Clinical trials: Movement Disorder
Chronic Musculoskeletal Disease, Chronic Pain, Widespread
Effects of Acute Exercise on Pain and Human Movement
The aim of this research project is to evaluate the effect of an acute exercise intervention on pain intensity and movement control.
- Trial name
- eMOVE (NCT03882333)
- Testing
- Acute exercise
- Where
- Sweden
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Parkinson Disease
Multi-limb Dual-task Control in Parkinson's Disease
People with Parkinson disease commonly experience difficulty driving, which requires the arms and legs to do different tasks simultaneously.
- Trial name
- NCT03662009
- Testing
- multilimb dual task
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- A.T. Still University of Health Sciences
Parkinson Disease, MSA - Multiple System Atrophy
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease
Clinical diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) is challenging, especially in the early stages.
- Conditions
- Parkinson Disease, MSA - Multiple System Atrophy, Lewy Body Dementia (LBD), Neurodegenerative Disease
- Trial name
- EXTRAORDINARY (NCT06846658)
- Where
- 3 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Parkinson Disease(PD)
Cycling and Treadmill With Dual Task for Parkinson's Disease Improvement
Motor impairment in lower extremities is common in individuals with Parkinson disease (PD). Development sensitive test for early motor deviations is important.
- Trial name
- NCT06355947
- Testing
- Cognitive cycling training, Cognitive treadmill training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Parkinson's Disease, Disturbance; Balance, Labyrinth
Analysis of the Parameters Obtained on Stabilometric Platform in Patients With PD
Objective: To analyze different parameters in patients with Parkinson's Disease (PD) obtained through the use of a stabilometric platform and compare them with those of a control population.
- Conditions
- Parkinson's Disease, Disturbance; Balance, Labyrinth, Other Falls
- Trial name
- SPPD001 (NCT02098655)
- Testing
- Stabilometric platform
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Mesial Movement of Teeth
Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration
This study aimed to evaluate the effect of using full thickness mucoperiosteal flap (FTMPF) elevation only versus low level laser therapy (LLLT) on acceleration of orthodontic tooth movement.
- Trial name
- NCT04055935
- Testing
- elevation of full thickness mucoperiosteal flap, low level laser therapy
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Parkinson Disease
PK Study of WD-1603 in Healthy Subjects
An open label, balanced, randomised, four-treatment, four-period, four-sequence, single oral dose, crossover Pharmacokinetics study of WD-1603 carbidopa/levodopa extended-release tablets in normal, healthy, adult human subjects…
- Trial name
- NCT04591535
- Testing
- WD-1603 CARBIDOPA/LEVODOPA EXTENDED-RELEASE TABLETS
- Where
- India
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hong Kong WD Pharmaceutical Co., Limited
Parkinson Disease
Counterfactual Thinking and Decision-making in Parkinson's Disease
The aim of this research is to verify the ability of counterfactual thinking about medical decisions in individuals affected by Parkinson's Disease when compared to healthy individuals.
- Trial name
- CT_PD (NCT05756543)
- Testing
- Counterfactual Inference Test
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Parkinson Disease, Sexual Orientation
Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+
Study Rationale: Older adults who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have worse health than non-LGBTQ+ older adults.
- Trial name
- LGBTQ+_PD (NCT05502055)
- Testing
- Individual interviews, Focus Groups, National Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Creighton University
Parkinson Disease
Parkinson's Disease and Gamma-transcranial Alternating Current Stimulation
Cortical-basal ganglia gamma oscillations are pathologically reduced in Parkinson's disease (PD) and the plasticity of the primary motor cortex (M1) is impaired.
- Trial name
- NCT06297538
- Testing
- gamma transcranial alternating current stimulation (tACS)
- Where
- Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Parkinson Disease
Initial Investigation of [18F]P17-059 in Parkinson's Disease Patients and Healthy Volunteers
This study investigates the initial safety profile of [18F]P17-059 in healthy volunteers including dosimetry determination, and compares regional brain uptake and kinetics of [18F]P17-059 in Parkinson's disease patients with…
- Trial name
- NCT03903549
- Testing
- [18F]P17-059
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Five Eleven Pharma, Inc.
Gilles de la Tourette Syndrome, Tourette Syndrome
Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI
Gilles de la Tourette syndrome (GTS; also known as Tourette syndrome) is a congenital neuropsychiatric disorder. Characteristic symptoms are so-called tics-rapid, repetitive movements (motor tics) or vocalizations (vocal tics)…
- Trial name
- NCT05232955
- Testing
- PET/MR scanner
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Multiple Sclerosis, CVA
Feasability, Validty and Reliability of Inertial Sensors
This study has 3 aimes: 1. To investigate the feasibility of using IMUs (Xsens, MVN Studio) during functional tasks to assess upper limb kinematics in pwMS and stroke survivors.
- Trial name
- NCT03668990
- Testing
- IMUs (Xsens, MVN Studio)
- Where
- 2 sites in Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Multiple System Atrophy
High-Altitude Neurodegeneration Cohort (HANC) Study
Chronic physiological hypoxia has been implicated in the pathogenesis of multiple system atrophy (MSA), a fatal neurodegenerative disorder of unknown etiology.
- Trial name
- HANC (NCT07657520)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- West China Hospital
Parkinson's Disease, Essential Tremor
Movement Disorder Quantification Algorithm Development
The purpose of this study is to collect kinematic motion data from subjects with movement disorders such as Parkinson's disease (PD) and essential tremor (ET) to develop and validate algorithms for quantifying motor symptoms such…
- Trial name
- NCT01534650
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Alzheimer Disease, Dementia With Lewy Bodies (DLB)
Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This is a retrospective observational study to evaluate the clinical utility of blood-based biomarkers in the diagnosis and management of patients with a neurodegenerative disease (ND) or mental disorder (MD).
- Conditions
- Alzheimer Disease, Dementia With Lewy Bodies (DLB), Frontotemporal Dementia (FTD), Major Depressive Disorder (MDD)
- Trial name
- Synapsing-BK (NCT07314190)
- Where
- Spain
- Volunteers
- 1,799 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Parkinson Disease
Role of Nasal Dysbiosis in Parkinson Disease
Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such…
- Trial name
- SMELLPARK (NCT04249245)
- Testing
- Nasal Swab
- Where
- 2 sites in France, Guadeloupe
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Parkinson Disease
DAT SPECT and Procedural Motor Skills in Parkinson's Disease
Patients with Parkinson's disease (PD) are known to be affected by subtle cognitive impairment early in the disease course, mostly in the executive field.
- Trial name
- NCT03076307
- Testing
- Procedural Motor Skills with mirror-drawing of figures
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Essential Tremor
Ventrointermediate Nucleus (VIM DBS) and Working Memory
This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET)…
- Trial name
- WMVIM (NCT00906412)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Movement, Involuntary
Mental Practice on Balance
The main objective of this research is to see the effect of two mental practice techniques on static and dynamic balance.
- Trial name
- NCT04548336
- Testing
- Motor Imagery, Action observation
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
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