Clinical trials: Motor Recovery
Lower Limb Amputation Knee, Injuries
Virtual Reality Rehabilitation to Promote Motor Recovery in Amputees
Interventional, non-pharmacological crossover study aimed at identify statistically significant differences in postural stability and spatio-temporal gait cycle parameters in patients with lower limb amputation by means of…
- Conditions
- Lower Limb Amputation Knee, Injuries, Biomechanical Lesion
- Trial name
- NCT06295380
- Testing
- Virtual environment practiced on the Caren, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke, Acute
Establishing a Prognostic Model for Stroke Recovery
This main aim of the study is to investigate the changes in neurophysiological features after stroke, and its association with upper limb motor recovery, so as to establish a prognostic model for upper limb motor recovery after…
- Trial name
- NCT05332652
- Testing
- trancranial magnetic stimulation
- Where
- 2 sites in Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Stroke, Chronic Stroke Patients
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- NCT07631078
- Testing
- kTMP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Magnetic Tides
Stroke
Stroke Motor Recovery for the Hand and Fingers
The goal of this clinical trial is to compare two rehabilitation methods to improve finger movements in people who have had a stroke.
- Trial name
- NCT06604143
- Testing
- Quality Training, Goal Training
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Toronto
Agitation
Effect of Deksmedetomidine and Remifentanil in Extubation Agitation
To compare the effect of two different agents deksmedetomidine, remifentanil and placebo, agitation and recovery condition, on nasal septum operation.
- Trial name
- EA (NCT02104297)
- Testing
- deksmedetomidine, Remifentanil, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Spinal Cord Injury
Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia
In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after…
- Trial name
- NCT05157282
- Testing
- TESS, Training, Motor Task
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Exercise, Central Nervous System Tumors
POWER UP: Participating Online While Exercising to Recover Using Play
We will conduct a two-phase study. The first phase is to adapt and develop an active video game (AVG)-centered lifestyle physical activity (PA) intervention (POWER UP) for adolescents and young adults (AYA) with central nervous…
- Conditions
- Exercise, Central Nervous System Tumors, Tumors
- Trial name
- NCT05308407
- Testing
- Focus Groups, Pilot randomized controlled trial
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- M.D. Anderson Cancer Center
Stroke
FES VS Constrained Induced MT Recovery and Spasticity in Upper Limb Hemiparetic Ischemic Patients
To determines the effects of Functional Electrical Stimulation versus Constrained Induced Movement Therapy for motor recovery and spasticity in Upper Limb Hemiparetic Chronic Ischemic Stroke Patients
- Trial name
- NCT05854121
- Testing
- Functional Electrical Stimulation, Constrained Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Superior University
Stroke
Pilot Study - Comparison of Upper Body Ergometer Vs. Robot in Upper Extremity Motor Recovery Post-Stroke
We will test whether robot driven, goal directed, trajectory corrected exercise enhances motor outcome in the upper limb of stroke patients better than matched motor activity on an upper body ergometer (monark).
- Trial name
- NCT00343304
- Testing
- Robot, Ergometer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Burke Rehabilitation Hospital
Cancer, Dyspnea
Effects of a Specific Programme for the Recovery of Autonomy Plus Multimodal Physical Exercise in Oncology Patients With Dyspnoea
In recent years the survival of cancer patients has increased exponentially. But together with that survival, and due to the different oncological treatments, side effects have also increased significantly.
- Trial name
- NCT04766593
- Testing
- Oncological functional reeducation program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Motor Recovery
BreEStim for Motor Recovery in Chronic Stroke With Moderate Impairment After a Long-term Use (Pilot).
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04752319
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Thoracic Surgery
Surgical Prehabilitation on Autonomic Nervous System (TUNE)
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV).
- Trial name
- TUNE (NCT06398301)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Acute Stroke, Stroke, Ischemic
Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania
This is a phase II, randomized study of 120 adults age 18 or above who will prescribed 20mg daily Fluoxetine for 90 days following acute, ischemic stroke.
- Trial name
- MAMBO (NCT03728153)
- Testing
- Fluoxetine 20 MG Oral Tablet
- Where
- Tanzania
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Stroke
Art Therapy and Its Effect on Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery
The target disease of this study is subacute ischemic stroke, a condition characterized by reduced blood flow to brain tissue due to arterial blockage, with a specific focus on the subacute recovery phase.
- Trial name
- NCT06709950
- Testing
- Art therapy, Regular therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chonbuk National University
Chronic Stroke, Balance
"Effects of a Combined Repetitive Transcranial Magnetic Stimulation and Physical Therapy Protocol on Motor Function, Balance, and Quality of Life in Chronic Post-Stroke Hemiplegia: A Case Series"
Chronic post-stroke hemiplegia frequently results in persistent motor deficits, impaired balance, and reduced quality of life. Conventional physical therapy is fundamental for functional recovery; however, motor improvement often…
- Trial name
- NCT07597746
- Testing
- rTMS, physical therapy
- Volunteers
- 20 people
- Sponsor
- Sierra Varona SL
Spinal Anesthesia, Dexamethasone
Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
The goal of this clinical trial is to determine the effects of intravenous (IV) dexamethasone on spinal anesthesia in healthy women having an elective Cesarean delivery (CD) at the IWK Health Centre.
- Trial name
- NCT05731960
- Testing
- Dexamethasone, Metoclopramide
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- IWK Health Centre
Stroke, Motor
SSRIs and TDCS Enhance Post-stroke Motor Recovery
Post-stroke motor recovery is compelling but limited. Current rehabilitation has less impacts on the plateau that spontaneous biological recovery could be expected.
- Trial name
- NCT05041582
- Testing
- tDCS, Citalopram, Rehabilitation
- Volunteers
- 80 people
- Sponsor
- Chih-Wei Tang
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Good Limb Position Management Assistive Devices on Preventing Shoulder Subluxation in Hemiplegic Patients
Stroke is a leading cause of long-term disability worldwide. During the early stage of recovery after cerebral infarction, reduced muscle tone and muscle weakness in the affected upper limb may lead to shoulder instability and…
- Trial name
- NCT07675759
- Testing
- Commercially Available Shoulder Sling, Novel Shoulder Subluxation Prevention Orthosis
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebrolysin
Effects of Cerebrolysin on Motor Recovery in Patients With Subacute Stroke
This study, E-COMPASS is a phase IV clinical trial designed as a multicenter, randomized, double-blind, placebo-controlled, parallel-group study.
- Trial name
- E-COMPASS (NCT01996761)
- Testing
- porcine brain peptide (Cerebrolysin)
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Samsung Medical Center
Exercise, Metabolism
Metabolic Responses to Exercise and Recovery
Exercise benefits health through diverse metabolic processes and is central to healthy ageing. However, intense exercise also challenges the body, causing cellular damage that must be repaired.
- Trial name
- NCT06088108
- Testing
- Cornell treadmill exercise protocol
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London