hand Robot in Stroke
The goal of this clinical trial is to compare the effectiveness of conventional mirror therapy and robotic mirror mode training in promoting upper extremity motor recovery in adult patients with ischemic stroke during the early…
- Conditions
- Stroke, Ischemic, Stroke, CVA (Cerebrovascular Accident)
- Trial name
- mirror_robot (NCT07435688)
- Testing
- Hand Robot Mirror Mode, Therapy Mirror
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Zeynep Lide Uz
Stroke
ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke
Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis for recovery has improved…
- Trial name
- NCT06496529
- Testing
- DoF intervention, Task intervention
- Where
- 4 sites in Chile
- Volunteers
- 44 people
- Sponsor
- University of Chile
Musculoskeletal Pain, Healthy
Multivariable Recovery After Exercise-induced Muscle Pain in the Forearm Muscles
This study investigates the evolution of sensory, motor and tissue variables following exercise-induced pain in wrist extensor muscles in healthy subjects.
- Conditions
- Musculoskeletal Pain, Healthy, Delayed Onset Muscle Soreness
- Trial name
- NCT04012203
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Depression
Stress Reactivity of Physical Stressor on Depression
Depressive elderly individuals have showed higher basal level of cortisol and lower level of dehydroepiandrosterone (DHEA). Moreover, changes on these hormone levels have also observed in reactivity of an acute stress, such as…
- Trial name
- NCT01791023
- Testing
- Physical exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Cerebral Palsy (CP)
Structured Graphic Motor Therapy in Pediatric CP
Structured Graphic Motor Therapy (SGMT) is a novel task-oriented rehabilitation approach that uses standardized, progressively challenging drawing trajectories to improve upper-limb motor function in children with cerebral palsy.
- Trial name
- SGMT-CP (NCT07753083)
- Testing
- Structured Graphic Motor Therapy (SGMT), Conventional Upper-Limb Rehabilitation
- Where
- Armenia
- Volunteers
- 12 people
- Sponsor
- Armenian State Institute of Physical Culture and Sport
Stroke, Stroke Rehabilitation
Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE)
This study is a multicentric randomized controlled trial evaluating the effectiveness of digital technology, specifically a smartphone with integrated VR-and AR-based intervention, for at-home rehabilitation after stroke.
- Conditions
- Stroke, Stroke Rehabilitation, Chronic Stroke Patients, Post Stroke Recovery
- Trial name
- PHRASE-2024 (NCT06885502)
- Testing
- RGS
- Where
- 2 sites in Romania, Spain
- Volunteers
- 70 people
- Sponsor
- Eodyne Systems SL
Stroke, Cerebrovascular Disorders
The Technology-assisted, High Intensive, Task-oriented Exercise Trial
The interventional study aims to increase the knowledge on arm and hand rehabilitation after stroke within community-based services.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TECHITO (NCT03396939)
- Testing
- Orthosis
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Rheumatoid Arthritis, Cryotherapy Effect
Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial Stiffness
The purpose of this study is to analyze the long-term effects of a physical exercise program on the cardiovascular system of people with Rheumatoid Arthritis (RA).
- Conditions
- Rheumatoid Arthritis, Cryotherapy Effect, Physical Activity
- Trial name
- PREXCRIM (NCT03911830)
- Testing
- Exercise followed cold water immersion
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stroke
Clinical Study to Investigate the Safety and Efficacy of MLC601 in 150 Iranian Patients After Stroke
To investigate the safety and efficacy of MLC601 (NeuroAideTM) as a Traditional Chinese Medicine on motor recovery after ischemic stroke.
- Trial name
- NCT01336153
- Testing
- MLC601
- Volunteers
- 150 people
- Sponsor
- Shahid Beheshti University
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego