Clinical trials: Motor Recovery, active
Lumbosacral Radiculopathy, Sciatica
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy.
- Conditions
- Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar
- Trial name
- Move-MORE (NCT07125027)
- Testing
- Move-MORE
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Stroke
Interaction Between the Brain Hemispheres - Key to Motor Recovery After Stroke
Rationale: Acute stroke leaves many patients with functional deficits, of which upper extremity motor impairment is one of the most disabling.
- Trial name
- InterAct (NCT06381388)
- Testing
- cTBS
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jord Vink
Post-partum, Women
Creatine for Recovery and Thinking in Mothers
The purpose of this randomized, double-blind, parallel-group trial is to compare the effects of two doses of creatine monohydrate (5 g/day versus 10 g/day) administered for four weeks in postpartum women.
- Trial name
- CREATE-MOM (NCT07795853)
- Testing
- Creatine Monohdyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Good Limb Position Management Assistive Devices on Preventing Shoulder Subluxation in Hemiplegic Patients
Stroke is a leading cause of long-term disability worldwide. During the early stage of recovery after cerebral infarction, reduced muscle tone and muscle weakness in the affected upper limb may lead to shoulder instability and…
- Trial name
- NCT07675759
- Testing
- Commercially Available Shoulder Sling, Novel Shoulder Subluxation Prevention Orthosis
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Chronic Stroke Patients
RESPARK - Brain Q for Chronic Stroke
This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers non-invasive…
- Conditions
- Stroke, Chronic Stroke Patients, Cerebrovascular Accident (CVA)
- Trial name
- NCT07095920
- Testing
- Device: Q Therapeutic System (BQ 3.0) - Active
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Stroke
Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence.
- Trial name
- CN-NINM (NCT06386510)
- Testing
- Strength training, Cranial nerve non-invasive neuromodulation
- Where
- 3 sites in Canada
- Volunteers
- 74 people
- Sponsor
- Université de Sherbrooke
Stroke
Sleep and Motor Learning in Stroke
This study will explore whether sleep disruption in the sub-acute phase of stroke explains variation in clinical motor outcomes, and whether this relationship is mediated by variation in behavioural measures of overnight…
- Trial name
- SMiLES (NCT05746260)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Obesity
Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters
The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise.
- Trial name
- NCT06579508
- Testing
- Cycle ergometer
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stroke, Upper Extremity Paresis
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke
Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily…
- Trial name
- RIITSTROKE (NCT07598435)
- Testing
- Rhythmic Initiation (PNF technique), Isometric Resistance Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Gait, Unsteady
At-home Walking Cadence Functional Assessment and Recovery Trajectory for Older Adults Undergoing Major Surgery
This is a prospective observational study looking at gait-cadence in older adults who are scheduled to have major abdominal surgery at the University of Chicago.
- Trial name
- CADENCE (NCT05886725)
- Testing
- Patients using Step Test Application and Accelerometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Stroke
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA.
- Trial name
- NCT07113990
- Testing
- Active EA, Active rTMS
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Jing Tao
Gestational Diabetes
Usability Study of the Sensors and eMOM GDM Application
The principal aim of the eMOM GDM-project is to evaluate the effect of the eMOM GDM -application and the integrated service concept model on maternal and neonatal outcomes.
- Trial name
- eMOMGDM (NCT03941652)
- Where
- Finland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Neuropathic Pain Management
tACS for Neuropathic Pain Management After SCI
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
- Trial name
- NCT06029075
- Testing
- tACS 10Hz, tACS 20Hz
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ictus, Stroke
Motor and Cognitive Telerehabilitation in a Virtual Environment in Patients With Post-stroke Sequelae and Parkinson's Disease
The goal of this interventional pilot trial is to evaluate whether a telerehabilitation protocol based on immersive virtual reality (VR) is effective and feasible for the recovery of cognitive and/or motor functions in patients…
- Conditions
- Ictus, Stroke, Parkinson Disease
- Trial name
- HOME VR REHAB (NCT07582497)
- Testing
- VR-based Telerehabilitation with Home Kit, Standard Rehabilitation (Conventional Care)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Usl di Bologna
Brain Diseases, Central Nervous System Diseases
Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke
Following a stroke, the function of the distal upper limb, especially hand and finger movements, is often severely compromised, significantly restricting the ability to carry out daily activities.
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Stroke
- Trial name
- bi-tDCS+VR (NCT07288385)
- Testing
- Transcranial Direct Current Stimulation combined with virtual reality
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Saud University
Motor Impairment, Motor Impairments
Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke
This study will evaluate the effects of transcutaneous vagus nerve stimulation in combination with physical rehabilitation on upper limb motor function of patients with stroke.
- Conditions
- Motor Impairment, Motor Impairments, Stroke, Stroke; Sequelae
- Trial name
- INPULSE (NCT06895005)
- Testing
- Transcutaneous auricular vagus nerve stimulation + rehabilitation therapy
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli