Clinical trials: Multimodal Intervention, open to volunteers
Sleep Disturbance in Advanced Cancer
Sleep Well At Night
Research has shown that the incidence of sleep disturbances in people with cancer is much higher than in the general population. Sleep problems can lead to worse symptoms, quality of life, and potentially impact outcomes.
- Trial name
- SWAN (NCT07068971)
- Testing
- Online cognitive behavioural therapy for insomnia, bright light therapy, activity
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Our Lady's Hospice and Care Services
Hepotacellular Carcinoma
Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention
This study is for patients with early-stage liver cancer who are planning to have surgery. The goal of this research is to see if a personalized treatment plan, guided by a computer model (an artificial intelligence tool), can…
- Trial name
- NCT07282184
- Testing
- Neoadjuvant HAIC + Lenvatinib + PD-1 Inhibitor, Curative Liver Resection, Multimodal AI Risk Stratification
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Tongji Hospital
Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis
Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?
The goal of this clinical trial is to learn if a 3-month online pelvic health program works to improve pain and sexual wellbeing in adult women with chronic genital pain.
- Conditions
- Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis, Vestibulodynia, Provoked Vestibulodynia
- Trial name
- PVD (NCT06999395)
- Testing
- Virtual online pelvic health program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Queen's University
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Asthma, Multi Morbidity
LIving BEtteR With asThma studY:: A Multimodal Intervention to Address Multimorbidity in Difficult Asthma
Multimorbidity is a significant issue for many patients with difficult asthma. With patients, we have co-designed a multimodal intervention comprising prescribed exercise, dietary support, breathing pattern retraining and…
- Trial name
- LIBERTY (NCT06513117)
- Testing
- Behaviour change, Dietary support, Breathing pattern retraining
- Volunteers
- 30 people
- Sponsor
- University of Southampton
Paraspinal Muscles, Low Back Pain
Multimodal Exercise Therapy for Non-Surgical Intervention of Nonspecific Low Back Pain.
This multicenter, assessor-blinded, two-arm parallel randomized controlled trial (N = 314) will compare the efficacy and safety of a 6-week multidimensional exercise program plus usual pharmacological care (experimental arm)…
- Conditions
- Paraspinal Muscles, Low Back Pain, Machine Learning, Radiomics
- Trial name
- METNLBP (NCT07353372)
- Testing
- Multidimensional exercise intervention, Oral NSAIDs
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Xuanwu Hospital, Beijing
Endometrial Cancer
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
RESILIENCE is 24-week randomized controlled trial that assesses the efficacy of a digital wellness platform, combined with online support from healthcare professionals, to enhance waist circumference and other vital health…
- Trial name
- RESILIENCE (NCT06038032)
- Testing
- Digital wellness platform, Online healthcare professional support
- Where
- 2 sites in Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Urinary Incontinence
Effects of a Multimodal and Multidimensional Intervention on Urinary Incontinence in Young Nulliparous Female Athletes.
A prevalence of urinary incontinence ranging from 5.7% to 80% has been observed in young nulliparous athletes during their activity. The usual recommendations for managing adult women do not seem to be transferable.
- Trial name
- PELVICATHLE (NCT07644273)
- Testing
- Combined pelvic health education and lumbar-pelvic-abdominal stability strengthening programme., Usual activities
- Where
- France
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
Typical postoperative pain control after minimally invasive hysterectomy includes ibuprofen, acetaminophen, and a short course of narcotics.
- Conditions
- Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified, Adenomyosis of Uterus, Fibroid Uterus
- Trial name
- NCT07664956
- Testing
- Cyclobenzaprine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Christiana Care Health Services
Frailty, Aged
RCT to Analyze the Efficacy of a Spanish Healthcare ministRy Based In InTervention to Reduce Frailty Status in Prefrail Older Adults
Objectives: The main objective is to analyze the efficacy of an intervention based on the algorithm proposed by the Spanish Healtcare Ministry (see figure in annex 1) at Primary Care level to reduce Frailty status or Physical…
- Conditions
- Frailty, Aged, Exercise
- Trial name
- FRAILMERIT (NCT05002439)
- Testing
- Multicomponent physical exercise program and a nutritional intervention
- Where
- Spain
- Volunteers
- 273 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
Ostomy, Sleep Quality
Artificial Intelligence-Supported Nursing Program for Sleep Quality in People With an Ostomy
Individuals living with an intestinal or urinary stoma frequently report disturbed sleep. Night-time pouch filling and leakage, odour and gas concerns, restricted sleeping positions, peristomal skin problems and the need for…
- Conditions
- Ostomy, Sleep Quality, Quality of Life
- Trial name
- AI-MNI (NCT07805226)
- Testing
- AI-MNI: Artificial Intelligence-Supported Multimodal Nursing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Koç University
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Overweight and Obese Adults, Obese Patients (BMI ≥ 30 kg/m²)
Eatit's Obesity Intervention: Effects on Weight, Eating Habits and Health
Obesity is a growing public health problem in Sweden, but access to care varies depending on geographical location. Eatit´s multimodal digitally dietitian-supported lifestyle intervention offers an accessible treatment…
- Trial name
- NCT07183228
- Testing
- Lifestyle Intervention for Obesity
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Eatit AB
Obesity & Overweight
Multimodal Intervention for Weight Management and Health in the Elderly Population
Aging may be accompanied by changes in body composition, muscle strength, metabolic health, and well-being. In older adults with overweight or obesity, strategies that combine physical exercise, behavioral changes, and…
- Trial name
- NCT07820774
- Testing
- Nutritional guidance focused on adopting a high-protein diet., Group Cognitive Behavioral Therapy Intervention, Resistance Training Program
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Cesarean Section Complications, Postpartum Care
Using Empowered Relief and Education To Help Postpartum Women Recover After Cesarean Delivery
The purpose of this study is to study the effect of a pain relief skills session (Empowered Relief) and educational content on global postpartum recovery at 12 weeks post cesarean delivery.
- Trial name
- NCT07192718
- Testing
- Empowered Relief, Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University