Clinical trials: Motor Speech
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Stuttering, Adult, Stuttering, Childhood
Transcranial Alternating Current Stimulation (tACS) in Stuttering
The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that…
- Conditions
- Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06740968
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Stroke, Aphasia
Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Aphasia is a language disorder that affects oral and written expression and/or comprehension. It's one of the most disabling consequence of stroke.
- Trial name
- MOTOLANG-AVC (NCT05776368)
- Testing
- Syntactic comprehension battery (BCS), Montreal Cognitive Assessment (MOCA), Purdue Pegboard Test
- Where
- 3 sites in France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
ALS, Amyotrophic Lateral Sclerosis
Speech Analysis in ALS Patients
The purpose of this study is to find out if changes in speech can signal changes in the ability to think or remember. ALS patients with and without cognitive dysfunction will be followed for one year.
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Lou Gehrig Disease
- Trial name
- NCT03868345
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Barrow Neurological Institute
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Speech Sound Disorder
Visual-acoustic Intervention With Service Delivery In-person and Via Telepractice Trial
Children with speech sound disorder show diminished intelligibility in spoken communication and may thus be perceived as less capable than peers, with negative consequences for both socioemotional and socioeconomic outcomes.
- Trial name
- VISIT (NCT06517225)
- Testing
- Visual-acoustic biofeedback
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- New York University
Specific Developmental Disorders of Speech and Language, Specific Learning Disorder
Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
To evaluate, in primary care, the sensitivity of Heterophory-Vertical-Labile (HV-Labile) in ambulatory screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
- Conditions
- Specific Developmental Disorders of Speech and Language, Specific Learning Disorder, Dyslexia, Developmental, Developmental Coordination Disorder
- Trial name
- TDys (NCT04122820)
- Testing
- Diagnostic of specific learning disabilities or of Developmental Coordination Disorder
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- CNGE IRMG Association
Amyotrophic Lateral Sclerosis, Motor Neurone Disease
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
Amyotrophic Lateral Sclerosis (ALS), the most common form of Motor Neuron Disease (MND), is a neurodegenerative disease. At present there are limited treatment options for this disease which progressively affects physical…
- Trial name
- TechnicALS (NCT06820008)
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University of Dublin, Trinity College
Speech, Motor Activity
Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning
These studies test the hypothesis that frontal areas of the brain participate in the cortical networks involved in the somotosensory processing that happens during speech motor learning.
- Trial name
- BRAVA² (NCT04547569)
- Testing
- Speech adaptation, Vibrotactile Discrimination, fMRI
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stuttering, Developmental
Investigating Non-invasive Brain Stimulation to Enhance Fluency in People Who Stutter
This study aims to test whether the application of transcranial direct current stimulation (tDCS) concurrent with fluency training results in improvements in speech fluency in adults with developmental stuttering, measured up to…
- Trial name
- INSTEP (NCT03335722)
- Testing
- Metronome-timed speech, Active tDCS
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Stroke, Aphasia
MIT Intensive Treatment Study
This study is examining the use of intensive melodic intonation therapy and video feedback as a means of aiding individuals with nonfluent aphasia and co-occurring motor speech impairments.
- Conditions
- Stroke, Aphasia, Motor Speech
- Trial name
- MITTXS (NCT06213376)
- Testing
- Melodic Intonation Therapy, Video Feedback Performance Review
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Nevada State University
Developmental Articulation Disorder, Stuttering
Study of Brain Activity During Speech Production and Speech Perception
The purpose of this study is to gain a better understanding of the brain's activity and organization in the development of speech disorders.
- Trial name
- NCT00004991
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Psychosis, Schizophrenia Disorders
HYEEG Discourse in Psychosis: A Neurobehavioural Study
This multimodal study explores the mechanisms underlying social dysfunction in individuals with schizophrenia. It focuses on the relationship between disorganized communication and social interaction, aiming to identify…
- Trial name
- DISCOURSE-NB (NCT06978803)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Parkinson's Disease
Measures of Motor Impairment in Early Parkinson's Disease
This study will test the accuracy of a new home-use electronic device that measures and records small changes in Parkinson's disease symptoms, such as tremor and impaired movement and speech.
- Trial name
- NCT00291265
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Aphasia Non Fluent, Stroke
Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke Aphasia
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that…
- Trial name
- SEMO (NCT04433351)
- Testing
- Enriched rehabilitation, Simple rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Stroke, Motor Speech Disorder
Speech Rehabilitation Based on Mobile Applications
This study evaluates the efficacy of smartphone-based speech therapy administered at home compared with usual care. Participants will be randomized into the treatment and waitlist control groups with an allocation ratio of 1:1.
- Trial name
- NCT06592183
- Testing
- Smart-phone based, self-driven speech rehabilitation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Florida State University
Aphasia, Acquired, Aphasia
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
- Trial name
- NCT06185023
- Testing
- Low-intensity physical exercise, High-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, Berkeley
Stroke, Oral Motor Functions
ORal-motor Assessment and Rehabilitation Mobile App (ORAR App)
The goal of this study is to set up a database of oral-motor and speech functions of post-stroke patients in Hong Kong via an artificial intelligence-powered mobile-health application. The main study objectives are: 1.
- Trial name
- ORAR (NCT06635187)
- Testing
- Speech and swallowing assessment
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Speech Sound Disorder
staRt: Enhancing Speech Treatment With Smartphone-delivered Biofeedback
Previous research suggests that biofeedback can outperform traditional interventions for RSE, but no controlled studies have tested this hypothesis in the context of app-delivered biofeedback.
- Trial name
- staRt (NCT04474691)
- Testing
- Traditional articulation treatment, Visual-acoustic biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University
Corticobasal Syndrome, Progressive Supranuclear Palsy
Diagnosing Frontotemporal Lobar Degeneration
To establish diagnostic tools to make an accurate clinical and pathological diagnosis of patients with clinical FTLD syndromes
- Conditions
- Corticobasal Syndrome, Progressive Supranuclear Palsy, Behavioral Variant Frontotemporal Dementia, Semantic Dementia
- Trial name
- NCT02964637
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto