Clinical trials: Mucositis, open to volunteers
Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer
Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy.
- Conditions
- Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer, Head &Amp; Neck Squamous Cell Carcinoma
- Trial name
- RICE-MUC (NCT07242859)
- Testing
- rice bran
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Christina Milad Lobos
Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer
Sancai Fengsui Decoction for RTOM: A Multicenter RCT
How to promote the prognosis and outcome of RTOM, restore oral function, and improve quality of life are key issues for improving the long-term outcomes of head and neck malignant tumor radiotherapy, and are also integral parts…
- Conditions
- Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer, Oral Mucositis of RTOG Grade Greater Than 1
- Trial name
- NCT07692997
- Testing
- Sancai Fengsui Decoction
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Peri-implant Mucositis
Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis
This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters.
- Trial name
- NCT06305000
- Testing
- Non-surgical treatment, Free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Oral Mucositis (Ulcerative) Due to Radiation, Nasopharyngeal Carcinoma (NPC)
Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma
This clinical trial aims to understand whether taurine can prevent and reduce severe radiation-induced oral mucositis in patients with nasopharyngeal carcinoma undergoing radiotherapy.
- Trial name
- NCT07567742
- Testing
- Taurine
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Sun Yat-sen University
Nasopharyngeal Cancinoma (NPC), Radiation-induced Oral Mucositis
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
To explore the efficacy of Houyanqing Oral Liquid combined with conventional treatment in preventing and treating radiation-induced oral mucositis, so as to improve the quality of life of nasopharyngeal carcinoma patients…
- Trial name
- NCT07311772
- Testing
- Houyanqing Oral Liquid, Conventional Treatment for Radiation-Induced Oral Mucositis
- Where
- 16 sites in China
- Volunteers
- 386 people
- Sponsor
- Sun Yat-sen University
Peri-implant Health, Free Gingival Graft
Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implant Mucosa
This study aims to evaluate the effects of autogenous grafts harvested from different palatal regions on the peri-implant mucosa when applied during second-stage dental implant surgery.
- Conditions
- Peri-implant Health, Free Gingival Graft, Peri-implant Mucositis
- Trial name
- NCT07330609
- Testing
- Coronal palatal tissue, Apical palatal tissue
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Oral Mucositis, Quality of Life
Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
Head and Neck cancer patients receiving radiation therapy (with or without chemotherapy) suffer several oral complications, such as oral mucositis, which impairs quality of life of patients during radiotherapy and in the…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- NCT07739771
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Mucosa Innovations, S.L.
Peri-implant Mucositis, Peri-Implantitis
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to…
- Trial name
- NCT06063876
- Testing
- Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Oral Mucositis
A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment
The goal of this study is to describe the effect of photobiomodulation (PBM) on the incidence and severity of oral mucositis in post-operative oral cancer patients receiving radiotherapy +/- chemotherapy.
- Trial name
- PBM (NCT07387978)
- Testing
- photobiomodulation
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Radiation Mucositis, Staphylococcal Aureus Infection
Staph Nasal Decolonization to Improve Function and Feeding
Radiation therapy is a type of treatment that involves using radiation beams targeted at a cancer to destroy the cancer cells or slow their growth.
- Conditions
- Radiation Mucositis, Staphylococcal Aureus Infection, Head and Neck Cancer
- Trial name
- SNIFF (NCT07524894)
- Testing
- Mupirocin Ointment [Treatment]
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- David Palma
Oral Mucositis, Chemotherapy Effect
Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy
This study was planned as a randomized controlled experimental study in order to compare the effects of oral care with saline and black mulberry syrup in addition to sodium bicarbonate on oral mucositis level in children aged…
- Trial name
- NCT06525402
- Testing
- Sodium Bicarbonate Group (Usual care), Saline Group, Black Mulberry Syrup Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Vaginitis, Radiotherapy Induced Mucositis
Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream
The objective of this clinical trial is to understand whether triethanolamine cream can prevent and treat acute radiation vaginitis. It will also learn about the safety of triethanolamine cream.
- Trial name
- NCT07492654
- Testing
- Trolamine (Biafine)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Radiotherapy-Induced Oral Mucositis, Stomatitis
Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM)
This is a multicenter, randomized, controlled, prospective clinical trial designed to observe and evaluate the safety and efficacy of Modified Dahuang Huanglian Xiexin Mouthwash for the prevention of radiotherapy-induced oral…
- Conditions
- Radiotherapy-Induced Oral Mucositis, Stomatitis, Oral Mucositis, Radiotherapy Side Effects
- Trial name
- NCT07543978
- Testing
- Modified Dahuang Huanglian Xiexin Mouthwash
- Volunteers
- 156 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Peri Implantitis, Peri Implant Mucositis
Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid
Despite technological advances that have significantly improved dental implant osseointegration and survival rates, biological complications such as peri-implantitis and peri-implant mucositis are common around the implant.
- Trial name
- NCT07280754
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Atherosclerosis, Endothelial Dysfunction
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis…
- Conditions
- Atherosclerosis, Endothelial Dysfunction, Peri-Implantitis, Peri-implant Mucositis
- Trial name
- NCT05906810
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Catania
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Radiation-induced Oral Mucositis, Oral Malignancy
A Phase II Prospective, Open-Label, Randomized, Multicenter Study of Kangfu Spray for the Prevention of Radiation-Induced Oral Mucositis in Patients With Oral Malignancies Receiving Intensity-Modulated Radiotherapy
This is a prospective, open-label, randomized, controlled, multicenter phase II study evaluating the efficacy and safety of Kangfu Spray for the prevention of radiation-induced oral mucositis in patients with histologically…
- Trial name
- NCT07538934
- Testing
- Kangfu Spray, Standard Oral Care
- Volunteers
- 140 people
- Sponsor
- YE ZHANG
Peri-implant Mucositis
AI-Assisted Colorimetric Diagnosis of Peri-Implant Mucosal Erythema
1. Background and Rationale The visual diagnosis of peri-implant mucosal erythema (redness), a key sign of inflammation, is highly subjective and varies significantly among clinicians, leading to inconsistencies in early…
- Trial name
- NCT07349095
- Testing
- AIa assisted diagnosis
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Peri-Implant Mucositis
Short Versus Standard Dental Implants: Clinical and Biomarker Outcomes
This study compares two types of dental implants, short implants (6 millimeters or less in length) and standard implants (longer than 8 millimeters), to evaluate their effect on the health of the gum and bone tissue surrounding…
- Trial name
- NCT07828067
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inonu University
Mucositis Oral
Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young Adults
To assess the efficacy of preventive Low-Level Laser Therapy (LLLT) for reducing the incidence of WHO's grade 3-4 oral mucositis in children and young adults receiving chemotherapy regimens associated with a high rate of…
- Trial name
- MUCILA (NCT03983369)
- Testing
- Low-Level Laser Therapy
- Where
- 5 sites in France
- Volunteers
- 315 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris