Clinical trials: Motor Recovery
Stroke, Upper Extremity Paresis
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a person recover hand movement.
- Conditions
- Stroke, Upper Extremity Paresis, Hemiplegia
- Trial name
- NCT05866003
- Testing
- Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, CCFES with Occupational Therapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- MetroHealth Medical Center
Lower Extremity Explosive Power Deficit, Sports Recovery
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period.
- Conditions
- Lower Extremity Explosive Power Deficit, Sports Recovery, Basketball Performance, Muscle Fatigue
- Trial name
- NCT07604948
- Testing
- Ischemic Preconditioning
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University
Chronic Spinal Cord Disorder
The Effects of rTMS and tDCS Combined With Robotic Rehabilitation In Patients With Spinal Cord Injury
The purpose of this study is to assess the effect of rTMS and tDCS combined with robotic therapy on motor functional recovery and gait parameters
- Trial name
- NCT06188130
- Testing
- active rTMS, active tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Motor Recovery
BreEStim for Post-Stroke Motor Recovery
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750551
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Sport Recovery, Aminoacidemia
The Effects of Cold-water Immersion on Exercise Performance Recovery and Postprandial Plasma Aminoacidemia
In order to optimize sports performance, high-level athletes are required to manage conflicting training objectives, which often result in periods of high-volume training.
- Conditions
- Sport Recovery, Aminoacidemia, Cold-water Immersion
- Trial name
- NCT06698237
- Testing
- immediate cold-water immersion, delayed cold-water immersion, immediate thermoneutral water immersion
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- McGill University
Stroke
Study to Enhance Motor Acute Recovery With Intensive Training After Stroke
Stroke often results in limitation of arm movements, from which many people do not fully recover. We believe that early and intensive therapy is important to enhance recovery of arm movements after stroke.
- Trial name
- SMARTS2 (NCT02292251)
- Testing
- Device-assisted therapy, Therapy-based occupational therapy
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University
Stroke, Hemiplegia
CUped: An Approach to Motor Recovery Post-Stroke, Not Compensation
The goal of lower limb rehabilitation after stroke is recovery of independent walking at home and in the community. Few stroke survivors achieve this goal.
- Trial name
- NCT06329765
- Testing
- Exercise with CUped - a motor-assisted, split crank pedaling device and undergo 50 m of gait training.
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Marquette University
Stroke, Upper Extremity Paresis
Telerehabilitation for Hand Function in Stroke Patients
Stroke is a leading cause of adult disability worldwide, with upper limb impairment significantly reducing independence. Traditional outpatient rehabilitation poses challenges for patients with mobility limitations, financial…
- Conditions
- Stroke, Upper Extremity Paresis, Hand Functions
- Trial name
- TeleStroke-PK (NCT07666906)
- Testing
- Telerehabilitation with Conventional Therapy, Conventional Outpatient Rehabilitation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Healthy
The Investigators Conducted a Study to Examine the Impact of Wild Ginseng Extract (WG) on Exercise Performance, Cognitive Function, and Fatigue Recovery Among Twelve Healthy Adult Males
The goal of this clinical trial was to learn if Wild Ginseng extract (WG) influences exercise performance, cognitive function, and fatigue recovery from the exercise.
- Trial name
- NCT06679725
- Testing
- Wild ginseng extract
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Texas A&M University San Antonio
Fracture Femur, Hip Arthroplasty Replacement
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
The aim of this study is to evaluate whether integrating a technology-based rehabilitation approach with conventional therapies in the rehabilitation of patients with proximal femoral fracture may be advantageous compared with…
- Conditions
- Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
- Trial name
- FEWF (NCT07392515)
- Testing
- Experimental intervention - integrated treatment with a sensor-based device, Conventional rehabilitation intervention
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- C.O.T. Cure Ortopediche Traumatologiche S.p.A.
Acute Stroke
Repeated Muscle Vibration in Acute Stroke
prospective randomized double-blind sham-controlled study aimed to investigate the effects of Repeated Muscle Vibration (rMV) on motor recovery in acute stroke patients, treated within 72 hours from symptoms onset
- Trial name
- NCT03697525
- Testing
- Vibration
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Roma La Sapienza
Healthy
Effects of Water-soluble Olive Extract Supplementation
Six weeks of supplementation of an olive extract will: Improve antioxidant status Reduce inflammation Reduce muscle damage Improve exercise performance Improve exercise recovery as compared to a placebo.
- Trial name
- NCT01113827
- Testing
- Olive Extract
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Patients With Chronic Stroke
Enhanced Motor Recovery Using Serotonergic Agents in Stroke
The information derived from this study will be critical to establishing appropriate rehabilitative interventions post-stroke. In particular, traditional use of pharmacological agents to alter motor function post-stroke is…
- Trial name
- NCT01751854
- Testing
- SSRI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Effect of tDCS on Brain Organization and Motor Recovery
Neurological deficits and motor disorders are extremely common after stroke. Physical therapies can improve the autonomy of these patients, but despite an intensive stationary neurorehabilitation, severe deficits often persist.
- Trial name
- ESTCORM (NCT03342534)
- Testing
- DC-stimulator (Neuroconn, Germany)
- Where
- 2 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Adrian Guggisberg
Stroke Sequelae, Deep Brain Stimulation
Safety and Efficacy Study of Implantable Neuromodulation for Poststroke Hemiplegia
Background: Hemiplegia is a common complication after a stroke. Studies have shown that traditional medical and rehabilitation treatments are not good for improving patients' motor function, deep brain stimulation (DBS) and vagus…
- Conditions
- Stroke Sequelae, Deep Brain Stimulation, Vagus Nerve Stimulation, Motor Recovery
- Trial name
- NCT06121947
- Testing
- The DBS electrodes are implanted into MLR., The electrodes are implanted into the patient's vagus nerve
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese PLA General Hospital
Stroke, Post-Stroke Spasticity
ESTIM-UL: FES for Upper Limb Recovery After Stroke
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery…
- Conditions
- Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
- Trial name
- ESTIM-UL (NCT07513714)
- Testing
- Functional Electrical Stimulation (FES), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Spinal Cord Injuries
Neural Plasticity and Motor Recovery After Upper Extremity Motor Training in People With c-SCI
After spinal cord injury (SCI), there is a disruption in neural circuits resulting in paralysis. There is not yet a cure for paralysis.
- Trial name
- REPAIR-SCI (NCT06065384)
- Testing
- experimental group: intensive motor training, usual care
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 44 people
- Sponsor
- Annemie Spooren
Lung Neoplasms, Rehabilitation
Rehabilitation for Thoracoscopic Lobectomy
The main aim of this research is to compare the functional recovery after discharge with the preoperative physical activity as a hypothesis generating study.
- Conditions
- Lung Neoplasms, Rehabilitation, Exercise, Pain, Postoperative
- Trial name
- NCT04502654
- Testing
- Actiwatch 2 (Philips Respironics, Murrysville, USA)
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ACV
Motor Rehabilitation and Physical, Mental and Cognitive Health in Patients With Stroke
This study analyzes the effectiveness of a motor rehabilitation program in the functional recovery of stroke patients and its impact physiotherapy, occupational therapy, and neuropsychology are used to measure improvements in…
- Trial name
- NCT06840366
- Testing
- Lokomat intervention
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- University of Jaén
Forearm Surgeries, Brachial Plexus Blockade
Perfusion Index in Monitoring Recovery From Brachial Plexus Block After Forearm Surgery
Postoperative differentiation between residual regional anesthetic effect and other causes of persistent sensory or motor deficit is a common clinical problem after peripheral nerve blocks.
- Trial name
- NCT07909941
- Testing
- Perfusion index measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital