Clinical trials: Motor Recovery
Ischemic Stroke
MSC Secretome and rTMS for Motor Recovery After Subacute Ischemic Stroke
This randomized, double-blind, controlled clinical trial evaluates the effectiveness and safety of combined mesenchymal stem cell (MSC) secretome and repetitive transcranial magnetic stimulation (rTMS) for motor recovery in…
- Trial name
- NCT07874269
- Testing
- Mesenchymal Stem Cell-Derived Secretome, Active Repetitive Transcranial Magnetic Stimulation
- Where
- Indonesia
- Volunteers
- 205 people
- Sponsor
- Jumraini Tammasse
Stroke
Changes in Brain Activity Associated With Upper Limb Motor Recovery
This study is to investigate changes in brain activities in acute stroke patients , and to correlate findings with clinical outcome measures.
- Trial name
- NCT02325427
- Testing
- tDCS
- Where
- Singapore
- Volunteers
- 8 people
- Sponsor
- National University Hospital, Singapore
First Ever Clinical Stroke, Ischemic Stroke
Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic Stroke
Rehabilitation after stroke improves motor functions by promoting plastic changes however, after completing standard rehabilitation, 50-60% of patients still exhibit some degree of motor impairment and require at least partial…
- Conditions
- First Ever Clinical Stroke, Ischemic Stroke, Subacute Phase, Persistent Hemiparesis of Upper Extremity
- Trial name
- RECOMBINE (NCT01644929)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- 3 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Dr. med. Carlo Cereda
Stroke Rehabilitation
Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients.
The aim of the vibration intervention proposed in the current study is to allow a better neuromotor recovery in subacute stroke patients when compared with standard rehabilitation alone.
- Trial name
- NEUROVIB-AVC (NCT05945212)
- Testing
- Vibration, 10 meters Walk Test, 2 Minute Walk Test (2MWT)
- Where
- 7 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acute Stroke
Interdisciplinary Home Rehabilitation of Patients With Stroke. A Randomised Controlled Intervention Trial.
Objective: To evaluate the effect of interdisciplinary home rehabilitation of patients with acute stroke. The trial seeks to evaluate: 1.
- Trial name
- NCT00626353
- Testing
- Home-based rehabilitation, Standard care
- Where
- Denmark
- Volunteers
- 71 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Long QT Syndrome, Cardiac Repolarization
Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Background. In congenital long QT syndrome type 1 (LQT1), episodes of ventricular tachycardia are usually triggered by exercise and can be prevented in most patients by beta-blocker therapy.
- Trial name
- NCT00588965
- Testing
- Propranolol LA
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Muscle Injury
Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise
A randomised placebo controlled, double-blind, 30 Volunteer trial of Elio™ administered 2.4 grams per day in assessing its effects on post-exercise strength recovery and increases in markers associated with muscle injury and…
- Trial name
- NCT05159375
- Testing
- Elio, SMCC
- Where
- Ireland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Cerebral Palsy, Hemiplegia
The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP
The purpose of this study is to assess the use of a commercially available arm weight supporting training system (Armeo®Spring) in conjunction with Constraint Induced Therapy (CIT) for improving upper extremity function for…
- Conditions
- Cerebral Palsy, Hemiplegia, Upper Extremity Weakness
- Trial name
- NCT02914925
- Testing
- ArmeoSpring/CIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St Mary's Hospital for Children
Stroke Rehabilitation
Vibratory Perturbation-based Pinch Task Training for Stroke Patients
The investigator assumed that perturbed-event-induced vibrotactile cueing enable more precision arm movement adjustment, sensory function and dexterity improvement in the spastic arm.
- Trial name
- NCT03798340
- Testing
- Vibratory perturbed task-specific movement training, Traditional task-oriented facilitation, Sensorimotor training
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Rheumatoid Arthritis, Cryotherapy Effect
Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial Stiffness
The purpose of this study is to analyze the long-term effects of a physical exercise program on the cardiovascular system of people with Rheumatoid Arthritis (RA).
- Conditions
- Rheumatoid Arthritis, Cryotherapy Effect, Physical Activity
- Trial name
- PREXCRIM (NCT03911830)
- Testing
- Exercise followed cold water immersion
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hemiparesis, Stroke Sequelae
Neural Mechanisms of Motor Recovery With Technology Assisted Training
Stroke is a leading cause of disability that often impairs arm function and activities of daily living. The costs of rehabilitation are significant and practical constraints often limit therapy to the first few months after…
- Trial name
- NCT05560867
- Testing
- robot-assisted training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects.
- Trial name
- NCT03486795
- Testing
- M1 stimulation, PMC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke, Stroke Rehabilitation
Evaluating Functional Outcomes of 3D-Printed Splints in Post-Stroke Upper Limb Recovery
This study aims to evaluate the upper limb motor recovery using a 3D-printed dynamic orthosis compared to a conventional one as part of a rehabilitation program in individuals with chronic stroke.
- Conditions
- Stroke, Stroke Rehabilitation, Hemiparesis of the Upper Limb Following Stroke
- Trial name
- 3D-splint (NCT07243314)
- Testing
- 3D Printed splint, conventional splint
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Saud University
Stroke
FES VS Constrained Induced MT Recovery and Spasticity in Upper Limb Hemiparetic Ischemic Patients
To determines the effects of Functional Electrical Stimulation versus Constrained Induced Movement Therapy for motor recovery and spasticity in Upper Limb Hemiparetic Chronic Ischemic Stroke Patients
- Trial name
- NCT05854121
- Testing
- Functional Electrical Stimulation, Constrained Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Superior University
Cervical Spinal Cord Injury
Linking Brain to Behaviour Research in SCI
Introduction In recent years, client-centred and task-oriented training have emerged as important methods in rehabilitation including the rehabilitation of persons with spinal cord injury (SCI).
- Trial name
- NCT01963026
- Testing
- ToCUEST featuring a 'variable practice' approach., ToCUEST featuring a 'constant practice' approach.
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Adelante, Centre of Expertise in Rehabilitation and Audiology
Stroke
Art Therapy and Its Effect on Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery
The target disease of this study is subacute ischemic stroke, a condition characterized by reduced blood flow to brain tissue due to arterial blockage, with a specific focus on the subacute recovery phase.
- Trial name
- NCT06709950
- Testing
- Art therapy, Regular therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chonbuk National University
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Ischemic Stroke, Hemiplegia
Repetitive Transcranial Magnetic Stimulation for Motor Recovery After Ischemic Stroke (rTMS-MOTOR)
Ischemic stroke is a leading cause of long-term motor disability, frequently resulting in hemiplegia and limitations in daily activities and quality of life.
- Conditions
- Ischemic Stroke, Hemiplegia, Motor Function Impairment
- Trial name
- rTMS-MOTOR (NCT07369648)
- Testing
- Active repetitive transcranial magnetic stimulation, Conventional motor rehabilitation
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Hanoi Medical University
Stroke, Stroke, Ischemic
Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke (TRAIL-RCT)
The purpose of this study is to compare the effectiveness of a 4-week lower extremity telerehabilitation protocol with aims to improve lower extremity function to a 4-week attention-controlled education program on lower extremity…
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Cerebral Injury
- Trial name
- TRAIL-RCT (NCT04908241)
- Testing
- TRAIL, EDUCATION
- Where
- 5 sites in Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Stroke
Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke
Paralysis following stroke stems not only from the loss of neurons killed by the stroke but also from the loss of neurons lying dormant in the stroke hemisphere.
- Trial name
- rTMS (NCT00913211)
- Testing
- rTMS, Motor learning training, rTMS and Tracking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota