Clinical trials: Movement Disorder
Parkinson Disease
Social Self-Management of Parkinson's Disease
Parkinson's disease (PD) affects 1% to 2% of the US population over age 60, and its prevalence is increasing as the population ages.
- Trial name
- SocM-PD (NCT03938974)
- Where
- 2 sites in United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Tufts University
Parkinson Disease
Assessment of the Biodistribution and Safety of 123-I MZINT in Healthy Subjects and Parkinson Disease Patients
The overall plan of this project is to evaluate [123I] mZINT as a tool to assess SERT density in humans. This protocol will be completed in three parts.
- Trial name
- NCT00427674
- Testing
- [123I] mZINT injection and serial dynamic SPECT imaging
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Stroke, Rehabilitation
Virtual Reality Mirror Therapy With Focused Object-Directed Attention System
In this study, the investigators hypothesized that Virtual Reality Mirror Therapy with Focused Object-Directed Attention (VRMTFOA) would yield superior therapeutic effects compared to conventional Virtual Reality Mirror Therapy…
- Conditions
- Stroke, Rehabilitation, Virtual Reality, Mirror Movement Therapy
- Trial name
- NCT07525713
- Testing
- task-oriented training
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Parkinson Disease
Blood Biomarker in Early Parkinson's Disease
Currently, there are no cures or disease modifying therapies for Parkinson's disease (PD). This is partially due to the inability to detect the disease before it has progressed to a stage where there are clinical manifestations.
- Trial name
- NCT03384797
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Duke University
Haemophilia
Movement Visualization in Pain Management in Patients With Hemophilic Arthropathy.
Background. The recurrence of hemarthrosis in patients with hemophilia favors the development of a progressive, degenerative intra-articular lesion (hemophilic arthropathy).
- Trial name
- HeMirror (NCT04549402)
- Testing
- Mirror Therapy group, Video group
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Parkinson's Disease
Serotonin and Amyloidopathy
The purpose of this study is to determine if changes in brain serotonin affects the accumulation of amyloid in the brain. The investigators will use brain imaging methods to measure the amount of serotonin and amyloid in the…
- Trial name
- NCT02895932
- Testing
- PET imaging
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Parkinson Disease, Tremor
Action Observation Therapy and Mirror Therapy in Parkinson's Disease
Small muscles of the hand are affected due to involuntary movements and slowing of voluntary movements seen in Parkinson's disease. There is a loss of fine dexterity and coordination in the hand.
- Trial name
- NCT05350709
- Testing
- mirror therapy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cystic Fibrosis
Fidgety Movements in Cystic Fibrosis
Very low birth weight infants who are at risk for chronic lung diseases may also be at risk for brain anomalies such as increased echogenicity, leukomalacia and intracranial hemorrhage.
- Trial name
- NCT03381157
- Testing
- Observational General Movements Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Deep Brain Stimulation, PARKINSON DISEASE (Disorder)
Cortical Network Modulation by Subthalamic Nucleus DBS
Deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson's disease (PD) can provide substantial motor benefit yet can also produce unwanted mood and cognitive side effects.
- Trial name
- NCT04922411
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson Disease
Effects of Rhythmic Auditory Cueing on Stepping in Place in Patients With Parkinson's Disease
Patients with Parkinson's disease have internal rhythm dysfunction, which may affect the rhythmic movements such as walking. Poor regularity of the rhythmic movement may lead to freezing of gait.
- Trial name
- NCT03271736
- Testing
- Stepping-in-place exercise with external auditory cues, Transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- HsiuYun Chang
Essential Tremor
Acamprosate and Methazolamide for Essential Tremor
This is an investigator initiated study is designed to evaluate the anti-tremor benefits of two marketed medications, methazolamide and acamprosate in subjects with a diagnosis of essential tremor (ET).
- Trial name
- NCT06312800
- Testing
- Acamprosate, Methazolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Parkinson, Parkinson Disease
Virtual Reality and Fear of Falling in Parkinson's Disease
Background: Falls are common in elderly individuals and those with neurological conditions like Parkinson's disease. Parkinson's disease causes postural instability and mobility issues that lead to falls and reduced quality of…
- Conditions
- Parkinson, Parkinson Disease, Parkinson's Disease and Parkinsonism
- Trial name
- NCT05931692
- Testing
- Virtual reality, Electroencephalogram, Electromyography
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Parkinson's Disease
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics Profile of MT101-5 in Healthy Volunteers
The primary study objective is to establish the safety and tolerability of MT101-5 after a single and multiple dose administrations in healthy volunteers.
- Trial name
- NCT05844787
- Testing
- MT101-5
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mthera Pharma Co., Ltd.
Huntington Disease
Evaluation of Three Tests to Assess Social Cognition in Huntington Disease
The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease.
- Trial name
- NCT07253038
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Parkinson Disease
Functional Connectivity Parkinson Disease
In this study the investigators are looking at two subtypes of Parkinson Disease (PD); "tremor-dominant" (TD) and postural imbalance and gait disorder (PIGD).
- Trial name
- NCT01798563
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infertility
The Role of Extracellular pH on Spermatozoa's Directional Movement in Vitro
The purpose of this research project is to determine whether or not the directional movement of spermatozoa is influenced by a pH gradient by examining spermatozoa in vitro.
- Trial name
- NCT03574714
- Testing
- Extracellular pH
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Parkinson Disease, Amyotrophic Lateral Sclerosis (ALS)
Discovery and Validation of Protein Structural Complexes in Circulating Biofluids As Novel Biomarkers for Early Diagnosis, Prognosis and Therapeutic Management of Patients Affected by Neurodegenerative Disorders
Neurodegenerative disorders (NDDs), such as Parkinson¿s disease (PD), Alzheimer¿s disease (AD), Frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are characterized by aggregation and intracellular accumulation…
- Conditions
- Parkinson Disease, Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Alzheimer's Disease (AD)
- Trial name
- NCT06803784
- Testing
- Genetic: whole genome sequencing, whole exome sequencing
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Subacromial Impingement Syndrome
Effects of Myofascial Chain Tension Modulation Combined With Scapular Corrective Exercise on Scapular Movement Performance and Functional Outcomes in Tennis Players With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is characterized by abnormal scapular motion, including decreased upward rotation, increased internal rotation, and excessive anterior tilting, which impair shoulder and arm function.
- Trial name
- NCT07385378
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Elastic band
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Periodontal Diseases, Cancer Metastatic
Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients.
To investigate the effect of Low Level Laser therapy on orthodontic tooth movement of periodontally compromised patients by evaluating the rate of orthodontic tooth movement and the level of Osteocalcin in the gingival crevicular…
- Conditions
- Periodontal Diseases, Cancer Metastatic, Orthodontic Tooth Movement
- Trial name
- NCT05739838
- Testing
- Biolase ;Low Level Laser
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
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