Clinical trials: Multifocal Motor Neuropathy
Multifocal Motor Neuropathy
A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
The purpose of this Phase 2 study is to evaluate the safety, tolerability, pharmacometrics, and efficacy of Claseprubart (DNTH103) in participants with multifocal motor neuropathy (MMN).
- Trial name
- MOMENTUM (NCT06537999)
- Testing
- Claseprubart
- Where
- 41 sites in United States, Canada and 13 more
- Volunteers
- 46 people
- Sponsor
- Dianthus Therapeutics
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), Multifocal Motor Neuropathy (MMN)
A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN)
The main aim of the study is to check for side effects from TAK-771, and to check how well TAK-771 controls symptoms in Japanese participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal…
- Trial name
- NCT05084053
- Testing
- TAK-771
- Where
- 23 sites in Japan
- Volunteers
- 26 people
- Sponsor
- Takeda
Multifocal Motor Neuropathy
Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Multifocal Motor Neuropathy.
Patients diagnosed with Multifocal Motor Neuropathy were confirmed based on the European Federation of Neurological Societies/ Peripheral. Nerve Society Guideline.
- Trial name
- NCT01827072
- Testing
- NPB-01
- Where
- Japan
- Volunteers
- 13 people
- Sponsor
- Nihon Pharmaceutical Co., Ltd
Multifocal Motor Neuropathy
A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy
This is a phase 2, randomized, double-blinded, placebo-controlled, parallel-group, multicenter trial to evaluate the safety and efficacy of 2 dose regimens of ARGX-117 versus placebo, in participants with MMN previously…
- Trial name
- ARDA (NCT05225675)
- Testing
- ARGX-117
- Where
- 40 sites in United States, Austria and 9 more
- Volunteers
- 54 people
- Sponsor
- argenx
Multifocal Motor Neuropathy (MMN)
A Study to Assess the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults With Multifocal Motor Neuropathy
The main purpose of the study is to evaluate empasiprubart use in adults living with Multifocal Motor Neuropathy (MMN). The researchers will evaluate the effect of empasiprubart on the thickness of the nerves, muscle strength…
- Trial name
- EmpaSound (NCT07610564)
- Testing
- Empasiprubart IV
- Where
- 4 sites in Georgia
- Volunteers
- 60 people
- Sponsor
- argenx
Multifocal Motor Neuropathy (MMN)
A Study of Purified Human Antibodies Administered Subcutaneously to Patients With Multifocal Motor Neuropathy (MMN)
The objective of this study is to assess efficacy, safety, and convenience of purified human antibodies administered under the skin in the treatment of MMN patients.
- Trial name
- NCT00701662
- Testing
- Vivaglobin
- Where
- 3 sites in Italy, Switzerland and 1 more
- Volunteers
- 8 people
- Sponsor
- CSL Behring
Multifocal Motor Neuropathy (MMN), MMN
A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy
The main purpose of this study is to compare empasiprubart and IVIg in adult patients with MMN. The study consists of a double-blinded part A (empasiprubart, IVIg) and an open-label part B (empasiprubart).
- Trial name
- Empassion (NCT06742190)
- Testing
- Empasiprubart, IVIG (Intravenous Immunoglobulin)
- Where
- 109 sites in United States, Australia and 24 more
- Volunteers
- 154 people
- Sponsor
- argenx
Multifocal Motor Neuropathy (MMN)
A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy
This trial is an extension of the antecedent trial ARGX-117-2002. It is a multicenter trial that has been designed to evaluate the long-term safety and tolerability, efficacy, immunogenicity, Pharmacokinetics (PK), and…
- Trial name
- ARDA+ (NCT05405361)
- Testing
- ARGX-117
- Where
- 27 sites in United States, Austria and 9 more
- Volunteers
- 51 people
- Sponsor
- argenx
Multifocal Motor Neuropathy
A Prospective Longitudinal Study in Adults With Multifocal Motor Neuropathy
This prospective longitudinal study will follow participants with Multifocal Motor Neuropathy over time and collect data on their clinical outcomes, quality of life, and use of health care resources.
- Trial name
- iMMersioN (NCT05988073)
- Where
- 114 sites in United States, Australia and 18 more
- Volunteers
- 413 people
- Sponsor
- argenx
Multifocal Motor Neuropathy
Study of the Effectiveness of Intravenous Immune Globulin (10%) for the Treatment of Multifocal Motor Neuropathy
The purpose of the study is to evaluate the efficacy (effect on grip strength and disability) and safety/tolerability of IGIV, 10% in subjects with Multifocal Motor Neuropathy.
- Trial name
- NCT00666263
- Testing
- Immune Globulin Intravenous (human), 10%
- Where
- 17 sites in United States, Canada and 1 more
- Volunteers
- 50 people
- Sponsor
- Baxalta now part of Shire
Motor Neuron Disease
LIME Study (LFB IVIg MMN Efficacy Study)
The aim of this study is to evaluate the efficacy and safety of I10E (LFB 10% ready-to-use liquid human intravenous immunoglobulin) compared to Kiovig® for the maintenance treatment of MMN in a randomized, double-blind, active…
- Trial name
- LIME (NCT01951924)
- Testing
- Biological : I10E (Human normal Immunoglobulin for intravenous administration 100mg/mL), Biological: Kiovig® (Human normal Immunoglobulin for intravenous administration 100mg/mL)
- Where
- 18 sites in France, Italy and 2 more
- Volunteers
- 23 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies