Clinical trials: Motor Recovery
Stroke, Upper Extremity Paresis
NIBS With mCIMT for Motor and Functional Upper Limb Recovery in Stroke Patients.
Stroke is one of the leading causes of serious long-term impairment. According to the estimates, 12,500 people suffer a new or recurrent ischemic stroke in Chile annually, which shows the magnitude of the problem.
- Conditions
- Stroke, Upper Extremity Paresis, Electric Stimulation, Occupational Therapy
- Trial name
- NCT03452254
- Testing
- Active Bihemispheric Transcranial direct current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 2 sites in Chile
- Volunteers
- 70 people
- Sponsor
- University of Chile
Lung Neoplasms, Rehabilitation
Rehabilitation for Thoracoscopic Lobectomy
The main aim of this research is to compare the functional recovery after discharge with the preoperative physical activity as a hypothesis generating study.
- Conditions
- Lung Neoplasms, Rehabilitation, Exercise, Pain, Postoperative
- Trial name
- NCT04502654
- Testing
- Actiwatch 2 (Philips Respironics, Murrysville, USA)
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Adult, Fatigue
Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals
The purpose of this protocol is to investigate the role of expired non-metabolic carbon dioxide in the relationship between fatigability and recovery and the response to aerobic exercise training in healthy individuals.
- Trial name
- NCT03800342
- Testing
- Aerobic Exercise Training
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- George Mason University
Stroke
Evaluation of Whether Functional Strength Training Can Enhance Motor Recovery of the Upper Limb After Stroke
The purpose of this study is to test the hypothesis that adding functional strength training to UK conventional therapy improves muscle function and walking than either UK conventional therapy alone or increased intensity of UK…
- Trial name
- NCT00360789
- Testing
- Conventional UK physical therapy, Increased intensity of UK conventional physical therapy (PT), UK conventional PT plus functional strength training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- St George's, University of London
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Agitated; State, Acute Reaction to Stress
Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?
In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas…
- Trial name
- NCT03862391
- Testing
- Analgesics, Antiemetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Stroke
Effect of Upper Extremity Rehabilitation Using Immersive Virtual Reality in Chronic Stroke Patients.
The study aimed to investigate the effect of exergames using virtual reality with head mounted device on motor recovery of upper extremities in chronic stroke patients.
- Trial name
- NCT05148052
- Testing
- Virtual reality exergames, Conventional occupational therapy
- Where
- 3 sites in South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Hospital
Stroke, Upper Extremity Paresis
Telerehabilitation for Hand Function in Stroke Patients
Stroke is a leading cause of adult disability worldwide, with upper limb impairment significantly reducing independence. Traditional outpatient rehabilitation poses challenges for patients with mobility limitations, financial…
- Conditions
- Stroke, Upper Extremity Paresis, Hand Functions
- Trial name
- TeleStroke-PK (NCT07666906)
- Testing
- Telerehabilitation with Conventional Therapy, Conventional Outpatient Rehabilitation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Spinal Cord Injury
AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)
Spinal cord injury (SCI) often results in persistent motor deficits that are inadequately addressed by conventional rehabilitation.
- Trial name
- AIM RECOVER (NCT07452133)
- Testing
- Dynamic stimulation, Static stimulation
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Stroke, Cerebrovascular Disorders
Cost-effectiveness of Forced Aerobic Exercise for Stroke Rehabilitation
The purpose of this study is to investigate whether aerobic exercise improves the participant's ability to recover function in the arm and leg affected by the participant's stroke.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- NCT03819764
- Testing
- Aerobic Exercise, Upper Extremity Repetitive Task Practice
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Stroke, Hemiplegia and Hemiparesis
The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world.
- Trial name
- EFODIN (NCT07056049)
- Testing
- High dosage, high intensity motor rehabilitation
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Adi Negev-Nahalat Eran
Major Depressive Disorder, Depression Moderate
Exercise Recovery From Persistent Depression: A Thematic Analysis
Depression is a leading cause of disability worldwide and poses a large economic burden in the UK. There is evidence that exercise is beneficial in the management of depression and NICE now recommends group exercise programs as a…
- Conditions
- Major Depressive Disorder, Depression Moderate, Depression Severe
- Trial name
- NCT05539495
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Nottingham
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Muscle Damage, Muscle
The Effect of Vicia Faba Hydrolysate Supplementation on Muscle Strength Recovery
To investigate the effect of Vicia faba protein concentrate, a protein derived from Fava bean extract, on delayed onset muscle soreness (DOMS).
- Trial name
- NCT06837298
- Testing
- PeptiStrong® supplement capsules following muscle damaging exercise on Day 14
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Stroke
Resistance Training and Constrained Induced Movement Therapy on Upper Extremity Motor Recovery and Quality of Life in Sub-acute Stroke Patients
This study explored two common rehabilitation strategies-Constraint-Induced Movement Therapy (CIMT) and Resistance Training (RT)-to help stroke survivors improve movement and function in their weaker arm.
- Trial name
- NCT06933147
- Testing
- Constraint-Induced Movement Therapy (CIMT), Resistance Training (RT)
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Stroke
Neuroregeneration Enhanced by Transcranial Direct Current Stimulation (TDCS) in Stroke
Testing the hypothesis that non-invasive brain stimulation by transcranial direct current stimulation (tDCS) combined with functional training in the subacute phase of first-ever stroke will enhance functional regeneration…
- Trial name
- NETS (NCT00909714)
- Testing
- DC-Stimulator to apply tDCS
- Where
- 11 sites in Austria, Germany and 1 more
- Volunteers
- 119 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Mental Health Wellness
Recovery Strategies Based on Mindfulness and Physical Exercise on Levels of Stress and Inmunoglobulin A
The present study aims to compare the differential effects of mindfulness meditation (MBI) and physical exercise (PE) on different stress, academic performance and health variables (self-report means and biological measure of IgA…
- Trial name
- ERME-IgA (NCT05771649)
- Testing
- Mindfulness-based intervention, Physical exercise
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Upper Limb Ischemia, Stroke
Identification of Non-motor Brain Areas Involved in Upper Limb Motor Recovery After Stroke
Why: Upper-limb recovery post-stroke is challenging. Rehabilitation, aiming to induce plasticity takes an important place in patients' treatment.
- Trial name
- NOMO-Stroke (NCT05313776)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier