Clinical trials: Movement Disorders, Functional
Parkinson Disease
Investigation of Validity and Reliability of the Minnesota Manual Dexterity Test in Parkinson's Disease
Parkinson's Disease (PD) is a disease that affects upper extremity functional skills with clinical findings such as bradykinesia, rigidity, and hypokinesia, and causes limitations in patients' daily life activities.
- Trial name
- NCT06713707
- Testing
- Manuel dexterity, Manual Dexterity (only MMDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Schizophrenia, Psychosis
Effects of Music Beat on Motor Function in Individuals At Risk for Psychotic Onset and Schizophrenia Patients
The purpose of this project is to investigate whether a 3-week training program involving music beat (serving as a type of rhythmic auditory stimulation) reduces the severity of bradykinesia and dyskinesia in at-risk individuals…
- Conditions
- Schizophrenia, Psychosis, Parkinsonism, Dyskinesias
- Trial name
- NCT04929795
- Testing
- Rhythmic auditory stimulation (RAS), no RAS
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Dr WANG Shumei
Parkinson Disease
LRRK2 Mutation and Parkinson's Disease
The Leucine-Rich Repeat Kinase 2 (LRRK2) is implicated in autosomal dominant Parkinson's disease (PKD). An inhibitor for the leucine-rich repeat kinase 2 (LRRK2) is in pre-clinical development for potential use in treating…
- Trial name
- NCT01424475
- Testing
- Healthy, PKD Patients
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Brain Damage, Cerebral Palsy
Efficacy of Modified Constraint-induced Movement Therapy in Children With Brain Damage
This research centers on the comparison of the immediate efficacy (right after therapy) and the maintained efficacy (3 months and 6 months) between "Modified Constraint-Induced Movement Therapy" (mCIMT) group and control group at…
- Conditions
- Brain Damage, Cerebral Palsy, Traumatic Brain Damage
- Trial name
- NCT01076257
- Testing
- Modified Constraint-induced Movement Therapy
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease, Autonomic Dysfunction
Parkinson's Autonomic Responses to Treadmill Walking
This study will compare examine autonomic and cardiovascular responses to peak exercise testing in Parkinson's disease patients in varying stages of the disease, and healthy, age-matched participants.
- Trial name
- NCT03156400
- Testing
- Exercise Stress Test
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Parkinson Disease
Changes in Functional Performance in Individuals With Parkinson's Disease Following 2-month Physiotherapy Intervention
Aim of current study was to evaluate the effect of a 2-month comprehensive physiotherapy intervention on different aspects of functional performance.
- Trial name
- NCT03568903
- Testing
- Comprehensive physical therapy
- Volunteers
- 44 people
- Sponsor
- University of Tartu
Essential Tremor
Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy
Focused ultrasound for Essential Tremor is an FDA approved treatment performed by neurosurgeons at the Ohio State Center for Neuromodulation that utilizes ultrasound technology to create a lesion in the thalamus of Essential…
- Trial name
- NCT03560622
- Testing
- multi-modality neuroimaging
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vibhor Krishna
Cauda Equina Syndrome, Functional Neurological Disorder
BLB Study Back or Leg Pain and Bladder Symptoms Study
The research focuses on Cauda Equina Syndrome (CES) which describes damage to the nerves in the lower back which supply bladder, bowels, sexual function and the legs usually from slipped discs in the spine.
- Trial name
- BLB (NCT03325374)
- Testing
- Questionnaires and examination
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Movement Disorders
Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures
This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder.
- Trial name
- NCT00500994
- Testing
- MRI
- Where
- 2 sites in United States
- Volunteers
- 254 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Hemiplegia
The Effect of Modified Constraint Induced Movement Therapy on Upper Extremity Function in Stroke Rehabilitation
The purpose of the study is to determine the effect of Modified Constraint-Induced Movement Therapy and trunk restraint contrasted with conventional physical therapy treatment on improving upper extremity function, balance, and…
- Conditions
- Stroke, Hemiplegia, Chronic Stroke Patients
- Trial name
- mCIMT (NCT06692569)
- Testing
- Conventional Physical Therapy, Modified Constraint Induced Movement Therapy
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- University of Jazan
Huntington Disease
FuRST 2.0 Cognitive Pre-testing - Round 2
The study is a single, cross-sectional cognitive interview of FuRST 2.0, functional rating scale, administered to forty Huntington's Disease Gene Expansion Carriers (HDGECs) and potentially, their companions (the companion's…
- Trial name
- NCT03709173
- Testing
- FuRST 2.0
- Where
- 4 sites in United States, Canada
- Volunteers
- 52 people
- Sponsor
- CHDI Foundation, Inc.
Knee Osteoarthritis
Mixed Methods Assessment of Exercises for Knee OA
Osteoarthritis (OA) is a condition that causes cartilage loss, bony remodeling, joint stiffness and generalized muscle weakness. 90% of OA presentation has been reported within the leg; with 44% affecting the knee joint.
- Trial name
- NCT02734342
- Testing
- exercise
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Salford
Parkinson Disease, Tremor, Essential
Effectiveness and Reliability of Hypnosis in Stereotaxy
In certain neurosurgical procedures, the use of a stereotaxic frame is required. It is then possible to set a precise target (depending of the type of the surgery) to be reached by the surgeon.
- Conditions
- Parkinson Disease, Tremor, Essential, Dystonia, Primary
- Trial name
- ERST (NCT03074422)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University Hospital, Geneva
Exercise Movement Techniques, Shoulder Pain
Overhead Perturbation Training for Glenohumeral Joint Instability
The purpose of the trial is investigate the benefits of a novel, newly invented exercise technique protocol relative to physiological changes in upper limb proprioception (primary) and subjective readiness for return to sport…
- Conditions
- Exercise Movement Techniques, Shoulder Pain, Glenohumeral Subluxation
- Trial name
- OPT (NCT03380494)
- Testing
- Overhead perturbation training, Non-perturbed training
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stroke, Impaired Upper Extremity Function
Extension of the MIME Robotic System for Stroke Rehabilitation
The goal of this project is to develop and test a new robotic system to accommodate practice of tasks requiring reach, grasp and release of objects.
- Trial name
- NCT00995774
- Testing
- robotic therapy, conventional functional training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- US Department of Veterans Affairs
Neuromuscular Diseases
Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function
The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different…
- Trial name
- NCT06439823
- Testing
- ActiMyo®/Syde®
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laurent Servais
Parkinson Disease
Comparison of Sensory Cuing Modalities for Freezing of Gait
The investigators intend to compare the effects on the resolution of visual and auditory sensory cues on the resolution of freezing of gait in patients with idiopathic Parkinson's disease.
- Trial name
- NCT05080413
- Testing
- Laser shoes, Metronome
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Veterans Health Service Medical Center, Seoul, Korea
Parkinson Disease
Automated Deep Brain Stimulation Programming Using Functional Mapping
Participants will undergo DBS programming guided by the DBS-Expert system and by a clinician per standard care.
- Trial name
- DBS-Expert (NCT02765282)
- Testing
- Algorithm based programming using Kinesia-based assessment
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Parkinson Disease
Effect of a Boxing Program on People With Parkinson Disease
This study is investigating the impact of a boxing training program on people with Parkinson Disease. The investigators were provided data for the intervention group retrospectively by the organizers of the boxing club to assess…
- Trial name
- NCT04781842
- Testing
- Boxing exercise program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Husson University
Stroke
Assessment of the Stroke Rehabilitation Assessment of Movement as a Clinical Tool
The Stroke Rehabilitation Assessment of Movement (STREAM) is a relatively new measurement tool, which measures specific movement deficits (impairments) caused by a stroke.
- Trial name
- NCT00635661
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- State University of New York - Upstate Medical University