Clinical trials: Movement Abnormalities
Neurologic Disorders
Evaluation and Treatment of Neurosurgical Disorders
Objective: This protocol is designed to allow the Surgical Neurology Branch to evaluate and treat the neurosurgical disorders of protocol participants.
- Trial name
- NCT00060541
- Testing
- Laboratory tests, Radiological exams
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
PARKINSON DISEASE (Disorder), Atypical Parkinsonism
Early Molecular Biomarkers for Differentiating Parkinsonian Syndromes
This prospective observational study aims to identify and preliminarily validate molecular biomarkers, including microRNAs and metabolites, for the early differentiation of Parkinson's disease (PD) from atypical parkinsonian…
- Conditions
- PARKINSON DISEASE (Disorder), Atypical Parkinsonism, Multiple System Atrophy, Progressive Supranuclear Palsy (PSP)
- Trial name
- BIOMARK-PS (NCT07604883)
- Where
- 2 sites in Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- International Institute of Molecular and Cell Biology in Warsaw
Alzheimer Disease, Early Onset, Parkinson Disease
Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity
The aim of the NODAL clinical trial is to demonstrate the feasibility of new, low-cost, non-invasive biomarkers of neurodegenerative pathologies as early Alzheimer and Parkinson, based on the estimation of the multimodal…
- Trial name
- NODAL (NCT06080659)
- Testing
- fMRI, CONFMEM
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
"Alzheimer's Disease" and "Lewy Body Disease"
Alpha-synuclein in Cerebrospinal Fluid to Differentiate Alzheimer's Disease From Lewy Body Disease.
Patients with memory disorders are experiencing different trends which are difficult to predict. Moreover, the distinction between Lewy body disease and Alzheimer's disease is not easy as both diseases can present similar…
- Trial name
- AlphaLewyMa (NCT01876459)
- Testing
- MRI, lumbar puncture, neuropsychological tests
- Where
- France
- Volunteers
- 265 people
- Sponsor
- University Hospital, Strasbourg, France
Parkinsons Disease
Pilot Study Evaluating Safety of Unilateral Gamma Knife Subthalamotomy for Parkinson's Disease
This is a pilot study to evaluate the safety and efficacy of unilateral gamma knife subthalamotomy for Parkinson's disease in patients deemed poor candidates for deep brain stimulation.
- Trial name
- GKSTN (NCT02249559)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Spasmodic Dysphonia, Singer's Dystonia
Brain Networks in Dystonia
To date, there is only limited knowledge about the distinct neural abnormalities that lead to the development of different forms of focal dystonia.
- Conditions
- Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia
- Trial name
- NCT03042962
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Parkinson Disease, Kinesiophobia
The Effect of Kinesiophobia on Physical Activity, Balance and Falling in Parkinson's Disease Patients
The kinesiophobia; defined as irrational fear of movement, which may occur after painful injury and reduce physical activity. It develops the idea that movement in individuals will cause re-injury and cause additional pain to…
- Conditions
- Parkinson Disease, Kinesiophobia, Physical Activity, Balance
- Trial name
- NCT03827746
- Testing
- Tampa Kinesiophobia Scale, Berg-Balance Test, International Physical Activity Questionnaire-Short Form, Falls Efficacy Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Kültür University
Functional Neurological Disorder, Functional Movement Disorder
The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions Among Patients With Functional Neurological Movement Disorders
Functional neurological movement disorders are common conditions that can lead to significant limitations in daily life. They result from a functional disorder in the brain.
- Trial name
- NCT07588282
- Testing
- Psychoeducational communication guide for first-diagnosis of FND
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Medical University of Graz
Parkinson Disease
Transcutaneous Afferent Patterned Stimulation (TAPS) for Reduction of Parkinson's Disease (PD) Related Action Tremor
Demonstrate safety and efficacy of TAPS delivered by a Cala device as a treatment for action tremor in subjects with Parkinson's disease hand tremor
- Trial name
- NCT05012579
- Testing
- Cala Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cala Health, Inc.
Tardive Dyskinesia, Schizophrenia
Extract of Ginkgo Biloba and Tardive Dyskinesia
The purpose of this study is to determine whether Extract of Ginkgo Biloba is effective in the treatment on Tardive dyskinesia
- Trial name
- EGBTD (NCT00672373)
- Testing
- Extract of Ginkgo Biloba (EGb-761 capsules)
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Beijing HuiLongGuan Hospital
Tourette Syndrome
Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression
The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics in subjects with medically refractory debilitating Tourette Syndrome.
- Trial name
- NCT05371041
- Testing
- Medtronic Percept Neurostimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Parkinson Disease
Comparative Effects of Alexander Techniques and Feldenkrais Method in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by tremors, rigidity, and postural instability. These symptoms significantly impact balance and increase the risk of falls, which subsequently lead to a…
- Trial name
- NCT06750224
- Testing
- Alexander technique, Feldenkrais method
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Huntington's Disease
Creatine Therapy for Huntington's Disease
This study, CREST-HD, will examine the safety and tolerability of 8 grams of creatine in subjects affected by Huntington's disease (HD).
- Trial name
- NCT00026988
- Testing
- Creatine
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Parkinson Disease, Occupational Therapy
Effectiveness of Online Program and Task-related Training for Parkinson's Disease
The goal of this clinical trial is to compare the effectiveness of online self-management program and on-site task-related training for people with early stage Parkinson's disease.
- Conditions
- Parkinson Disease, Occupational Therapy, Telerehabilitation, Activities of Daily Living
- Trial name
- NCT06248073
- Testing
- on-line self-management training, onsite task-related training
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung University
Parkinson Disease
Pharmacist-led Perioperative Medicines Optimisation
Patients attend pre-assessment clinics (POAC) who require an elective operation and who are having a general anaesthetic. At POAC patients are asked about their health, and past medical conditions to assess their fitness for…
- Trial name
- NCT04228770
- Testing
- Meeting with pharmacist
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Huntington Disease
Feasibility of a Video-oculography in Patients With Huntington's Disease VOG-HD Study
The purpose of this study is to know the limits of feasibility of a reliable oculomotor record for patient with Huntington's disease.
- Trial name
- VOG-HD (NCT02563418)
- Testing
- Eye-tracking
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Parkinson's Disease
The Effect of Low Frequency STN DBS on Sleep and Vigilance in Parkinson's Disease (PD) Patients
The study design is a within-subject randomized cross-over design to evaluate the effects of DBS on sleep architecture, as measured by polysomnography, and on wake-time vigilance, as measured by a virtual reality street-crossing…
- Trial name
- NCT01769690
- Testing
- DBS stimulator setting alteration, virtual reality simulator
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease
Comparison of Different Rehabilitation Protocols in Parkinson's Disease With Postural Instability and Gait Disorders
The aim of the study is to compare the effects of 2 different dosages and modalities of motor-cognitive rehabilitation in Parkinson's disease with postural instability and gait disorders (PD-PIGD) on clinical features…
- Trial name
- NCT05799690
- Testing
- Gait and balance training with dual-task + action observation and motor imagery (six weeks), Gait and balance training with dual-task (six weeks), Gait and balance training with dual-task + action observation and motor imagery (twelve weeks: 6 + 6)
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Massimo Filippi
Parkinson Disease, Gait Disorders, Neurologic
Investigating Neural Biomarkers for Gait in Parkinson's Patients
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.
- Trial name
- NCT05820074
- Testing
- Neural Activity Recording, Movement Parameter Recording, Neuromodulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Huntington Disease
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease
WVE-HDSNP2-002 is an open-label extension (OLE) study to evaluate the safety, tolerability, PK, PD, and clinical effects of WVE-120102 in adult patients with early manifest HD who carry a targeted single nucleotide polymorphism…
- Trial name
- NCT04617860
- Testing
- WVE-120102
- Where
- 20 sites in Australia, Canada and 5 more
- Volunteers
- 36 people
- Sponsor
- Wave Life Sciences USA, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.