Clinical trials: Movement Disorder
Respiratory Disease
Results of Manual Therapy on Pulmonary Parameters
The main objective of this study is to evaluate the effectiveness of different manual techniques included traditionally on respiratory physical therapy
- Trial name
- NCT01735474
- Testing
- Manual technique
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Spondylosis
Mulligan Mobilizations and McKenzie Exercises Along With Neural Mobilizations in Cervical Spondylosis
Cervical pain is one of the common problem among general population. However, cervical spondylosis may cause unavoidable neck pain and range limitations due to wear and tear changes in the cervical spine.
- Trial name
- NCT05768438
- Testing
- Mulligan with upper limb movement, McKenzie exercises with neural mobilizations
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Aging, Emotions
Emotion Study/Substudy: Flexible Brain Study
The proposed research applies the highly innovative technology of real-time functional Magnetic Resonance Imaging (rtfMRI) to examine plasticity of brain-regulatory mechanisms related to cognitive and affective processing and to…
- Conditions
- Aging, Emotions, Parkinson Disease
- Trial name
- NCT03872414
- Testing
- Anterior cingulate cortex activation, Primary auditory cortex activation
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson Disease, Balance
Effects of Intensity-matched Agility and Cycling Exercise Training on PD Patients' Clinical Symptoms, Posture, and Mobility
Determine the short-term and lasting effects of intensity-matched exercise programs on level 2-3 PD patients' clinical symptoms, postural control, and mobility. Hypothesis 1.
- Conditions
- Parkinson Disease, Balance, Rehabilitation, Motor Function
- Trial name
- NCT03193268
- Testing
- Single-blind RTC of PD patients, cycling
- Where
- Hungary
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Parkinson Disease
The Effect of tDCS on a Motor-cognitive Dual-task Performance of Parkinson's Patients
The concurrent performance of two tasks, i.e., dual tasking (DT), is a common and ubiquitous every day phenomena. For example, people frequently walk while talking on a cellphone or drive while talking to a passenger.
- Trial name
- NCT02503930
- Testing
- Active tDCS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Exercise and Transcranial Magnetic Stimulation: Increasing Brain Plasticity in Parkinson's Disease
This is a feasibility and exploratory study consisting of two parts: first, a cross-sectional (one-time) biomarker measurement comparing BDNF-TrkB (Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB,) signaling and…
- Trial name
- NCT02741765
- Testing
- Real rTMS, Supervised aerobic exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Parkinson Disease
The Dutch Parkinson and Cognition Study
Parkinson Disease (PD) is a heterogeneous, progressive neurodegenerative disorder which is characterized by a variety of motor and non-motor symptoms.
- Trial name
- DUPARC (NCT04180865)
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Parkinsonian Syndrome
A Study of Brain Imaging With Nuclear Medicine Technology in Individuals With and at Risk for Parkinson's Disease
This study involves study participants who have been clinically diagnosed with parkinsonian syndrome or who are at-risk for parkinsonian syndrome, have a family history of parkinsonian syndrome or exposure to environmental toxins…
- Trial name
- NCT00117819
- Testing
- [123I]ß CIT and SPECT imaging
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Healthy
Investigating the Cognitive Processes That Underlie Social Knowledge and Behavior
The purpose of the protocol is to localize the neural regions and systems mediating the forms of knowledge representations hypothesized by the principal investigator to be stored in the human prefrontal cortex.
- Trial name
- NCT00061334
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pressure Ulcer
Monitoring Movement for Pressure Ulcer Prevention
The goal of this work is to develop and test an automated movement detection monitoring tool that could lead to reduced burden on clinicians and in-turn reduce pressure ulcer incidence rates.
- Trial name
- NCT03114800
- Testing
- E-Scale
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jonathan Pearlman
Parkinson's Disease
Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA)
The study will investigate the biomarker of a-synuclein aggregate in CSF detected by protein misfolding cyclic amplification (PMCA) and its sensitivity and specificity in diagnosing Parkinson's disease at H-Y stage I and disease…
- Trial name
- NCT04536857
- Testing
- Biomarker assay
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Huashan Hospital
Parkinson's Disease, Multiple System Atrophy
PET Imaging Evaluation of [11C]SY08
The overall goal of the proposed research is to evaluate the use of [11C]SY08 as a PET radiotracer for aggregated alpha synuclein (αS) in individuals with Parkinson's disease (PD), Multiple system atrophy (MSA), Dementia with…
- Conditions
- Parkinson's Disease, Multiple System Atrophy, Dementia With Lewy Bodies, Healthy Controls
- Trial name
- NCT06098612
- Testing
- C11-SY08
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Gilles de la Tourette's Syndrome
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders…
- Trial name
- NCT00664300
- Testing
- Facial expression recognition of emotion
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Parkinson's Disease
Single Ascending Dose Study of MEDI1341 in Healthy Volunteers
This is a study of single ascending intravenous doses of MEDI1341 or placebo in up to 48 healthy volunteers, aged 18 to 65 years. The study will include up to 6 planned cohorts; each cohort will comprise 8 participants.
- Trial name
- NCT03272165
- Testing
- MEDI1341
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Memory Disturbances
Functional Magnetic Resonance Imaging Study of Jaw-tapping Movement on Memory Function
The purpose of this study is to examine the possibility of using jaw-tapping training as a self-exercise for developing memory and preventing dementia in elderly subjects with memory disturbances using functional magnetic…
- Trial name
- NCT01873664
- Testing
- Jaw-tapping
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Tourette Syndrome, Sensory Disorders
Neural Correlates of Sensory Phenomena in Tourette Syndrome
The most pervasive sensory manifestation of TS is sensory over-responsivity (SOR). SOR is defined as excessive behavioral response to commonplace environmental stimuli.
- Conditions
- Tourette Syndrome, Sensory Disorders, Hypersensitivity, Tics
- Trial name
- NCT03914664
- Testing
- Electroencephalogram (EEG) testing procedure, Autonomic function testing procedure
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Huntington's Disease
Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's Disease
The pace of basic science research defining the mechanisms of selective neuronal degeneration in Huntington disease (HD) has far exceeded the pace of translation of this information into clinically effective treatments for the…
- Trial name
- HD (NCT00670709)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dystonia, Parkinson Disease
DYSCAR: Characterization of Dystonia
Dystonia is a rare disease leading to a severe handicap. It can be of primary or secondary origin. It is characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures.
- Trial name
- NCT00361465
- Testing
- EMG and Kinematics recording
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy Participants
Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants
This Phase I, randomised, single-blind, placebo-controlled study has been designed to assess the safety, tolerability, and pharmacokinetics (PK) of AZD2693 following subcutaneous (SC) administration of AZD2693 in healthy…
- Trial name
- NCT05107336
- Testing
- AZD2693
- Where
- Japan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.