Clinical trials: Movement Abnormalities
Parkinson Disease, Healthy
Rapid dEvice Testing pROtocol for Parkinson's Disease
This is an 8 week observational study to evaluate the feasibility of using remote monitoring technologies in future studies of PD.
- Trial name
- RETRO-PD (NCT04675853)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HealthMode Inc.
Parkinson Disease
The Alouette Test in Parkinson Disease
Reading disorders in Parkinson's Disease (PD) are poorly evaluated due to the lack of validated tests to screen for them. They are often attributed to hand tremors associated with the disease.
- Trial name
- REPEAT (NCT03958175)
- Testing
- Alouette test (reading test)
- Volunteers
- 38 people
- Sponsor
- Hospices Civils de Lyon
Dementia Associated With Parkinson's Disease, Dementia With Lewy Bodies
Efficacy and Safety of Memantine for Parkinson's Disease Dementia (PDD) and Dementia With Lewy Bodies (DLB)
A 24-week placebo-controlled parallel group multicentre trial to study the safety and efficacy of memantine in patients with dementia associated with Parkinson's disease and dementia with Lewy bodies.
- Trial name
- MEMPDD (NCT00630500)
- Testing
- Memantine
- Where
- 4 sites in Norway, Sweden and 1 more
- Volunteers
- 75 people
- Sponsor
- Helse Stavanger HF
PARKINSON DISEASE (Disorder), Falls Prevention
Home-Based Exercise Programs for Fall Prevention in Parkinson Disease
Falls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury.
- Conditions
- PARKINSON DISEASE (Disorder), Falls Prevention, Exercise
- Trial name
- NCT07590700
- Testing
- Otago Home Exercise Program, Structured Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Uludag University
Parkinson's Disease
Gait Characteristics and Cognitive Evolution in Parkinson Disease
Parkinson's disease (PD) is a chronic progressive nervous system disease with gradual motor impairment. Cognitive dysfunction is common in PD, even in the early stages, and it is characterized by impairments in executive…
- Trial name
- GECO-PD (NCT04297800)
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Huntington Disease
Benchmarking Integrated Care for People Living With Huntington's Disease in England
The survey and full study information can be accessed here: https://southampton.qualtrics.com/jfe/form/SV_8iEedDJZy4xaiI6 The goal of this anonymous survey is to benchmark integrated care from the perspective of service users in…
- Trial name
- Integrate-HD (NCT05828992)
- Testing
- No intervention administered
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southampton
PARKINSON DISEASE (Disorder), Parkinsonism or Parkinson's Disease Nos
Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease
Parkinson´s disease and parkinsonian syndromes are associated with progressive motor and non-motor impairments that may compromise functional independence and quality of life.
- Trial name
- SARCOPARKINSON (NCT07907302)
- Testing
- Nutricional Education and General Exercise Guidelines, Progressive Resistance Training With Cognitive Dual-Task Training, Progressive Resistance Training With Cognitive Dual-Task and Inestability Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Valencia
Multiple Sclerosis, Epilepsy
Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation
The presence of a damage to the central and / or peripheral nervous system resulting from diseases of a different nature (such as, Multiple Sclerosis, Parkinson's disease, dementia, head trauma, stroke, epilepsy or other…
- Conditions
- Multiple Sclerosis, Epilepsy, Parkinson Disease, Dementia
- Trial name
- NCT05450237
- Testing
- Psychometric Evaluations
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Neuromed IRCCS
Parkinson Disease, Weight-Lifting Exercise Program
Daily Undulating Periodization Methods With Parkinson's Disease
Compare periodized (cyclic) resistance training with and without motor training specific to activities of daily living.
- Trial name
- NCT03867877
- Testing
- Periodized training with motor practice, Simple Periodized Training
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Parkinson's Disease
Single Dose Study to Assess the Pharmacokinetics of SCH 900800 in Subjects With Parkinson's Disease Being Treated With Levodopa (L-DOPA) (P08235)
This study is being done to assess the pharmacokinetics of SCH 900800 in participants with moderate to severe Parkinson's Disease (PD) being treated with L-DOPA.
- Trial name
- NCT01500707
- Testing
- SCH 900800
- Sponsor
- Merck Sharp & Dohme LLC
Parkinson's Disease
Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease
Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains quite poor.
- Trial name
- NCT06405334
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Essential Tremor
Transcranial Ultrasound Therapy of Essential Tremor
Context. Essential tremor (ET) is a common disease, disabling in severe forms and resistant to drug treatment. In patients with severe ET, invasive neurosurgical technique such as deep brain stimulation of the Ventral…
- Trial name
- ULTRABRAINTher (NCT04074031)
- Testing
- Transcranial Ultrasound Therapy (Exablate® 4000 Type 1.1)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinsonian Syndrome
Study of Individuals With Parkinson's Symptoms But in Whom There is Diagnostic Uncertainty
The overall goal of this study is to evaluate the use of dopamine transporter (DAT) imaging as a diagnostic tool in subjects with early parkinsonian symptoms, in whom Parkinson's disease (PD) or parkinsonian syndrome (PS) is…
- Trial name
- NCT00129675
- Testing
- [123I]ß CIT
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Institute for Neurodegenerative Disorders
Parkinson Disease, Acupuncture
Acupuncture for Management of Balance Impairment in Patients With Parkinson's Disease
This plan is to evaluate the effectiveness of scalp acupuncture, a modern acupuncture technique specialized to neurological disorders, in managing motor function and body balance for PD patients.
- Trial name
- NCT03178175
- Testing
- Acupuncture, Needle Insertion
- Where
- Taiwan
- Volunteers
- 4 people
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Parkinson Disease, Dyskinesia, Medication-Induced
Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients with Levodopa Induced Dyskinesia
The aim of the study is to determine potential anti-dyskinetic properties of CPL500036 (PDE10A inhibitor) in Parkinson disease patients suffering from levodopa Induced dyskinesia.
- Trial name
- NCT05297201
- Testing
- CPL500036 - low dose, CPL500036 - high dose
- Where
- 16 sites in Poland, Ukraine
- Volunteers
- 105 people
- Sponsor
- Celon Pharma SA
Dystonia, Focal
Motor and Non-motor Symptoms in Cervical Dystonia
In this monocenter, observational, non-interventional, prospective, open label study investigators will enrol 43 CD patients from the outpatient Movement Disorders Clinic of the Department of Human Neurosciences, Sapienza…
- Trial name
- Royal (NCT04560101)
- Testing
- botulinum toxin A
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- University of Roma La Sapienza
Wilsons Disease
sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis
The aim is to investigate macrophage activation markers and correlations to liver fibrosis in patients with Wilsons Disease. Researchers wish to investigate associations to neurologic and metabolic liver function.
- Trial name
- NCT02702765
- Testing
- Fibroscan, Ultrasound, Galactose
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- University of Aarhus
Tardive Dyskinesia
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia
The primary objective of this study is to evaluate the efficacy of NBI-1065890 compared with placebo for the treatment of tardive dyskinesia (TD) in adult participants.
- Trial name
- NCT07365462
- Testing
- NBI-1065890
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurocrine Biosciences
Parkinson Disease, Nutritional and Metabolic Diseases
Influence of Glucose on Metabolism and Clinical Symptoms of Patients With Parkinson's Disease
Many patients with Parkinson's Disease (PD) report an increased consumption of fast-acting sugars. This tendency to consume sweet, high-sugar foods occurs in some patients even before the onset of cardinal motor symptoms.
- Conditions
- Parkinson Disease, Nutritional and Metabolic Diseases, Sugar Intake
- Trial name
- PaGlu (NCT05998772)
- Testing
- Oral Glucose Tolerance Test
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Parkinson Disease
A Study Evaluating Potential Screening Tools for Detecting Parkinson Disease
This study is designed as a prospective cohort study to test the strategy of combining two biomarkers of parkinsonism, olfaction and brain imaging with a radioactively labeled drug, [123I]β-CIT , in a population of first-degree…
- Trial name
- NCT00387075
- Testing
- [123I]β-CIT and SPECT imaging, [123I]β-CIT
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
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