Clinical trials: Multimorbidity, Cardiovascular Diseases
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Diabetes Mellitus, Chronic Kidney Diseases
Integrated, Multidisciplinary, Person-centered Care for Patients With Complex Comorbidities: Heart, Kidney and Diabetes
Patient with complex comorbidities present a growing challenge for health-care providers, that the current system is poorly designed to handle.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Chronic Disease
- Trial name
- CareHND (NCT03362983)
- Testing
- CareHND
- Where
- Sweden
- Volunteers
- 131 people
- Sponsor
- Danderyd Hospital
Chronic Heart Failure, Type 2 Diabetes
Prognostic Impact of Diabetes and Weight Variability in Telemonitored Heart Failure
This observational cohort study evaluates the prognostic impact of diabetes, comorbidity burden, and short-term weight variability among adults with chronic heart failure enrolled in a nationwide remote patient monitoring program…
- Conditions
- Chronic Heart Failure, Type 2 Diabetes, Diabetes (DM)
- Trial name
- DM-HF-Tele (NCT07561866)
- Testing
- Diabetes Status, Comorbidity Burden, Weight variability
- Where
- France
- Volunteers
- 16,556 people
- Sponsor
- Satelia
Hypertension, Type 2 Diabetes Mellitus (T2DM)
Community-Empowerment and Environmental Enrichment-based Co-management (CEEEC) Model and Mechanisms for Improving Health of Older Stroke Patients With Multimorbidity
This study is a cluster randomized controlled trial with a 2×2 factorial design conducted in community health centers in Kunshan, Wuhan and Shanghai, China.
- Conditions
- Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity, Stroke
- Trial name
- CEEEC (NCT06975501)
- Testing
- Exercise Intervention, Cognitive Intervention
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Duke Kunshan University
Multimorbidity, Heart Failure
Effectiveness of a Multimodal Intervention With Simulation for Learning Home Health Nursing Care of Patients With Multimorbidity and Heart Failure
The goal of this clinical trial is to evaluate the efficacy of a multimodal intervention with high-fidelity simulations on home health nursing in improving the care of multipathological patients with heart failure in nursing…
- Trial name
- NCT06855719
- Testing
- Training in high-fidelity simulation and knowledge of care protocols in patients with multimorbidity and heart failure
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Stroke
Optimizing Hospital-to-home Transitions for Older Adults With Stroke and Multimorbidity
Stroke is the leading cause of death and adult disability in Canada. Sixty percent of these older adults (> 65 years) will return to their homes after a stroke and will require ongoing rehabilitation.
- Trial name
- NCT04278794
- Testing
- Transitional Care Stroke Intervention (TCSI)
- Where
- 2 sites in Canada
- Volunteers
- 90 people
- Sponsor
- McMaster University
Prescribing Decisions, Diabetes
Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions
The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to…
- Conditions
- Prescribing Decisions, Diabetes, Multimorbidity, Hypertension
- Trial name
- NCT06605807
- Testing
- Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pittsburgh
Statin Treatment for Primary Prevention
STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease
Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older…
- Trial name
- STREAM (NCT05178420)
- Testing
- Statin discontinuation
- Where
- 24 sites in France, Netherlands and 1 more
- Volunteers
- 1,880 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Multimorbidity, Cardiovascular Diseases
Chuvashia Inappropriate Prescribing Study
This is a cross-sectional study based on an outpatient registry. All medical therapy will be registered in order to assess inappropriate prescribing's, in accordance with the criteria PROMPT and BEERS, also in accordance with the…
- Trial name
- CHIP (NCT06845397)
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Hypertension, Diabetes
Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure
The main objective of the study is to compare the effect of two different types of physical exercise modalities on glycated hemoglobin and blood pressure in elderly individuals with multimorbidity.
- Conditions
- Hypertension, Diabetes, Osteoarthritis, Depression Disorders
- Trial name
- NCT06879639
- Testing
- Exercise, Control
- Where
- Portugal
- Volunteers
- 63 people
- Sponsor
- Universidade do Porto
Cardiovascular Diseases
Improving Outcomes in Patients With Cardiovascular Seasonality
Despite a range of evidence-based programs to identify high-risk patients and apply strategies to keep them out of hospital, a growing number of cases are "resistant" to such programs.
- Trial name
- RESILIENCE (NCT04614428)
- Testing
- RESILIENCE Program
- Where
- Australia
- Volunteers
- 203 people
- Sponsor
- Sheila Patel
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypertension (HTN), Type 2 Diabetes
Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation
The purpose of this study is to find out whether a program called HEARTS can improve care for people who have both high blood pressure and diabetes.
- Trial name
- MULTI-HEARTS (NCT07536919)
- Testing
- HEARTS implementation strategies, Supply chain strengthening
- Volunteers
- 1,440 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Hypertension
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic…
- Trial name
- CHRONICLE (NCT05955339)
- Testing
- NOTES, AUDIO
- Where
- 3 sites in United States
- Volunteers
- 1,022 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Heart Failure
Psychosocial Syndemics of Heart Failure
Heart failure (HF) is a common and debilitating chronic disease with a poor prognosis. Many patients with HFhave psychiatric problems such as depression and other medical disorders such as lung or kidney disease.This study will…
- Trial name
- NCT04637776
- Testing
- Hospitalization
- Where
- United States
- Volunteers
- 367 people
- Sponsor
- Washington University School of Medicine
Stroke, Traumatic Brain Injury
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems.
- Conditions
- Stroke, Traumatic Brain Injury, Knee Osteoarthritis, Breast Cancer
- Trial name
- OPTIMA-C (NCT06073106)
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Tan Tock Seng Hospital
Chronic Obstructive Pulmonary Disease, Heart Failure
Multidimensional Approach for COPD and High Complexity
The MACH Study trial will examine the impact on high complexity COPD patients of a multidimensional approach (moderate-intensity physical activity program and clinic-therapeutic re-evaluation of the participants)
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Chronic Disease
- Trial name
- MACH (NCT04986332)
- Testing
- Physical activity program, Global therapeutic remodeling
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Type2Diabetes, Hypertension
Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity
The purpose of this study was to explore the effectiveness of the "Digital Care Community Common Good" program in improving disease control indicators, self-management abilities, depression, and quality of life among patients…
- Conditions
- Type2Diabetes, Hypertension, Dyslipidemia, CKD
- Trial name
- NCT07310849
- Testing
- Digital Care Community Common Good Program, Usual Care
- Where
- Taiwan
- Volunteers
- 169 people
- Sponsor
- Chang Gung University of Science and Technology
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao