Clinical trials: Movement Disorders, Functional
Parkinson's Disease and Parkinsonism, Glymphatic System
Effects of Exercise on Glymphatic Functioning and Neurobehavioral Correlates in Parkinson's Disease
This study is designed to measure the change in patients diagnosed with Parkinson's disease (PD) before, during and after a 12 week exercise program.The focus of this study is the glymphatic system.
- Trial name
- FIGHTPD (NCT04140708)
- Testing
- Exercise--Rock Steady Boxing class
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Vanderbilt University Medical Center
Parkinson Disease (PD)
Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease.
- Trial name
- NCT07536542
- Testing
- Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ankara University
Functional Movement Disorder, Functional Neurological Disorder
Tremor Retrainer Software Application for Functional Tremor
The purpose of this clinical trial is to learn about the Tremor Retrainer smartphone application and Simplified Functional Movement Disorder Rating Scale in patients with functional tremor.
- Conditions
- Functional Movement Disorder, Functional Neurological Disorder, Functional Neurological Symptom Disorder
- Trial name
- NCT06257069
- Testing
- Tremor Retrainer Smartphone Application
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Functional Neurological Symptom Disorder
Measuring Change in Individuals With Functional Neurological Symptom Disorder
Functional Neurological Symptom Disorders (FNSD) are one of the commonest reasons why patients are referred to neurologists. They are as disabling as neurological disorders causing similar symptoms related to more readily…
- Trial name
- NCT07864454
- Testing
- STH Specialist Neurology Pyschotherapy
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hepatocellular Carcinoma
Watch and Wait and Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) accounts for more than 90% of primary liver cancers and is the sixth most common cancer in the world and ranked third in mortality.
- Trial name
- WATCH (NCT05349331)
- Testing
- Liver Resection
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sun Yat-sen University
Parkinson Disease
Role of Deep Brain Stimulation on Social Cognition in Parkinsonian Patients
Parkinson's disease (PD) is usually responsible of cognitive and behavioral non-motor signs with a major impact on the quality of life.
- Trial name
- NCT03004573
- Testing
- Neuropsychological detailed tests with focus on social cognition
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Hospices Civils de Lyon
Parkinson's Disease, Freezing of Gait
Effect of Virtual Reality on Freezing Phenomenon, Balance, Functional Mobility, Participation in Parkinson's Patients
This study was planned to investigate the use and results of virtual reality applications with specially prepared software for the rehabilitation of freezing phenomenon, which increases the falling anxiety of individuals with…
- Trial name
- NCT06390553
- Testing
- Task-Oriented Virtual Reality Application with Crowd Simulation, Conventional Parkinson Rehabilitation
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara Yildirim Beyazıt University
Parkinson Disease (PD)
L-THEANINE AND MEDITERRANEAN DIET ON RBD, GI FUNCTION, AND INFLAMMATION IN PARKINSON'S DISEASE
Parkinson's disease is a progressive neurological disorder associated with severe dopaminergic neuron loss in the substantia nigra pars compacta.
- Trial name
- NCT07682532
- Testing
- Dietary Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Medipol University
Parkinson's Disease, Mild Cognitive Impairment
Effect of Transcranial Magnetic Stimulation on Cognition and Neural Changes in Parkinson's Disease
Parkinson's disease (PD) affects more than 100,000 Canadians and results in symptoms affecting both motor and cognitive (thinking and memory) functions.
- Trial name
- PD-MCI-TMS (NCT03243214)
- Testing
- TMS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of Calgary
Parkinson's Disease
Development of a Face Valid Executive Functioning Task
The purpose of this study is to develop a task to measure executive thinking skills that can be performed in a laboratory setting, but has clear parallels to the thinking demands of real life situations, and can be administered…
- Trial name
- MedTask (NCT00918112)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson Disease
Speed Manipulated Adaptive Rehabilitation Therapy Bike for Parkinson's Disease
Parkinson's disease (PD) is a progressive neurological disorder that results in slowness of movement, muscle stiffness, tremor, and postural instability.
- Trial name
- SMART (NCT05361200)
- Testing
- Dynamic high-cadence cycling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kent State University
Stroke, Rehabilitation
Augmented-reality Based Mirror Therapy in Stroke Rehabilitation
In the proposed study, the investigators assumed that mirror therapy combined with augmented reality technology will provide a better treatment effects than traditional mirror therapy for the patients with unilateral stroke.
- Conditions
- Stroke, Rehabilitation, Technology, Mirror Movement Therapy
- Trial name
- NCT05580744
- Testing
- Traditional occupational therapy, Mirror therapy using a mirror box, Augmented reality-based mirror therapy
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Parkinson Disease
Progression in Cognitive ADLs in Parkinson's Disease
Mild cognitive impairment (PD-MCI) is one of the greatest risk factors for future Parkinson's disease dementia (PDD). A recent meta-analysis found that, on average, 31% of patients with PD-MCI converted to PDD within seven years…
- Trial name
- PRICOG-PD (NCT05806866)
- Testing
- Cognition scores, cognitive instrumental activities of daily living scores
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University Hospital Tuebingen
Urinary Bladder Sphincter Disorder
Study of Bladder-sphincter Symptoms in Functional Neurological Disorders
A significant proportion of patients with functional neurological disorders (FND) report urinary, anorectal or genitosexual disorders. However, until now, no study has focused on bladder-sphincter disorders in patients with FND.
- Trial name
- URO-TNF (NCT05689866)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease
PC in Stance and During Functional Mobility Following BIG for PD
LSVT BIG is an intensive, amplitude based rehabilitation program that has been demonstrated to improve one of the hallmark features of Parkinson's disease, specifically bradykinesia.
- Trial name
- NCT04877951
- Testing
- LSVT BIG
- Volunteers
- 5 people
- Sponsor
- University of South Dakota
Parkinson's Disease
Attentional Performance in Parkinson Disease
Background: Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain.
- Trial name
- NCT04428931
- Where
- United States
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
PARKINSON DISEASE (Disorder), Parkinsonism or Parkinson's Disease Nos
Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease
Parkinson´s disease and parkinsonian syndromes are associated with progressive motor and non-motor impairments that may compromise functional independence and quality of life.
- Trial name
- SARCOPARKINSON (NCT07907302)
- Testing
- Nutricional Education and General Exercise Guidelines, Progressive Resistance Training With Cognitive Dual-Task Training, Progressive Resistance Training With Cognitive Dual-Task and Inestability Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Valencia
Parkinson's Disease, Physical Activity
Effect of High Intensity Interval Training on Mechanisms of Neuroplasticity in Parkinson's Disease Patients
There are experimental evidences of the important role of high intensity physical exercise in Parkinson's disease (PD) treatment, that induces similar effects to pharmacotherapy.
- Conditions
- Parkinson's Disease, Physical Activity, Neurorehabilitation, Neuroplasticity
- Trial name
- NCT04204551
- Testing
- high-intensity interval training (HIIT), conventional physical therapy
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Stroke, Upper Extremity Paresis
Virtual Reality Based Mirror Therapy
The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.
- Conditions
- Stroke, Upper Extremity Paresis, Upper Extremity Paralysis
- Trial name
- NCT06152328
- Testing
- Virtual reality applications based on mirror therapy, Conventional treatment, Mirror therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Abant Izzet Baysal University
Joint Loose Bodies
Different Methods of Physical Therapy for Stroke
It is estimated that worldwide, about 15 million people are affected by vascular accident (CVA) per year, and in Brazil, the stroke is a major cause of death and disability, generating too much economic and social impact by…
- Trial name
- NCT02932631
- Testing
- THERAPY CONTROL AND MOVEMENT OF INDUCTION
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba