Clinical trials: Multicystic Renal Dysplasia, Bilateral
Ureteropelvic Junction Obstruction
Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty
This prospective study, Randomized Trial of Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty will consist of four steps: 1.) Enrolling subjects in the study and signing the consent form…
- Trial name
- NCT02713633
- Testing
- internal Double-J stents, External Stent
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Rajeev Chaudhry
Multicystic Dysplastic Kidney, Polycystic Kidney Disease
Amnioinfusion for Fetal Renal Failure
The goal of this clinical trial is to learn if serial amnioinfusions can improve the chances of survival for fetuses with severe kidney problems that cause low amniotic fluid (anhydramnios).
- Conditions
- Multicystic Dysplastic Kidney, Polycystic Kidney Disease, Fetal Renal Anomaly, Anhydramnios
- Trial name
- NCT06728228
- Testing
- Amnioinfusion
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Fetal Care Center, PLLC
Pelviureteric Junction Obstruction, Pyeloplasty
Dismembered Pyeloplasty With and Without After Coming Stent
to compare outcome of pyeloplasty in pediatric population less than 6 months in age using an after coming stent versus stentless pyeloplasty.
- Conditions
- Pelviureteric Junction Obstruction, Pyeloplasty, Neonatal Hydronephrosis, Obstructive Uropathy
- Trial name
- NCT02138877
- Testing
- After coming stent after dismembered pyeloplasty, Stentless dismembered pyeloplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction, Ureteropelvic Junction; Obstruction, Congenital
Decision Aid for Parents of Infants With UPJO
Ureteropelvic junction obstruction (UPJO) is the most common etiology of high-grade hydronephrosis, affecting approximately 4,000-10,000 infants annually in the U.S.
- Trial name
- NCT05900375
- Testing
- Parent Decision Aid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Pelvi-ureteric Junction Obstruction
Different Surgical Modalities in the Management of Pelvi-ureteric Junction Obstruction
The study compared open pyeloplasty (OP) and laparoscopic pyeloplasty (LP) for treating Pelvi-ureteric Junction Obstruction (PUJO) in 40 patients.
- Trial name
- NCT06822270
- Testing
- open surgery, Laparoscopic Pyeloplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pediatric Urology, Ureteropelvic Junction Obstruction
Pediatric Robotic Versus Open Pyeloplasty
The objective is conduct a pilot randomized controlled trial comparing robotic and open techniques for surgical correction of congenital UPJ obstruction (pyeloplasty) in pediatric patients.
- Trial name
- NCT04884945
- Testing
- Open Pyeloplasty (OP), Robotic-Assisted Laparoscopic Pyeloplasty (RALP)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Ureteropelvic Junction Obstruction
The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of hydronephrosis in pediatric ureteropelvic junction obstruction (UPJO) patients.
- Trial name
- NCT01711996
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yonsei University
Disorder of Urinary Stent, Ureteral Spasm
Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal
This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent.
- Conditions
- Disorder of Urinary Stent, Ureteral Spasm, Ureteropelvic Junction Obstruction, Urolithiasis
- Trial name
- NCT02140970
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Colorado, Denver
Ureteropelvic Junction Obstruction
CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome
Cortical transit time on diuretic renogram as an early marker of significant obstruction in antenatally detected uretero-pelvic junction syndrome
- Trial name
- JUMP (NCT02812212)
- Testing
- ultrasonography, diuretic renography
- Where
- 5 sites in France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Ureteropelvic Junction Obstruction
Long-term Outcome of Retroperitoneoscopic One-trocar-assisted Pyeloplasty: A Single-center and Single-surgeon Experience
Open surgical dismembered pyeloplasty has traditionally been the preferred method for treating ureteropelvic junction obstruction (UPJO), with a success rate exceeding 94%.
- Trial name
- NCT06349161
- Testing
- One-trocar-assisted pyeloplasty
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- National Children's Hospital, Vietnam
Nurse-Patient Relations
A Controlled Study of Improved Javelin Side Recumbent Position and Conventional Postural Placement
The Da Vinci surgical robot Xi system assisted laparoscopic pyeloureteroplasty uses the improved javelin side lying position, which can alleviate the unsafe factors of falling from the bed caused by the conventional posture…
- Trial name
- NCT05551442
- Testing
- To explore the comparative study of different positioning methods in robot assisted laparoscopic pyeloplasty., To discuss the comparative study of different position placement methods of renal pelvis ureteroplasty on the Da Vinci robotic Xi platform
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guiyang Maternal and Child Health Care Hospital
Hematuria, Nephrolithiasis
Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors
Upper Urinary Tract Tumors have an incidence of 1 to 2 cases for 100 000 persons per year. The standard treatment for these tumors is the ablation of the kidney, ureter and a part of the bladder surrounding the ureteral orifice.
- Conditions
- Hematuria, Nephrolithiasis, Cancer of Urinary Tract, Ureteropelvic Junction Obstruction
- Trial name
- UROVISIO (NCT02276924)
- Testing
- Laser confocal microscopy
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Lille Catholic University
Hypospadias, Undescended Testis
Visual Guidelines and Tutoring in Pediatric Urological Surgery
The aim of this study is checking impact of visual guidelines (picture book) and tutoring in pediatric urologic surgery
- Conditions
- Hypospadias, Undescended Testis, Hydrocele, Ureteropelvic Junction Stenosis
- Trial name
- NCT02040389
- Testing
- Picture book, Standard preoperative education
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shaare Zedek Medical Center
Obstruction of Pelviureteric Junction
The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine
The investigators propose a prospective blinded randomized control trial (RCT) to assess the efficacy and safety of a simple method of continuous infusion of a local anesthetic, ropivacaine, via a surgical wound to control pain…
- Trial name
- NCT00930046
- Testing
- Ropivacaine wound catheter, Saline wound catheter
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Ureteropelvic Junction Obstruction, Chronic Kidney Diseases
The PRO-FUTURE Project
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls.
- Trial name
- PRO-FUTURE (NCT06382233)
- Testing
- Identification of Diagnostic Biomarkers
- Where
- 5 sites in Italy
- Volunteers
- 85 people
- Sponsor
- University of Campania Luigi Vanvitelli
Open, Laparoscopic
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
- Conditions
- Open, Laparoscopic, Dismembered Pyeloplasty, Primary Pelvi-Ureteric Junction
- Trial name
- NCT06572371
- Testing
- Laparoscopic pyeloplasty, Open pyeloplasty
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Pelvi-Ureteric Obstruction
Barbed Versus PGA Sutures in Minimally Invasive Dismembered Pyeloplasty
The main goals of this trial is to study the feasibility and safety of using barbed sutures compared to the conventional PGA (Polyglactin) sutures in minimally invasive dismembered pyeloplasty.
- Trial name
- NCT06526559
- Testing
- Barbed suture, PGA suture
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction, Renal Functional Recovery
Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO
Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children.
- Trial name
- UPJO-SWE (NCT07624019)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Beni-Suef University
Anhydramnios, Potter Syndrome
Renal Anhydramnios Fetal Therapy
Early pregnancy renal anhydramnios (EPRA) is a condition where a pregnant woman does not have any amniotic fluid around her fetus because of a problem with the fetus's kidneys.
- Conditions
- Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney
- Trial name
- RAFT (NCT03101891)
- Testing
- Serial amnioinfusions with isotonic fluid, Spinal needle, Isotonic fluid
- Where
- 9 sites in United States
- Volunteers
- 55 people
- Sponsor
- Johns Hopkins University