Clinical trials: Multimorbidity, open to volunteers
Type2Diabetes, Hypertension
Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity
The purpose of this study was to explore the effectiveness of the "Digital Care Community Common Good" program in improving disease control indicators, self-management abilities, depression, and quality of life among patients…
- Conditions
- Type2Diabetes, Hypertension, Dyslipidemia, CKD
- Trial name
- NCT07310849
- Testing
- Digital Care Community Common Good Program, Usual Care
- Where
- Taiwan
- Volunteers
- 169 people
- Sponsor
- Chang Gung University of Science and Technology
Chronic Disease
Multimorbidity Management Supported by a Digital Platform
This study aims to assess whether the use of the METHIS digital platform using a patient-centered approach contributes to an improvement in the quality of life, mental health and physical activity of patients with multimorbidity…
- Trial name
- NCT05593835
- Testing
- METHIS Platform, Goal-Oriented Care Training Program
- Volunteers
- 1,380 people
- Sponsor
- Universidade Nova de Lisboa
Multimorbidity
Co-design of a Seamless Person-centered Intervention to Optimize Medication Use Across Healthcare Levels
Multiple long term conditions entails various needs for complex medication treatment, which is a huge clinical challenge considering medication interactions and disease-medication interactions.
- Trial name
- CIRCLE (NCT05421143)
- Where
- Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Malin Olsen Syversen
Diabetes Mellitus, Hypertension
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic…
- Trial name
- CHRONICLE (NCT05955339)
- Testing
- NOTES, AUDIO
- Where
- 3 sites in United States
- Volunteers
- 1,022 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Statin Treatment for Primary Prevention
STREAM Trial - Subclinical Atherosclerosis
Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older…
- Trial name
- STREAM-SubATS (NCT05482399)
- Testing
- Statin discontinuation
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Chronic Cardiovascular Disease, Acute Cardiovascular Disease
Chronic and Acute Cardiovascular Diseases in Elderly Intensive Care Patients
Very old patients are a rapidly growing and vulnerable population in acute cardiovascular care but remain underrepresented in clinical trials.
- Conditions
- Chronic Cardiovascular Disease, Acute Cardiovascular Disease, Frailty
- Trial name
- NCT07385482
- Where
- Germany
- Volunteers
- 4,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Transitional Care, Remote Patient Monitoring (RPM)
New Care Pathways for Supporting TRANSitional CARE From Hospital to Home Using AI and Personalized Digital Assistance
The objective of the TRANSCARE study is to evaluate the use of a digital remote monitoring system to reduce the risk of 30-day readmission in multimorbid elderly patients.
- Conditions
- Transitional Care, Remote Patient Monitoring (RPM), Geriatric Multimorbidity
- Trial name
- TRANSCARE (NCT07731126)
- Testing
- TRANSCARE Digital Remote Monitoring Ecosystem
- Where
- 3 sites in Italy, Norway and 1 more
- Volunteers
- 210 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Cardiometabolic Comorbidities
Self-management Intervention for People With Cardiometabolic Multimorbidity: A Pilot Randomized Controlled Trial
This pilot randomized controlled trial aims to evaluate the feasibility and preliminary effects of a telephone-based self-management intervention for adults with cardiometabolic multimorbidity.
- Trial name
- NCT07792785
- Testing
- Motivational interviewing, self-affirmation and problem-solving, Usual Care
- Where
- China
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Multimorbidity
A New Organisation of Clinic for Multimorbidity and Polypharmacy
The purpose of this study is to investigate: 1) the implementation and 2) the effects of an outpatient program for patients with complex multimorbidity.
- Trial name
- NCT06735339
- Testing
- Clinic for Multimorbidity
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Central Jutland Regional Hospital
Multiple Mental Health Conditions, Child Mental Health
Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions
The Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions (CALM) Master Observational Trial is a prospective, longitudinal observational study that seeks to improve clinical care for youth with multiple…
- Conditions
- Multiple Mental Health Conditions, Child Mental Health, Youth Mental Health
- Trial name
- CALM (NCT07699159)
- Where
- 6 sites in Canada
- Volunteers
- 1,620 people
- Sponsor
- Centre for Addiction and Mental Health
Kidney Transplant, Cardiovascular (CV) Risk
Multimorbidity and Cardiovascular Risk Factors After Renal Transplant
Who can participate? Any adults over the age of 18 who have received a kidney transplant at the research centre are eligible for recruitment within the first month after transplant What does the study involve? The study involves…
- Conditions
- Kidney Transplant, Cardiovascular (CV) Risk, Multimorbidity
- Trial name
- MCaRT (NCT07205692)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Exercise, Sedentary Behavior
Association of a Digital Signature of Physical Activity and Sedentary Lifestyle With the Development of Multimorbidities in Chronic Diseases (eMOB)
Physical activity (PA) and sedentary lifestyle are determinants in the development of chronic diseases and associated quality of life alterations.
- Conditions
- Exercise, Sedentary Behavior, Non Communicable Diseases, Comorbidities and Coexisting Conditions
- Trial name
- eMOB (NCT05578495)
- Testing
- Accelerometer data
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Mitigating Chronic Respiratory Disease Through the Lens of Multimorbidity
The investigators aim to evaluate whether it is feasible for healthcare professionals to implement a case-finding tool to identify individuals at high risk for chronic respiratory diseases (CRDs) during routine care for…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Preserved Ratio Impaired Spirometry
- Trial name
- MARES2 (NCT07093021)
- Where
- 2 sites in Brazil
- Volunteers
- 1,000 people
- Sponsor
- University College, London
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Stroke, Hypertension
CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity
CEEEC-II is a 12-week, community-based, prospective extension study conducted in 32 community health service stations in Kunshan, China.
- Conditions
- Stroke, Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity
- Trial name
- CEEEC-II (NCT07778771)
- Testing
- Physical Enrichment, Cognitive Enrichment
- Where
- China
- Volunteers
- 365 people
- Sponsor
- Duke Kunshan University
Multimorbidity
Physical Activity Modifies Exercise Responsiveness
Exercise is the cornerstone of rehabilitation and an essential part of treatment plans for many chronic conditions; however, our understanding of why certain individuals respond positively to exercise while others do not remains…
- Trial name
- NCT07792967
- Testing
- SLIMM - Sit less, interact, move more, PB125
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Multimorbidity
Living With Multimorbidity: Care Coordination and Symptom Management Program (COORDINATE)
The goal of this clinical trial is to learn if a new care program, called the COORDINATE Program, can help older adults with two or more chronic health conditions.
- Trial name
- NCT07157982
- Testing
- COORDINATE Program, Enhanced Usual Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Knee Osteoarthritis, Multimorbidity
Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty
This prospective observational cohort study aims to investigate the association between preoperative multimorbidity burden and functional recovery after primary total knee arthroplasty (TKA) in patients with knee osteoarthritis.
- Trial name
- NCT07882316
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Balikesir Ataturk City Hospital