Clinical trials: Mouthwashes
Coronavirus Infection
SINUS WASH Pilot Study in Adults Testing Positive for COVID-19
COVID-19 is highly infectious and transmission of the virus is thought to be similar to that of influenza which can be transferred through droplets released when a person coughs, sneezes or talks.
- Trial name
- NCT04393792
- Testing
- Povidone-Iodine, Normal saline
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Acute Leukemia, Acute Myeloid Leukemia
Prevention of Oral Mucositis in Adults in With Hematologic Malignancy
The goal of this quasiexperimental cohort controlled intervention study is to learn if aloe vera mouthwash works better than usual care in the prevention and treatment of oral mucositis.
- Conditions
- Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Oral Mucositis
- Trial name
- NCT07809984
- Testing
- Aloe Vera Mouthwash, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wake Forest University Health Sciences
Sensitive Gum, Gum Inflammation
Usage Test on a New Cosmetic Product: Mouthwash
The goal of this clinical trial is to learn if a new mouthwash can help soothing oral mucosa in adult patients with sensitive gums.
- Trial name
- NCT06808711
- Testing
- Buccocéan mouthwash, Marketed mouthwash
- Where
- France
- Volunteers
- 50 people
- Sponsor
- YSLab
Tooth Extraction Site Healing
Topical Analgesic Versus Saline Mouth Rinses in Post Extraction Healing
There is no evidence based guidelines on using saline rinses for post extraction oral care among hypertensives. Similarly, benefit of orally dissolved topical analgesics in addition to orally administered analgesic is…
- Trial name
- NCT03130153
- Testing
- Aspirin Powder, Normal saline
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Aga Khan University
Diabetes Type 2, Periodontitis
Exploratory Study of Iocide Oral Rinse in a Diabetic Population
The goals of this exploratory study are to 1)examine an investigational oral rinse as an adjunctive agent to scaling and root planing in treating chronic periodontitis in a periodontitis-susceptible diabetes population, and 2)…
- Trial name
- Diabetes (NCT00801164)
- Testing
- Frio Mouth Rinse
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biomedical Development Corporation
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Oral Mucositis
Coconut Oil to Prevent Mouth Sores in Pediatric Patients Receiving High Dose Chemotherapy
The purpose of this study is to learn if virgin coconut oil (VCO) mouth rinse can help prevent oral mucositis. The Study Investigator will compare standard of care mucositis prevention rinses with the VCO mouth rinse added to the…
- Trial name
- NCT05441813
- Testing
- Virgin Coconut Oil
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Dentin Sensitivity
A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity
To investigate the efficacy of an experimental oral rinse, containing 1.5% potassium oxalate (KOX) and 0 parts per million (ppm) fluoride in relieving dentine hypersensitivity (DH) after 8 weeks use compared with a placebo oral…
- Trial name
- NCT03238352
- Testing
- Potassium oxalate, Sodium fluoride
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Halitosis
Evaluation of Clinical and Cost-effectiveness of Different Mouthwashes on Controlling Halitosis Among a Group of Egyptian Children
To evaluate the clinical and cost-effectiveness of mouthwash containing Curcuma longa (Turmeric extract) versus mouthwash containing essential oils and Placebo mouthwash on controlling Halitosis among a group of Egyptian children.
- Trial name
- NCT04905940
- Testing
- Turmeric mouthwash
- Volunteers
- 30 people
- Sponsor
- Cairo University
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stomatitis
Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer
Oral mucositis is a debilitating side effects of cancer treatment for which there is not much successful treatments at yet. The investigators are going to evaluate the effectiveness of topical morphine compared with a routine…
- Trial name
- NCT01837446
- Testing
- 2% morphine solution, Magnesium aluminum hydroxide, 2% viscous lidocaine
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Isfahan University of Medical Sciences
Oral Bacteria Levels in the Mouth
The Efficacy of Sesewanua (Clerodendrum Fragrans Wild) Mouthwash in Reducing Oral Bacteria Growth: A Quasi-Experimental Study in Nursing Practice
Background and Objectives: This study investigated the antibacterial efficacy of Sesewanua (Clerodendrum fragrans Wild) extract as a mouthwash alternative to mitigate oral bacteria, particularly Streptococcus mutans.
- Trial name
- NCT07434882
- Testing
- 1% sesewanua extract mouthwash Arm, 2% sesewanua extract mouthwash, 4% sesewanua extract mouthwash Arm
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Poltekkes Kemenkes Manado
Healthy
A Randomized, Comparative Study to Evaluate the Effect of RL3014A-DP0421 Mouthwash on the Oral Microbial Composition
The Laboratoires Pierre Fabre has on the market a product range of daily use mouthwash, all containing 0.05% of O-Cymen -5-ol, a broad-spectrum bactericide.
- Trial name
- NCT07685782
- Testing
- RL3014A - DP0421, CO3014AZ, CO3014AY
- Where
- Poland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Healthy
A Study of Virtually Supervised Mouth Rinses and Flossing
The purpose of this study is to evaluate the efficacy of brushing, flossing, and rinsing with essential oil mouth rinses; brushing and flossing; versus brushing and rinsing with essential oil mouth rinses; and brushing only for…
- Trial name
- NCT05600231
- Testing
- LISTERINE COOL MINT Antiseptic Mouthwash, LISTERINE COOL MINT ZERO Alcohol Mouthwash, Reach Unflavored Waxed Dental Floss
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Hypochlorous Acid, Mouthwashes
HYPOCHLOROUS ACID SUBSTANTIVITY AS ANTIPLAQUE AGENT (HOCl-SAP)
Hypochlorous acid (HOCl) in a non-antibiotic antimicrobial agent used in clinical medicine. Nevertheless, its antiplaque oral effect has not been evaluated.
- Trial name
- HOCl-SAP (NCT03174756)
- Testing
- Hypochlorous Acid, Chlorhexidine
- Where
- Colombia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Performance, Soccer
Carbohydrate Mouth Rinse (Small-Sided Soccer Games)
The present study evaluated the influence of carbohydrate mouth-rinsing (CHO- MR) and placebo (PLA) conditions on the psychophysiological responses, kinematic profiles, and technical performance of young male soccer players in…
- Conditions
- Performance, Soccer, Carbohydrate, Mental Fatigue
- Trial name
- CHOMR-SSGs (NCT06990022)
- Testing
- Carbohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dentine Hypersensitivity
A Study to Evaluate the Dentinal Hypersensitivity Efficacy of Two Experimental Mouthwash Formulations
The aim of this study is to evaluate the clinical efficacy of two experimental mouthwash formulations, against a placebo mouthwash (without experimental ingredients).
- Trial name
- NCT07741032
- Testing
- 3% KNO3 Mouthwash, 2% HPC Mouthwash, 0% KNO3 Mouthwash
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- HALEON
Orthodontic Appliance Complication, Halitosis
Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
The aim of this trial was to investigate the effect of Cotinus Coggygria mouthwash on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents…
- Trial name
- NCT07254819
- Testing
- Cotinus Coggygria mouthwash
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Athens
Hospital-acquired Pneumonia
0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
Chlorhexidine is a effective strategy in reducing ventilator associated pneumonia. However, it is unclear if prophylactic 0.12% chlorhexidine oral rinse can reduce the risk of non-ventilator hospital-acquired pneumonia among…
- Trial name
- NCT04403971
- Testing
- 0.12% Chlorhexidine Oral Liquid Product, Listerine Oral Liquid Product, Normal Saline Product
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- National Cheng-Kung University Hospital