Clinical trials: Movement Abnormalities
Alzheimer Disease, Frontotemporal Degeneration
In Vivo PET of Synaptic Density in Cognitive Disorders
This study will compare the discriminative power of [18F]-SynVesT-1 PET and the standard-of-care [18F]-FDG PET in different cognitive disorders (Alzheimer's disease, Frontotemporal degeneration, dementia with Lewy bodies and…
- Conditions
- Alzheimer Disease, Frontotemporal Degeneration, Dementia With Lewy Bodies, Psychiatric Disorder
- Trial name
- NCT05384353
- Testing
- [18F]-SynVesT-1
- Where
- Belgium
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson's Disease, Mild Cognitive Impairment
A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support…
- Trial name
- NCT01646333
- Testing
- Memory and Problem-Solving Intervention, Supportive Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Tourette Syndrome
Gilles de la Tourette Syndrome (TS) and Seasonality
This retrospective and prospective observational study intends to evaluate the correlation between seasons and the variation of the syndromic structure of the Tourette.
- Trial name
- NCT04076852
- Testing
- Administration of questionnaires
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Parkinson's Disease
Speed of Processing Training in Patients With Parkinson's Disease and Healthy Older Adults
The purpose of this prospective, within-subject randomized cross-over design study is to determine if a computer training program (Speed of Processing Training - SOPT) improves safe pedestrian behavior in patients with…
- Trial name
- NCT02929758
- Testing
- Speed of processing training (SOPT)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease, Gait Disorders, Neurologic
Optimal Verbal Instruction to Improve Walking for PD
Background: One of the most disturbing motor symptoms in Parkinson's disease (PD) is gait disturbance. Clinicians often use various verbal instructions to correct abnormal gait patterns, and the most commonly used instruction is…
- Trial name
- NCT04315285
- Testing
- Treadmill gait training with verbal instruction
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- National Taiwan University Hospital
Parkinson's Disease, Physical Exercise
Research on the Effect and Mechanism of Aerobic Exercise on PD
This trial is expected to recruit patients with primary Parkinson's disease and give them four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism
- Trial name
- NCT04651140
- Testing
- aerobic exercise
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
PARKINSON DISEASE (Disorder)
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease.
- Trial name
- NCT07182058
- Testing
- Transcranial Electrical Stimulation Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- U: The Mind Company
Dyskinesia, Levodopa Induced Dyskinesia (LID)
ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study)
This is a multi-center, randomized, double-blind, placebo-controlled, 2-arm, parallel group study to evaluate the efficacy and safety of ADS-5102 extended release (ER) capsules, an investigational formulation of amantadine, dosed…
- Conditions
- Dyskinesia, Levodopa Induced Dyskinesia (LID), Parkinson's Disease
- Trial name
- EASE LID (NCT02136914)
- Testing
- ADS-5102
- Where
- 46 sites in United States, Canada
- Volunteers
- 126 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Stroke, Parkinson's Disease
Inpatient Physical Activity Function Through Enhanced Participation Levels in Animal-Assisted Therapy Programs
Thousands of canines are used for therapy in health care centers throughout the United States as part of a volunteer therapy team, yet little is known about the outcomes provided by these teams.
- Conditions
- Stroke, Parkinson's Disease, Muscle Weakness
- Trial name
- NCT02606006
- Testing
- Canine Animal-Assisted Therapy, Standard of Care Physical Therapy
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Parkinson's Disease
Neuroimaging Studies of Depression in Parkinson's Disease
The purpose of this study is to investigate similarities and differences in the neural pathways of depressed Parkinson's patients, non-depressed Parkinson's patients, and healthy controls using magnetic resonance imaging (MRI) of…
- Trial name
- NCT00518258
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lee Blonder
Functional Movement Disorder, Parkinson Disease
Movement Disorders and Early Maladaptive Schemas
Functional neurological disorders (FND) are neurological symptoms that cannot be explained by a lesion or related to an identified dysfunction of the central nervous system.
- Conditions
- Functional Movement Disorder, Parkinson Disease, Dystonic Disorders
- Trial name
- SCHEMAF (NCT03717376)
- Testing
- Self-questionnaire YSQ-S3 (Young Schema Questionnaire)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multiple Sclerosis, Stroke
Clinical and Instrumental Treatment's Predictors in Subjects With Neurological Diseases Using G-EO Robotic System
The aim of this work is to elaborate a statistical model to predict the effectiveness of robotic treatment in subjects with neurological diseases.
- Conditions
- Multiple Sclerosis, Stroke, Parkinson Disease, Acquired Brain Injury
- Trial name
- NCT05493514
- Testing
- Robotic Assisted Gait Training with G-EO system
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Parkinson Disease, Essential Tremor
Cortical-Basal Ganglia Speech Networks
In this research study the researchers want to learn more about brain activity related to speech perception and production.
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia
- Trial name
- NCT04286308
- Testing
- electrophysiological data collection
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Parkinson's Disease
Apomorphine Pump in Early Stage of Parkinson's Disease (EARLY-PUMP)
The aim of the study is to assess the use of the apomorphine pump in earlier stages of Parkinson' Disease (PD), when motor complications have just developed and before patients are significantly affected in their social and…
- Trial name
- EARLY-PUMP (NCT02864004)
- Testing
- Apomorphine, Best Medical Treatment
- Where
- 20 sites in France
- Volunteers
- 134 people
- Sponsor
- Rennes University Hospital
Tourette Disorder, Chronic Tic Disorder
Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Expert reviews and practice parameter papers recommend behavior therapy as a first-line intervention for youth with chronic tic disorders (CTDs) with mild-to-moderate tic severity.
- Trial name
- DCS+HRT (NCT02582515)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Parkinson Disease
Quasi-experimental Study With a Control Group to Evaluate a Psychoeducational Intervention in Parkinson's Disease Patients and Carers
The aim of this study is to evaluate the effects of a psychoeducational multidisciplinary intervention focusing on improving coping skills, the psychosocial adaptation to Parkinson's disease and the quality of life in patents and…
- Trial name
- ReNACE-PD01 (NCT03129425)
- Testing
- ReNACE Psychoeducational Intervention, General Educational Program
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Parkinson Disease, Mild Cognitive Impairment
Auditory Slow Wave Enhancement in Parkinson Disease and Mild Cognitive Impairment
The study aims to assess the efficacy of auditory slow-wave sleep (SWS) enhancement in PD patients and patients with amnestic MCI.
- Trial name
- PDMCI-TS (NCT04736017)
- Testing
- TSB Axo
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- University of Zurich
Fetal Conditions, Fetal Movement Disorder
Does a Relationship Exist Between Fetal Hiccups and Computerised Cardiotocography Parameters?
BACKGROUND: The physiological function of fetal hiccups and its correlation with fetal well-being is unexplored. No previous study examines the correlation between the maternal perception of the fetal hiccups and the antepartum…
- Trial name
- NCT04366076
- Testing
- Fetal heart rate (FHR) monitoring through computerized cardiotocography (cCTG) analysis antepartum
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Parkinson's Disease
Exercise Study For People With Parkinson's Disease
This study is designed to compare three different exercise approaches to learn which program is best for people with early and mid-stage Parkinson's disease.
- Trial name
- NCT00387218
- Testing
- Exercise, Physical therapy
- Where
- 4 sites in United States
- Volunteers
- 170 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Parkinson Disease
A Study to Assess Pharmacokinetics (PK) of Preladenant in Participants With Chronic Renal Impairment (CRI) (P06512)
This is a two part study to compare the PK of preladenant administered to participants with CRI to the PK of preladenant administered to healthy participants.
- Trial name
- NCT01323855
- Testing
- Preladenant
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
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