Clinical trials: Movement Abnormalities
Parkinson's Disease
Evaluation of the Role of the Noradrenergic System in Pain Perception in Parkinson's Disease
Patients suffering from Parkinson's disease (PD) frequently experienced painful sensations that could be, in part, due to a central modification of nociception mechanisms.
- Trial name
- DOULOX (NCT01504178)
- Testing
- duloxetine, injection of apomorphine, L-Dopa
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Toulouse
Parkinson's, Alzheimer Disease
Sound Estimation and Accuracy Task
Participants will be assigned to complete computerized estimation tasks for which there is a component of accuracy, such as estimating the duration of sounds.
- Trial name
- NCT02271685
- Testing
- Instructions about Overestimates, Instructions about Parkinson's, Instructions about Underestimates
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Parkinson's Disease and Parkinsonism
Personalized rTMS Protocol Based on Functional Reserve to Enhance Ambulatory Function in PD Patients
The objective of this study was to determine the effects of protocols of repetitive transcranial magnetic stimulation (rTMS) therapy based on the functional reserve of each patient with Parkinson's disease, compared to…
- Trial name
- NCT06350617
- Testing
- High-Frequency, ipsilateral M1, High-Frequency, bilateral M1, High-Frequency, Lt. DLPFC
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Deep Neural Network Approaches for Closed-Loop Deep Brain Stimulation
In this research study the researchers want to learn more about brain activity related to speech perception and production in patients with Parkinson's Disease who are undergoing deep brain stimulation (DBS).
- Trial name
- NCT04277689
- Testing
- Brain signal data collection
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Parkinson's Disease
Development of a Fall Prevention and Fall Detection System for Ambulatory Rehabilitation of Parkinson's Patients
The investigators plan to conduct a first-stage experiment by recruiting ten subjects, including five PD patients and five non-PD patients.
- Trial name
- NCT01262950
- Testing
- portable motion detector
- Sponsor
- Far Eastern Memorial Hospital
Alzheimer Disease, Parkinson Disease
An Exploratory Study to Confirm Efficacy of Modified Deep Cervical Lymphovenous Anastomosis (LVA) in Alzheimer's Disease/ Parkinson's Disease
Alzheimer's disease (AD) and Parkinson's disease (PD) are characterized by pathological protein accumulation in the brain-Aβ/tau in AD and α-synuclein in PD.
- Trial name
- SOLVEN (NCT06852352)
- Testing
- Modified deep cervical Lymphatic-Venous Anastomosis
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Zhejiang Provincial People's Hospital
Lewy Body Disease, Healthy Aging
Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment
Lewy body diseases (LBDs) represents a group of neurodegenerative disorders characterized by the abnormal accumulation of aggregates of α-synuclein protein leading to the formation of Lewy bodies (LB) and Lewy neurites resulting…
- Trial name
- LANG-LBD (NCT05847985)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Tic Disorder
Scalp Acupuncture Treatment for Chronic Tic Disorders in Children
The goal of this clinical trial is to learn if scalp acupuncture works to treat chronic tic disorders (CTD) in children. It will also learn about the safety of scalp acupuncture.
- Trial name
- NCT06924918
- Testing
- Scalp Acupuncture Treatment, Tuina Treatment Group
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Children's Hospital of Fudan University
Parkinson Disease
Effects of Sensory Integration Training on Balance and Confidence in Patients With Parkinson's Disease
The Objective of this research was to study the effectiveness of sensory integration training on balance and confidence in patients with Parkinson's disease.
- Trial name
- NCT05907148
- Testing
- Sensory integration training, Routine physical therapy, General coordination exercise
- Where
- 2 sites in Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Essential Tremor
Algorithms for Programming DBS Systems for ET
Deep brain stimulation (DBS) targeting the Vim thalamus (ventralis intermedius nucleus) is an FDA-approved neuromodulation therapy for treating postural and action tremor in individuals with essential tremor (ET).
- Trial name
- NCT03984643
- Testing
- Vim-Deep Brain Stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Minnesota
Limb Dystonia, Idiopathic Dystonia
Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia
The goal of this clinical trial is to find out if a non-invasive procedure called focused ultrasound can safely and effectively treat limb dystonia in adults who have not improved with medications or botulinum toxin injections.
- Conditions
- Limb Dystonia, Idiopathic Dystonia, Medication-refractory Dystonia, Dystonia, Focal
- Trial name
- FUTURE (NCT07168850)
- Testing
- Exablate MR-guided Focused Ultrasound Pallidotomy
- Where
- 4 sites in Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Parkinson Disease
Pilot Study on the Effects of IMOOVE in Parkinson's Disease Patients
Parkinson's Disease (PD) is one of the most frequent causes of motor dysfunction in aging. It is therefore important to use rehabilitative therapeutic approaches that may prevent the development of motor complications when…
- Trial name
- IMOOVE-PD (NCT04568447)
- Testing
- IMOOVE
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- IRCCS San Raffaele Roma
Parkinson Disease
Effects of Home-based High-speed Bodyweight Resistance Training in Individual With Parkinson's Disease
Exercises that involve increasing the speed of movements are beneficial for individuals with Parkinson's disease (PD) and have the potential to reduce bradykinesia and improve mobility.
- Trial name
- NCT06646523
- Testing
- High-speed bodyweight resistance training, Control group (Bodyweight intervention, usual speed)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Federal University of Minas Gerais
Essential Tremor
Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)
To compile characteristics of real-world outcomes for Boston Scientific Corporation's commercially approved Deep Brain Stimulation (DBS) Systems, when used according to the applicable Directions for Use, for the treatment of…
- Trial name
- NCT04032470
- Testing
- Deep Brain Stimulation Systems (DBS)
- Where
- 20 sites in Austria, Belgium and 7 more
- Volunteers
- 500 people
- Sponsor
- Boston Scientific Corporation
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson Disease
Intrapatient Comparison of STN and GPi tTIS in PD
The goal of this clinical trial is to investigate the therapeutic efficacy of tTIS in patients with Parkinson's disease and to evaluate the immediate effects and conduct intrapatient comparisons of individualized 130 Hz…
- Trial name
- NCT07018388
- Testing
- NervioX-2400
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Parkinson's Disease
The Therapeutics Effects of Yoga in Individuals With Parkinson's Disease
To determine if yoga is beneficial in improving physical function quality of life and medical status in people with Parkinson's disease
- Trial name
- NCT00312559
- Testing
- Yoga Training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Kansas
OSA, Proteinuria
The Association Between Sleep Duration and Sleep Disorders and Proteinuria in Children
The presence of protein in urine is a common laboratory finding in children. Although proteinuria is usually benign, it can be a marker of a serious underlying renal disease or systemic disorder.
- Conditions
- OSA, Proteinuria, Periodic Limb Movement Sleep Disorder
- Trial name
- NCT03933046
- Testing
- PSG
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Bringing Parkinson Care Back Home
SUMMARY Rationale: For persons with Parkinson's disease (PD), medical decisions are based almost exclusively on periodic in-clinic evaluations by a neurologist or a nurse.
- Trial name
- NCT04288583
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Parkinson Disease
Effects of a Treadmill Gait Training Protocol in a Gamified Virtual Reality Environment With tDCS in Parkinson's Disease
The study aims to compare the effects of treadmill gait training in a gamified virtual reality environment with tDCS versus treadmill gait training in a gamified virtual reality environment versus treadmill training in people…
- Trial name
- NCT05243394
- Testing
- Gamified virtual reality treadmill gait training with tDCS, Gamified virtual reality treadmill gait training, Treadmill gait training
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universitat de Lleida
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