Clinical trials: Movement Disorders, Functional
Parkinson Disease
Subthalamic Nucleus Connectivity in Parkinson's Disease With Ultra-high Field Magnetic Resonance Imaging
The purpose of this study is to investigate the segregation of the subthalamic nucleus into its motor and non-motor regions in patients with Parkinson's disease and healthy controls with the aid of ultra-high field magnetic…
- Trial name
- NCT01981577
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Parkinson Disease
Effects of Kinesthetic Stimuli During XBOX Kinect Training on People With Parkinson's Disease
A single-blind, parallel-group, randomised trial will be conducted in Sao Paulo, Brazil. People with Parkinson's Disease (PD) will be recruited at "Brazil Parkinson Association" (BPA), a non-governmental association of PD care…
- Trial name
- NCT04717271
- Testing
- Movement Guidance Group, No Movement Guidance Group
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Functional Neurological Disorder
Pilot Neurobehavioral Therapy for Functional Neurological Disorder
The goal of this pilot randomized clinical trial is to learn if Neurobehavioral Therapy (NBT) works to treat motor functional neurological disorder (mFND) (also referred to as functional motor disorder).
- Trial name
- NBT for mFND (NCT06873698)
- Testing
- Neuro-behavioral Therapy, Standard Medical Care (SMC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rhode Island Hospital
Parkinson Disease
Robotic Assessments of Hand Function in Patients With Parkinson's Disease
It has been shown that patients with Parkinson's disease (PD) have impaired kinaesthesia and haptic perception of the upper limbs.
- Trial name
- RHK Parkinson (NCT05245955)
- Testing
- Assessments of the hand sensory function with the ReHapticKnob
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Parkinson´s Disease, Acetylcholine
Quantification of Cerebral Cholinergic Function in Parkinson´s Disease by Means of Nuclear Medicine Methods
Parkinson´s disease is based on a Lewy body degeneration of cerebral and extracerebral neurons. This Lewy body degeneration includes cerebral cholinergic neurons besides dopaminergic neurons.
- Conditions
- Parkinson´s Disease, Acetylcholine, SPECT
- Trial name
- NCT01003535
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Universität des Saarlandes
Movement Disorders
Treatment of Functional Movement Disorders With Psychotherapy
Background: Functional movement disorder (FMD) is a form of conversion disorder (CD). CD is a disorder in which a person has neurological symptoms that do not have a neurological cause.
- Trial name
- NCT01778517
- Testing
- Group Psychotherapy, Cognitive behavior therapy based on self help
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease, Executive Dysfunction
Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.
- Trial name
- NCT03285347
- Testing
- Computer-based cognitive training
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Parkinsons Disease (PD), Oropharyngeal Dysphagia
Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder and frequently leads to oropharyngeal dysphagia, a swallowing disorder that strongly affects patient health and quality of life.
- Trial name
- NCT07299448
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Functional Movement Disorder
Study of the Ability of a New Technique to Effectively Diagnose Movement Disorders
Sante Fe is an investigation of a new technique to distinguish between different types of movement disorders, specifically organic versus functional, by observing changes in involuntary movements in two different situations.
- Trial name
- Sante-Fe (NCT03661021)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Parkinson Disease
A Prospective Longitudinal Assessment of PD Functional Impairment and Disability Via Mobile Health Technology
The purpose of this study is to compare data from a battery of novel mobile health technologies to standard-of-care validated patient questionnaires and clinician rating scales in Parkinson's disease patients.
- Trial name
- NCT05153356
- Testing
- Personal Kinetigraph, Kinesia 360
- Sponsor
- Rush University Medical Center
Movement Disorders
rTMS Effect in Functional Psychogenic Movement Disorders Applied Alone Then Combined With Hypnotherapy
The management of functional psychogenic movement disorders (FNPMD) is challenging for neurologists and psychiatrists and only comprehensive multidisciplinary treatment programme can be worthwhile for these patients (Moene et al…
- Trial name
- MOVHYSTIM (NCT02471066)
- Testing
- rTMS
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
Rectal Cancer
Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)
Primary hypothesis: Side-to-end anastomosis is non-inferior to colon J pouch for reconstruction after low anterior resection for rectal cancer in fecal incontinence (Wexner score).
- Trial name
- SAVE (NCT01006577)
- Testing
- side-to-end anastomosis, colon j pouch
- Where
- Germany
- Volunteers
- 306 people
- Sponsor
- Charite University, Berlin, Germany
PD - Parkinson's Disease
Effects of Propofol on Brain Function in Patients With Parkinson's Disease
Propofol is a short-acting general anesthetic drug commonly used in clinical practice, with rapid clinical onset of action, amnesic, anxiolytic, antiepileptic, and muscle relaxant effects.
- Trial name
- NCT05895019
- Testing
- Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Tiantan Hospital
Parkinson's Disease, Balance
Whole-Body Vibration in Parkinson Disease
The aim of this study is to evaluate the effects of different frequencies of Whole Body Vibration (WBV) application on balance, gait, cognitive functions, and dual-task performance in patients with Parkinson's disease.
- Conditions
- Parkinson's Disease, Balance, Gait, Cognitive Function
- Trial name
- NCT07678983
- Testing
- Functional Exercise Based Physiotherapy, Low-Frequency Whole-Body Vibration Therapy, Medium-Frequency Whole-Body Vibration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Izmir Bakircay University
Heart; Disease, Mitral(Valve)
Rapid and Easy Evaluation of Cardiac Systolic Function by Means of Mitral Valve Movements in the Emergency Department
Left ventricular ejection fraction (LVEF) is a parameter that should be evaluated rapidly to the patients, admitted to the emergency department with shortness of breath.
- Trial name
- NCT02657824
- Testing
- dyspneic patients
- Volunteers
- 113 people
- Sponsor
- Bozyaka Training and Research Hospital
Neurodegenerative Diseases, Alzheimer Disease
[18F]MC225-PET in Neurodegenerative Disease
P-glycoprotein, an efflux transporter at the blood-brain barrier plays an important role in de development of neurodegenerative disease.
- Conditions
- Neurodegenerative Diseases, Alzheimer Disease, Parkinson Disease, Mild Cognitive Impairment
- Trial name
- NCT05853471
- Testing
- [18F]MC225
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Parkinson's Disease
Psychiatric and Cognitive Manifestations of Parkinson's Disease
Parkinson's Disease (PD) is often thought of as affecting movement only. In fact, most patients also experience psychiatric and cognitive symptoms, sometimes from the disease itself, and sometimes as a side-effect of PD…
- Trial name
- NCT00360633
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Functionnal Neurological Disorder
Exploring Transdiagnostic Psychological Processes in Functional Neurological Disorder
Functional neurological disorder (FND) is a little-known borderline disorder between psychiatry and neurology, which is benefiting from renewed research.
- Trial name
- Process-TNF (NCT06691295)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Stroke
FES VS Constrained Induced MT Recovery and Spasticity in Upper Limb Hemiparetic Ischemic Patients
To determines the effects of Functional Electrical Stimulation versus Constrained Induced Movement Therapy for motor recovery and spasticity in Upper Limb Hemiparetic Chronic Ischemic Stroke Patients
- Trial name
- NCT05854121
- Testing
- Functional Electrical Stimulation, Constrained Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Superior University
Huntington Disease
PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD
This study will evaluate the efficacy and safety of pridopidine 45mg twice daily (BID) in patients with early stage manifest Huntington Disease (HD).
- Trial name
- NCT04556656
- Testing
- Pridopidine
- Where
- 58 sites in United States, Austria and 9 more
- Volunteers
- 499 people
- Sponsor
- Prilenia