Clinical trials: Movement Abnormalities
Drug-Induced Movement Disorder
Evaluating a Telemedicine Neurological Consult Program for Drug-Induced Movement Disorders Using the RE-AIM Framework
In this pilot study, the investigators will evaluate care delivery via telemedicine to individuals with drug-induced movement disorders (DIMDs).
- Trial name
- NCT06060444
- Testing
- Telemedicine Consult, In-person Consult
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Vermont
Idiopathic Parkinson's Disease
Efficacy and Safety Study of Inhaled CVT 301 in Parkinson's Disease Patients for Treatment of OFF Episodes
This randomized, multicenter, placebo-controlled, double-blind study will evaluate the efficacy and safety of inhaled CVT 301 compared with placebo in PD patients experiencing motor response fluctuations (OFF phenomena) as an…
- Trial name
- NCT01777555
- Testing
- CVT-301
- Where
- 22 sites in United States, Italy and 2 more
- Volunteers
- 89 people
- Sponsor
- Acorda Therapeutics
Parkinson Disease, Healthy Volunteer
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
The research study is being conducted to test how a specialized type of Positron Emission Tomography (PET/CT) scan could potentially be useful in diagnosing or monitoring treatment in people with Parkinson's disease.
- Trial name
- NCT04062526
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Parkinson's Disease
ADAGIO Follow Up Study: Evaluation of the Long-Term Effects of Rasagiline in Parkinson's Disease Subjects
Eligible participants, who participated in the ADAGIO trial and who sign an approved informed consent form, will be enrolled into the study at their original study locations.
- Trial name
- NCT00936676
- Testing
- rasagiline mesylate
- Where
- 102 sites in United States, Argentina and 11 more
- Volunteers
- 684 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Parkinson
The Effect of Deep Brain Stimulation on Facial Expressions.
Whether Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS), a treatment commonly used to ameliorate the motor symptoms of Parkinson's disease (PD), affects on facial expressions is unclear.
- Trial name
- STN-DBS (NCT03558568)
- Testing
- Deep Brain Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Parkinson Disease
Core Stability and Parkinson Disease
Patients with Parkinson's Disease frequently present impaired postural control that leads to loss of stability and increased risk of falls.Core system, includes passive structures of the thoracolumbar spine and pelvis that work…
- Trial name
- NCT03580096
- Testing
- Core stability, Standard intervention
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad de Granada
Parkinson Disease
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
The primary purpose of this study is to evaluate efficacy and safety of CREXONT under real world conditions in participants with Parkinson disease (PD).
- Trial name
- NCT06765668
- Testing
- CREXONT ER
- Where
- 27 sites in United States
- Volunteers
- 220 people
- Sponsor
- Impax Laboratories, LLC
Parkinson Disease
SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease
With this study, the investigators want to investigate whether computerized speech analysis can be used to reliably and objectively detect motor, emotional, and cognitive fluctuations in Parkinson's disease patients.
- Trial name
- EMO-SPEECH-PD (NCT05765110)
- Testing
- Dopaminergic OFF drug state, DBS OFF state, Dopaminergic ON drug state
- Where
- 2 sites in Czechia, Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Alzheimer's Disease, Huntington Disease
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
This study will evaluate four different modified release formulation to estimate the amount of dimebon available to the body relative to the current dimebon formulation that is given three times a day.
- Trial name
- NCT00988624
- Testing
- Dimebon IR Tablet, Dimebon MR1, Dimebon MR2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Movement Disorders, Neurology
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications
This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years.
- Conditions
- Movement Disorders, Neurology, Parkinsons Disease
- Trial name
- NCT05539196
- Testing
- Exablate Pallidotomy, Unilateral
- Where
- 5 sites in United States, Japan
- Volunteers
- 60 people
- Sponsor
- InSightec
Parkinson's Disease
Efficacy of a Recreation Therapy Wellness Recovery Program for Individuals With Parkinson's Disease
The Recreation Therapy Wellness Recovery Program conducts group classes which provide repetitive training of foundational skills designed specifically for those with Parkinson's Disease.
- Trial name
- NCT04164043
- Testing
- Wellness Recovery Program
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Parkinson's Disease
Cough According to Stimulus Type in PD
Aspiration pneumonia (APn) occurs at a higher rate in patients with Parkinson's disease (PD) versus healthy adults. This is of particular public health concern given that death secondary to aspiration pneumonia and lung infection…
- Trial name
- NCT02390089
- Testing
- Capsaicin vapor, fog, Videofluoroscopic swallow evaluation
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alzheimer Dementia, Dementia, Vascular
Tailored Music Therapy for Dementia
This study evaluates the effect and process of individualized music therapy for home-dwelling persons with mild to moderate dementia. The music therapy is administered individually and includes a close caregiver.
- Conditions
- Alzheimer Dementia, Dementia, Vascular, Dementia, Lewy Body, Dementia Parkinson's Disease
- Trial name
- NCT03011723
- Testing
- Resource oriented music therapy
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- University of Bergen
Parkinson's Disease
How Does STN-DBS Influence Emotional Conflict Decision in Parkinson's Disease: a EEG Study
A large body of evidence points to impairment in the decoding of emotional stimuli in Parkinson's disease (PD). These changes seem to be related to dysfunction of the mesocorticolimbic projections leading to dysfunction of the…
- Trial name
- DBS-EMOTION (NCT02786680)
- Testing
- stroop test in condition DBS off, stroop test in condition DBS on
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Parkinson's Disease
Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Motor Fluctuations
The primary objective of the study is to assess the efficacy, carbidopa dose response and safety of ODM-101, a new combination of levodopa, carbidopa and entacapone in the treatment of Parkinson's disease (PD) patients with…
- Trial name
- PARPOC (NCT01766258)
- Testing
- ODM-101 65mg Carbidopa, ODM-101 105mg Carbidopa, Stalevo
- Volunteers
- 117 people
- Sponsor
- Orion Corporation, Orion Pharma
Parkinson Disease, Dementia
Combined Subthalamic and Nucleus Basalis Meynert Deep Brain Stimulation for Parkinson's Disease With Dementia
Phase 1 study evaluating the safety of combined bilateral subthalamic nucleus (STN) and basal nucleus of Meynert (NBM) stimulation in treating levodopa responsive motor symptoms of Parkinsonism and cognitive dysfunction in…
- Trial name
- Dempark-DBS (NCT02589925)
- Testing
- Vercise deep brain stimulation, subthalamic nucleus (STN) stimulation, NBM stimulation
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Wuerzburg University Hospital
Progressive Supranuclear Palsy, Parkinson's Disease
Postural Instability in Progressive Supranuclear Palsy
The purpose of this study is to better understand why individuals with Progressive Supranuclear Palsy (PSP) fall. Understanding the mechanism of gait and balance dysfunction in individuals with PSP may provide us with important…
- Trial name
- NCT01563276
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson Disease, Freezing of Gait
Understand FoG in PD: Behavioral Physiology and Clinical Application
The overall goals of this proposed study are to investigate the behavioral and neurophysiological mechanisms of patients with Parkinson's disease (PD) experiencing freezing of gait (FoG).
- Trial name
- NCT02987140
- Testing
- Clinical evaluations
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tourette Syndrome
Observational Database on Deep Brain Stimulation in Tourette Syndrome
Within an ongoing deep brain stimulation (DBS) program for Tourette syndrome (TS) at the Department of Neurology, Pitié-Salpêtrière Hospital, Paris/France, the investigator team plans to evaluate patients pre-operatively and then…
- Trial name
- POSTSTIC (NCT04449068)
- Testing
- Neurological and neuropsychological Follow-up after deep brain stimulation, EEG recordings
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia, Autism Spectrum Disorder
Cerebellar Stimulation and Cognitive Control
The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autism, bipolar disorder, Parkinson's disease, and major depression.
- Conditions
- Schizophrenia, Autism Spectrum Disorder, Bipolar Disorder, Depression
- Trial name
- NCT03217110
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Krystal Parker, PhD
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.