Clinical trials: Multimodal Analgesia
Morbid Obesity
Effect of Oxalidine Combined with Reduced-opioid Anesthesia on Multimodal Analgesia in Morbidly Obese Patients Undergoing Bariatric Surgery
The goal of this study is to elucidate the efficacy and safety of oxelidine combined with oligopiate anesthesia for multi-modal analgesia in weight-loss surgery in morbidly obese patients, and to discover a new strategy for…
- Trial name
- NCT06712199
- Testing
- oxalidine
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Yongtao Sun
Opioid Use, Kidney Diseases
Enhanced Recovery After Surgery in Kidney Transplant Donors
Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques.
- Conditions
- Opioid Use, Kidney Diseases, Pain, Postoperative, Postoperative Complications
- Trial name
- NCT04110080
- Testing
- multimodal pain management, goal directed fluid management, preoperative carbohydrate loading
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Trigeminal Neuralgia
Postoperative Analgesia in Patients With Microvascular Decompression
Perioperative pain is caused by a variety of harmful factors through multiple mechanisms, therefore, reasonable postoperative analgesia should be combined with drugs or measures of different mechanism , which is called multimodal…
- Trial name
- NCT03152955
- Testing
- Ketamine, scalp nerve block, ondansetron
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Pain
Multimodal Pain Management for Cesarean Delivery
Opioid use and abuse has become a major medical problem in the United States. Over prescription of opioid medications is a major contributor to this growing problem.
- Trial name
- NCT02922985
- Testing
- Intravenous acetominophen, Ketorolac, intramuscular, Bupivacaine, subcutaneous
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Opioid Abuse (Disorder), Opioid Analgesia
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
The goal of this clinical trial is to evaluate strategies for optimizing postoperative multimodal pain regimens and reducing opioid dependency in patients undergoing upper extremity surgery.
- Conditions
- Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption
- Trial name
- NCT07750639
- Testing
- Naproxen, Acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Cesarean Section, Postoperative Pain
Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section
The investigators aim to compare the analgesic efficacy of intravenous acetaminophen alone versus combination of acetaminophen/ibuprofen (Maxigesic®IV) in multimodal analgesia after cesarean section.
- Trial name
- NCT06479122
- Testing
- Acetaminophen, Acetaminophen/Ibuprofen
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lumbar Disc Herniation
Cortical Surface Functional Changes After Lever Positioning Manipulation for Lumbar Disc Herniation
Lever positioning manipulation (LPM) is used to treat pain associated with lumbar disc herniation (LDH), but treatment-associated changes in cortical functional organization remain unclear.
- Trial name
- NCT07914842
- Testing
- Lever Positioning Manipulation
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Trauma, Rib Fractures
Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes.
- Conditions
- Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency
- Trial name
- NCT06533904
- Testing
- Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University