Clinical trials: Movement Disorders, Functional
Functional Movement Disorder, Parkinson Disease
Movement Disorders and Early Maladaptive Schemas
Functional neurological disorders (FND) are neurological symptoms that cannot be explained by a lesion or related to an identified dysfunction of the central nervous system.
- Conditions
- Functional Movement Disorder, Parkinson Disease, Dystonic Disorders
- Trial name
- SCHEMAF (NCT03717376)
- Testing
- Self-questionnaire YSQ-S3 (Young Schema Questionnaire)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries, Spinal Cord Diseases
Non-invasive Spinal Cord Stimulation After Spinal Cord Injury
Spinal cord injury (SCI) is a central nervous system injury that often leads to motor dysfunction. Non-invasive electrical stimulation of the spinal cord has been recognized as a potential method of reactivating lost spinal…
- Trial name
- SCI-ES-WALK (NCT06260735)
- Testing
- Trans-spinal electrical stimulation, Electrical muscle activation, Treadmill walking
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Parkinson's Disease
Exercise Study For People With Parkinson's Disease
This study is designed to compare three different exercise approaches to learn which program is best for people with early and mid-stage Parkinson's disease.
- Trial name
- NCT00387218
- Testing
- Exercise, Physical therapy
- Where
- 4 sites in United States
- Volunteers
- 170 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Parkinson Disease
Cognitive-Motor Training for Gait Adaptability in Parkinson Disease
Cognitive-motor training combines thinking tasks with physical movements, encouraging participants to choose appropriate actions and adjust their movements according to different task demands.
- Trial name
- NCT07907718
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Parkinson Disease
Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)
In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking.
- Trial name
- NCT00993291
- Testing
- Frequency change to 60 Hz, Frequency change to 130 Hz
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University
Cerebrovascular Accident
Neural Mechanisms and Efficacy of Dual Neurotechnology-aided Mirror Therapy in Chronic Stroke: Neural and Motor Plasticity, Movement Performance, Daily Function, and Quality of Life
Mirror therapy (MT) has been demonstrated, in terms of neuroplasticity, to improve sensorimotor function of paretic upper extremity (UE) in chronic stroke patients.
- Trial name
- NCT04326205
- Testing
- transcranial direct current stimulation, tDCS, functional electrical stimulation, FES, no stimulation
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease
Effect of Physical Rehabilitation in Patients With Parkinson's Disease
This is a prospective study. The aim of this study is to investigate the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with…
- Trial name
- NCT06021834
- Testing
- rehabilitation
- Volunteers
- 40 people
- Sponsor
- Faculty of Medicine, Sousse
Parkinson's Disease
Functional Characterization of Parkin + Patients
Parkinson's disease is one of the most frequent neurodegenerative diseases, and for which the mechanisms remains unknown. Since the implication of susceptibility factors is highly suspect, we have recently shown that one…
- Trial name
- NCT00142311
- Where
- 14 sites in France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Spinal Cord Injury
Grasping Function After Spinal Cord Injury
The overall goals of this proposal are to examine the contribution of physiological pathways to the control of grasping behaviors after cervical SCI, and to maximize the recovery of grasping by using tailored non-invasive brain…
- Trial name
- NCT03447509
- Testing
- iTMS, Motor Task, Training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dementia With Lewy Bodies, Alzheimer Disease
Optical Neuroimaging and Cognition
Dementia is associated with a variety of neurovascular and neurometabolic abnormalities. Traditional imaging techniques used to investigate such abnormalities, such as Positron Emission Tomography and functional Magnetic…
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- ONAC (NCT05460143)
- Testing
- Near-infrared Spectroscopy scan, Magnetic Resonance Imaging scan
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Parkinson Disease
Novel Paradigms of Deep Brain Stimulation for Movement Disorders
Investigators will enroll patients who are already selected to undergo deep brain stimulation surgery based on standard of care.
- Trial name
- NCT04563143
- Testing
- Novel DBS Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Parkinson's Disease
Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease
The primary purpose of this study is to compare the effects of a non-traditional boxing training program to a traditional therapeutic exercise program on activity and participation outcomes in persons with Parkinson's disease.
- Trial name
- NCT01014663
- Testing
- Traditional Therapeutic Exercise, Non-Contact Boxing Training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Indianapolis
Spasmodic Dysphonia, Focal Dystonia
Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia
This study will examine how the brain controls speech in patients with spasmodic dysphonia, a voice disorder that involves involuntary spasms of muscles in the larynx (voice box), causing breaks in speech.
- Trial name
- NCT00713414
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease, Exercise
Effectiveness of Video-Based Upper Extremity Exercise Program in Parkinson's Disease
Over the past decade, virtual reality (VR) has been widely recognized as a therapeutic tool that enables neurological patients to interact with simulated environments through multiple sensory channels.
- Conditions
- Parkinson Disease, Exercise, Exergame, Therapy
- Trial name
- NCT06807411
- Testing
- Conventional exercise, Video game based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
PARKINSON DISEASE (Disorder)
Effect of Hand Rehabilitation on Cognitive Function in Patients With PD
Evidence suggests the association between fine motor skills of the hand and cognitive function, as well as the positive effects of hand rehabilitation on hand function and the effectiveness of cognitive rehabilitation on…
- Trial name
- NCT07702929
- Testing
- Hand Sensorimotor Rehabilitation, Cognitive Remediation
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Isfahan University of Medical Sciences
Parkinson's Disease
The Effects of Dual Task Training in Individuals With Parkinson's Disease
The primary aim of the proposed project is to characterize dual tasking (DT) deficits to improve motor, cognitive, and quality of life outcomes in individuals with Parkinson's disease (PD).
- Trial name
- NCT02538029
- Testing
- Dual Task Group, Single Task Group
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Nonhemorrhagic Ischemic Stroke, Motor Function
Observational Study to Evaluate the Simplified-STroke REhabilitation Assessment of Movement (S-STREAM) Scale in Subjects Who Have Experienced a Nonhemorrhagic Ischemic Stroke
The purpose of this study is to evaluate the utility of the S-STREAM as an instrument to assess motor function in subjects who have experienced a nonhemorrhagic ischemic stroke.
- Trial name
- NCT01496885
- Testing
- Observational study
- Where
- 27 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- Daiichi Sankyo
Cerebral Palsy, Developmental Coordination Disorder
Bootle Blast: Understanding the Family Experience
One in 60 children have a physical disability that can impact activities and participation. Occupational and physical therapies can be of great benefit, but are costly and difficult to access.
- Conditions
- Cerebral Palsy, Developmental Coordination Disorder, Developmental Disability, Autism Spectrum Disorder
- Trial name
- NCT06161168
- Testing
- Bootle Blast Play Phase (B)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Stroke
Assessment of Eye Movements in Stroke Patients and Closed-loop Intervention
The current study evaluates first the assumption that eye-movements during free viewing behavior are potential biomarkers of visuospatial deficits in stroke population.
- Trial name
- EMS (NCT06965673)
- Testing
- Visual exploration training, Standard neuropsychological rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy