Clinical trials: Movement Disorders, Functional
Breast Cancer
Mindful Movement for Breast Cancer Survivors
The purpose of this study is to determine if participating in a Mindful Movement Program (MMP) (learning how to be mindful in one's movement), positively affects the body's immune functions improves mindfulness and reduces…
- Trial name
- NCT02619292
- Testing
- Mindful Movement Program
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Saint John's Cancer Institute
Stroke
Comparative Effects of Intensive and Distributed CIMT on Upper Extremity Function in Stroke Patients
The main question this clinical trial is aims to answer is whether intensive and distributed constraint-induced movement therapy has similar effects on upper extremity function in participants with stroke.
- Trial name
- NCT06459336
- Testing
- Intensive constraint-induced movement therapy, Distributed constraint-induced movement therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Parkinson's Disease, Mild Cognitive Impairment
rTMS to Improve Cognition in Parkinson's
The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical…
- Trial name
- TMSCogReP (NCT03836950)
- Testing
- MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Parkinson Disease
Mapping Levodopa Effects on Cortico-basal Ganglia Circuit Function in Parkinson's Disease
Levodopa-induced dyskinesia (LID) in Parkinson's disease (PD) are involuntary movements caused by long-term treatment with dopaminergic replacement therapy (levodopa). During the cause of PD, most patients develop LID.
- Trial name
- Dyn-fMRI-PD (NCT06240624)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Patellofemoral Pain
Bilateral Knee Pain and Dry Needling
This project will evaluate the effects of bilateral knee pain and dry needling (DN) on laterality recognition, movement and muscle function.
- Trial name
- NCT05976269
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Parkinson Disease
Dance in Parkinson's Disease. A Greek Pilot Study
Dance for Parkinson's Disease® (DfPD®) is a structured dance program that has never been evaluated in Greek PD population. This study assesses for the first time the efficacy, safety and feasibility of DfPD® program in Greek PD…
- Trial name
- NCT05134506
- Testing
- Dance for PD® classes
- Where
- Greece
- Volunteers
- 16 people
- Sponsor
- University of West Attica
Stroke, Rehabilitation
Changes in and Determinants of Movement Performance, Functional Status, and Health-Related Quality of Life After Stroke Rehabilitation
A total of 144 stroke patients 6 -24 months post onset who are between 45 and 75 years old will be recruited. A randomized-blocks pretest and posttest control group design will be applied.
- Trial name
- NCT00780533
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Parkinson's Disease, REM Sleep Behavior Disorder
Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder
Up to 60% of Parkinson's Disease (PD) patients suffer from REM sleep behavior disorder (RBD), a parasomnia. This disorder is thought to be related to a dysfunction of limbic system and brainstem.
- Trial name
- MP-TCSP-IRMf (NCT02824341)
- Testing
- fMRI
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Thoracic Outlet Syndrome
Mobilization With Movement on Pain, Function, and Quality of Life in Patients With Thoracic Outlet Syndrome
This study will investigate whether adding Mobilization With Movement (MWM) to a standardized rehabilitation program improves arm, shoulder, and hand function in adults with chronic neurogenic thoracic outlet syndrome (nTOS)…
- Trial name
- NCT05917756
- Testing
- Mobilization with Movement (MWM), Standardized Rehabilitation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ahram Canadian University
Sports Physical Therapy, Physical Functional Performance
Outdoor Horseback Riding and Its Effects on Muscle Strength, Balance, Sleep, and Movement
This study aims to investigate the effects of regular outdoor horseback riding on lower extremity muscle strength, core stabilization, balance, functional movement capacity, sleep quality, and overall well-being in healthy…
- Conditions
- Sports Physical Therapy, Physical Functional Performance, Horseback Riding
- Trial name
- NCT07286864
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istinye University
Parkinson Disease
Impact of Exercise in Parkinson's Disease
The goal of this research is to identify an intervention that will improve cognition and sleep in persons with PD.
- Trial name
- NCT03495193
- Testing
- Exercise training, Sleep hygiene
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Parkinson's Disease
The Effect of Low-frequency rTMS on Motor Function in PD Patients With Freezing of Gait
This study is a double blind comparative study examining the effectiveness of the rTMS treatment on Freezing of Gait (FOG) phenomenon in patients with Parkinson's disease.
- Trial name
- NCT02221544
- Testing
- Low-frequency repetitive Transcranial Magnetic Stimulation, rTMS maintenance
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson's Disease
Apomorphine Effect on Nociceptive Perception in Parkinson's: a Clinical and Imaging Study
Patients suffering from Parkinson's disease (PD) frequently experienced painful sensations. We suppose that painful symptoms could be related to the neurotransmitter deficit of PD.
- Trial name
- APODOUL (NCT00524914)
- Testing
- apomorphine
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Toulouse
Globus
Treatment in Patients With Globus: Psychoeducation, Anxiolytics or Proton Pump Inhibitors
A randomized controlled trial study is conducted to compare treatment efficacy between psycho-education, anxiolytics drug and proton pump inhibitors in participants who met the criteria of globus.
- Trial name
- NCT03205228
- Testing
- Omeprazole, psychoeducation, Flupentixol +Melitracen
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Diabetes Complications, Peripheral Arterial Disease
Collaborative-care Rehabilitation After Dysvascular Amputation
The objective of this study is to examine the feasibility of using a collaborative-care, home-based rehabilitation program to improve functional outcomes for people recovering from lower limb amputation caused by vascular…
- Trial name
- NCT01929018
- Testing
- Exercise, Walking Program, Health Self-Management Support
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Parkinson Disease, Parkinson Disease 10
Effects of Nordic Walking in Parkinson Disease Patients
The aim of this study was to evaluate and compare the effects of a Nordic and free walking training program on clinical, functional and biomechanical parameters of gait, in people with PD.
- Trial name
- Walking (NCT03355521)
- Testing
- Nordic Walking, Free Walking
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of Rio Grande do Sul
Parkinson's Disease
Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients
The objective of this protocol is to investigate the microstructural alterations and monoaminergic function in Parkinson's disease patients with impulse control disorders and cognitive impairment by multimodal MRI and 18F-DTBZ…
- Trial name
- NCT02599753
- Testing
- 18-FDTBZ
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson's Disease
A Study in Healthy Male Volunteers to Investigate a New Drug for the Treatment of Parkinson's Disease
The main purpose of the study is to identify the best dose of V81444 to use in future trials in patients with Parkinson's disease.
- Trial name
- NCT02764892
- Testing
- V81444
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Vernalis (R&D) Ltd
Functional Neurological Disorder
Behavioural and Electrophysiological Effects of rTMS in Functional Neurological Disorders
The purpose of this study is to better understand Functional Neurological Disorders (FND) by measuring movement timing and brain activity in patients with FND during deliberate movements and when expressing an 'intention' to…
- Trial name
- NCT04942600
- Testing
- MagStim Rapid2 Transcranial Magnetic Simulation
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Manitoba
Parkinson Disease
Mapping Functional Networks of Brain Activity (Brain Network Activation, BNA) Based on Analysis of Evoked Response Potential (ERP) Signals for Healthy Controls Evoked Response Potential (ERP) Signals for Healthy Controls and Patients With Parkinson Disease
A cornerstone in PD research is the investigation of neurophysiological changes as potential biomarkers that could help in tracking disease progression and response to therapies.
- Trial name
- NCT02149498
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Oren Cohen