Clinical trials: Movement Disorders, Functional
Parkinson Disease
Diaphragmatic Exercise on Parkinson Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world, considering the central nervous system disorders that affect movement.
- Trial name
- NCT04108520
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Parkinson's Disease, Deep Brain Stimulation
The Effect of Electrode Implantation for Deep Brain Stimulation (DBS) on Brain Function Using Single Photon Emission Computed Tomography (SPECT) With Technetium-99m-ethyl Cysteinatedimer (Tc-ECD)
The goal of this study is to explore the effect of subthalamic nucleus (STN)-DBS surgery and stimulation in PD (Parkinson's disease) patients on regional cerebral blood (CBF) flow during cognitive task performance or at rest.
- Trial name
- NCT01037686
- Testing
- Injection of 15mCi of Tc-ECD and scanning by SPECT camera, Semantic verbal fluency task performance, Turning off the stimulator
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Conversion Disorder
Neuroimaging Biomarkers of Prognosis in Motor Functional Neurological Disorders
Functional Neurological Disorder (FND/ Conversion Disorder) is a highly prevalent and disabling neuropsychiatric condition. Motor FND symptoms include Nonepileptic Seizures, Functional Movement Disorders and Functional Weakness.
- Trial name
- NCT03398070
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
COPD, Chronic Musculoskeletal Pain
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi…
- Trial name
- WATCH for Pain (NCT05701982)
- Testing
- Every Step Counts-Tai Chi, Usual Care
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Functional Neurological Disorder, Convulsion, Non-Epileptic
Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND
The purpose of this study is to help providers develop an interdisciplinary treatment pathway for functional neurological disorder (FND) at University of Alabama at Birmingham (UAB), and will involve psychiatry, speech therapy…
- Conditions
- Functional Neurological Disorder, Convulsion, Non-Epileptic, Functional Seizure
- Trial name
- NCT06362161
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease (PD)
Idiopathic Parkinson's Disease: Interest of an Early Group-Based Cognitive Rehabilitation Program (LIFECOG-PD)
Current pharmacological treatments have not demonstrated significant improvement in cognitive impairment in Parkinson's disease (PD).
- Trial name
- LIFECOG-PD (NCT07813156)
- Testing
- cognitive rehabilitation program
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Parkinson Disease
Cell Studies of Parkinson's Disease
This study will examine and compare blood samples from healthy volunteers and patients with Parkinson's disease to identify abnormalities associated with Parkinson's disease.
- Trial name
- NCT00076505
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Idiopathic Parkinson Disease
Effects of Sensory-Motor Integration Training in Patients with Idiopathic Parkinson's Disease
The goal of this single blind randomized controlled trial is to investigate the effect of sensory-motor integration training on cognitive functions, balance and gait in patients with Parkinson Disease? The main questions it aims…
- Trial name
- NCT06390163
- Testing
- Sensory-Motor Integration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
ADHD - Attention Deficit Disorder With Hyperactivity
Evaluation of the Relationship Between Medication, Eye Movements, and Autonomic Nervous System (ANS) Functions in Children and Adolescents With ADHD
An increasing number of children are being diagnosed with ADHD, and the demand for ADHD medication has been rising. Although ADHD medication is often effective, this is unfortunately not the case for all children and adolescents…
- Trial name
- POP-Eye/ANSA (NCT07634809)
- Testing
- metylphenidate
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Umeå University
Tourette Syndrome in Adolescence, Social Adjustment
Board Game Project for Adolescents with Tourette Syndrome
The study aims to investigate the effectiveness of using a board game to improve adolescents' tics, mental health, and interpersonal interactions.
- Conditions
- Tourette Syndrome in Adolescence, Social Adjustment, Psychosocial Functioning
- Trial name
- NCT05566236
- Testing
- board game
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Parkinson Disease
Pilot Study to Determine if Working Memory Training Aids Cognitive Functioning in Patients With Parkinson's Disease
This project will investigate the feasibility and preliminary effectiveness of an intensive and focused working memory training program for patients in the early stages of PD receiving dopaminergic therapy.
- Trial name
- PDWM (NCT01647698)
- Testing
- Adaptive working memory training task, Non-adaptive working memory training task (i.e. an active control task), No training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Gail Eskes
PARKINSON DISEASE (Disorder)
Effects of Tai Chi Therapy Versus Qi-Gong in Stage-I Parkinson's Patients.
This study has important clinical, academic, and practical relevance in neuromuscular rehabilitation. Clinically, it aims to identify effective and tolerable rehabilitation strategies for individuals with Parkinson's disease by…
- Trial name
- NCT07662837
- Testing
- Tai Chi, Qi Gong
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Parkinson's Disease and Parkinsonism
Diaphragmatic Thickness and Pulmonary Function in Parkinson's Disease
Ultrasound can give important information about the morphology of the diaphragm and the amount of contraction. Our aim, with the prediction that a restrictive pathology will occur in the pulmonary function with the addition of…
- Trial name
- NCT05194748
- Testing
- No intervention, observational only
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Abant Izzet Baysal University
Functional Movement Disorders
Brain Activity in People With Functional Movement Disorders
This study will use functional MRI (fMRI, a technique that shows what areas of the brain are active when performing different mental tasks), to examine how the brain in people with functional movement disorders (FMD) may differ…
- Trial name
- NCT00448084
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hemorrhagic Stroke, Ischemic Stroke
Effects of Short-intensity Modified Constraint-induced Movement Therapy on Hand Function in Stroke Patients.
To determine effects of short-intensity modified constraint-induced movement therapy on hand function in stroke patients.
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Rehabilitation
- Trial name
- NCT05916885
- Testing
- short-intensity modified CIMT and conventional therapy, conventional therapy alone
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Secondary Dystonia
Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia
The disability inflected by dystonia encouraged the development of many neurosurgical procedures. This is a prospective study included 120 patients suffering from intractable secondary dystonia.
- Trial name
- NCT03347240
- Testing
- Brain Lesioning, Combined anterior and posterior lumbosacral rhizotomy, Deep brain stimulation
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Parkinson Disease, Parkinson Disease 10
Effects of Different Physical Therapies and Dance in People With Parkinson's Disease
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare with unsupervised home exercises in the…
- Trial name
- NCT03860649
- Testing
- Nordic Walking, Jogging, Dance
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Rio Grande do Sul
Parkinson Disease
Emotion, Mood and Executive Function in Parkinson's Disease (PD)
The current study aims to assess the effect of an 8 week Azilect treatment (as adjunct therapy to levodopa) on affect perception and emotional expressiveness in a double-blind placebo-controlled study.
- Trial name
- RasQ (NCT01385735)
- Testing
- Rasagiline
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- St. Josef Hospital Bochum
Spinal Cord Injury
Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia
In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after…
- Trial name
- NCT05157282
- Testing
- TESS, Training, Motor Task
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Functional Movement Disorder
Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Background: Functional movement disorders (FMD) involve involuntary movements that are not due to a recognized neurological or medical cause. FMD can cause major disability.
- Trial name
- NCT05155059
- Testing
- MagStim
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institutes of Health Clinical Center (CC)