Clinical trials: Movement Disorders, Functional
Postoperative Ileus
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery The research will be carried out as a randomized controlled experimental study in patients with open…
- Trial name
- NCT04466319
- Testing
- Rocking Chair
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Eskisehir Osmangazi University
Stroke, Osteopathic Medicine
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
Stroke remains the leading cause of severe disability, and survivors frequently have incomplete recovery. More than half of older survivors have impaired mobility which contributes to poorer quality-of-life (QoL) and suffering.
- Conditions
- Stroke, Osteopathic Medicine, Physical Examination, Heart Rate Variability (HRV)
- Trial name
- SOMADC-CC (NCT07737873)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Cerebral Palsy
Feasibility of Vision-Language Models for Detecting Physical Assistance as an Observable Criterion Defining GMFCS Levels in Children Aged 2 to 6 Years With Cerebral Palsy
The GMFCS sorts children with cerebral palsy into five levels of gross motor function. What mainly separates one level from the next is two things an observer can see: whether another person has to physically help the child move…
- Trial name
- NCT07824531
- Testing
- Vision-language model assessment of movement video
- Where
- 2 sites in South Korea
- Volunteers
- 26 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson's Disease
Cognitive impairment is a common non-motor symptom among individuals living with Parkinson's disease (PD). Traditionally, cognitive impairment is thought to reflect disruptions in dopaminergic frontal-striatal systems.
- Trial name
- NCT05419453
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- California State University, San Bernardino
Parkinson Disease, Motor Cortex
Effects of rTMS on Balance Performance and Functional Mobility in Parkinson's Disease
This study aimed to investigate the effects of rTMS on balance performance and functional mobility in people with PD. Additionally, it further examines the effects of single-session low-frequency and high-frequency repetitive…
- Conditions
- Parkinson Disease, Motor Cortex, Excitability, Balance
- Trial name
- NCT07195773
- Testing
- rTMS
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chung Shan Medical University
Functional Neurological Disorder, Functional Movement Disorder
The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions Among Patients With Functional Neurological Movement Disorders
Functional neurological movement disorders are common conditions that can lead to significant limitations in daily life. They result from a functional disorder in the brain.
- Trial name
- NCT07588282
- Testing
- Psychoeducational communication guide for first-diagnosis of FND
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Medical University of Graz
Elderly
Relationship of Balance, Functional Capacity and Fear of Movement With Lower Extremity Muscle Strength in Elderly
Aging is a period in which the morphological, physiological and pathological changes progress negatively, accompanied by various diseases and regression of physical and mental abilities.
- Trial name
- NCT04347356
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bezmialem Vakif University
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder
Virtual Reality-Augmented Constraint-Induced Movement Therapy Versus Conventional Constraint-Induced Therapy for Upper Limb Rehabilitation in Children With Unilateral Cerebral Palsy.
Cerebral palsy (CP) causes persistent motor and postural impairments that can limit children's functional independence and participation.
- Conditions
- Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder, Upper Limb Functions, Virtual Reality Based Therapy
- Trial name
- NCT07853937
- Testing
- Rehabilitation intervention
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Faculty of Medicine, Sousse
Essential Tremor, Parkinson Disease
RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease
To determine the efficacy of frameless Virtual Cone Radiosurgical Thalamotomy for medically refractory tremor resulting from either Essential Tremor or Tremor-Dominant Parkinson's Disease with the Fahn-Tolosa-Marin Tremor Rating…
- Trial name
- NCT03305588
- Testing
- Unframed Virtual Cone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Essential Tremor, Tremor
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor (ET) is the most common tremor disorder, currently affecting an estimated 2.9 million Americans and leading to disability and decreased quality of life in 75% of cases.
- Trial name
- NCT02495883
- Testing
- Ethanol, Propranolol
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Stroke
Kinesiotaping and Constraint Induced Movement Therapy in Subacute Stroke
In stroke patients, the most common neurological deficits were motor impairment, loss of somatosensation, abnormal muscle tone, and impaired fractionated movement at affected limbs.
- Trial name
- NCT03682666
- Testing
- Kinesiotaping, modified Constraint Induced Movement Training
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Functional Movement Disorder
Digital Telerehabilitation in Functional Motor Disorders
Functional motor disorders (FMDs) are a broad spectrum of functional neurological disorders, including abnormal gait/balance disorders.
- Trial name
- NCT06274281
- Testing
- Digital Telerehabilitation, Usual care
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Parkinson Disease
SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease
The purpose of this study is to examine the safety and efficacy of postural training emphasized on the integration of multiple sensory information into motor control in individuals with PD.
- Trial name
- SegwayPD (NCT05982730)
- Testing
- Sensory-Augmented Postural Training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson Disease (PD)
Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs
Parkinson's disease (PD) is a progressive neurological condition that can affect movement, balance, endurance, and overall quality of life.
- Trial name
- NCT07221266
- Testing
- Guided Cycling, Non-Contact Boxing, Traditional Physical Therapy Program (Standard of Care)
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Texas, El Paso
Parkinsons Disease (PD)
Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and fatigability in PD patients.
- Trial name
- tDCS (NCT06883266)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Sanford Health
Functional Neurological Symptom Disorder
Trial Of Neurostimulation Treatment and Investigation for Causes of Functional Motor Symptoms: a Pilot Study
A pilot randomised controlled trial (RCT) of single-pulse transcranial magnetic stimulation (TMS) over the motor cortex to investigate efficacy in improving motor FND symptoms and to make a preliminary investigation of predictors…
- Trial name
- TONICS (NCT05829005)
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- King's College London
Parkinson Disease
Spinal Cord Stimulation for Parkinson's Disease Rehabilitation
This study explores the use of multifunctional, non-invasive spinal cord transcutaneous stimulation (scTS) to address axial motor symptoms, particularly gait dysfunction, in Parkinson's disease (PD).
- Trial name
- NCT06804642
- Testing
- Spinal cord transcutaneous stimulation (scTS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Parkinson Disease, Physical Activity
Neuroplasticity in Parkinson´s Disease After Training
This project aims to determine the effects of the HiBalance program on neuroplastic changes in people with mild to moderate Parkinson´s disease.
- Conditions
- Parkinson Disease, Physical Activity, Gait Disorders, Neurologic, Neural Degeneration
- Trial name
- BETA-PD (NCT03213873)
- Testing
- HiBalance, Speech and communication therapy
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Karolinska Institutet
Writer's Cramp
Sensorimotor Mapping in Patients With Writer's Cramp
Writer's cramp (WC) is a form of focal dystonia, a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both.
- Trial name
- IWCToxin (NCT03085745)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble