Clinical trials: Multiple Cancers
Gastric Cancer, Tongue Images
Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms
In this study, the investigators will prospectively recruit 100,000 individuals, including gastric cancer patients who have not undergone any anti-tumor treatment and non-gastric cancer participants.
- Conditions
- Gastric Cancer, Tongue Images, Diagnosis
- Trial name
- NCT06078930
- Testing
- Tongue imaging, tougue coating, saliva, gastric juice, and feces
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang Cancer Hospital
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Gastric Cancer
Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA
To facilitate the early gastric cancer diagnosis, an assay based on assessing large-scale methylation and fragmentation profiles of the plasma cell free (cfDNA) will be developed and validated.
- Trial name
- NCT05668910
- Testing
- whole genomic methylation and fragmentation profile analysis of cfDNA
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Multiple Myeloma
Serum Soluble BCMA as a Non-Invasive Marker in Multiple Myeloma
This prospective study aims to investigate serum soluble B-cell maturation antigen (sBCMA) as a non-invasive marker in patients with multiple myeloma and to compare its levels with healthy controls.
- Trial name
- NCT07855718
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Cord Injuries, Multiple Sclerosis
AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis
The UAB Institute for Arts In Medicine (AIM) is currently implementing an expressive emotional writing pilot project for adults with paralysis caused by neurological conditions such as traumatic head or spinal cord injury.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Transverse Myelitis, Amyotrophic Lateral Sclerosis
- Trial name
- NCT04721717
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pilonidal Disease, Pilonidal Cyst/Fistula
MIPE for Pilonidal Disease
Pilonidal disease often presents as a chronic, relapsing condition. A variety of procedures are used in the management of pilonidal disease, with varying degrees of morbidity, disease-free interval, and long-term success.
- Conditions
- Pilonidal Disease, Pilonidal Cyst/Fistula, Pilonidal Sinus Without Abscess, Pilonidal Cyst Without Abscess
- Trial name
- NCT03772873
- Testing
- minimally invasive pilonidal excision
- Where
- 10 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Male Contraception
Open Label, Dose Escalation, Repeat Dose Study Evaluating YCT-529 in Healthy Males
This is a Phase 1b/2a open-label, dose escalation 3 part-study, 28-day, 90-day or 180 day repeat dose study of YCT-529 in healthy males who have decided to have a vasectomy and are waiting for the procedure and for men who have…
- Trial name
- NCT06542237
- Testing
- YCT-529
- Where
- New Zealand
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- YourChoice Therapeutics, Inc.
Anti-Tumor Drug-Associated Interstitial Pneumonia
Research on Early Diagnosis and Risk Stratification Biomarkers of Anti-Tumor Drug-Associated Interstitial Pneumonia Driven by Multi-Omics Integration
This study aims to construct an early diagnostic biomarker panel and risk stratification model for anti-tumor drug-related ILD through integrative analysis of multi-omics data including genomics, transcriptomics, proteomics, and…
- Trial name
- NCT07190703
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fuzhou University Affiliated Provincial Hospital
Healthy Participants, Breast Cancer
Evaluation of See.d as an Automated Blood Sample Preparator for Multiple Liquid Biopsy Applications
This study aims to evaluate the feasibility of using See.d instrument and SBS slides for preparation of plasma and cytological samples from whole blood.
- Trial name
- NCT06097156
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tethis S.p.A.
Breast Neoplasms, Breast Neoplasm Female
Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery
Background: Mastectomies are traditionally performed under general anesthesia (GA), often with the addition of regional anesthesia for post-operative pain relief.
- Conditions
- Breast Neoplasms, Breast Neoplasm Female, Cancer, Breast, Breast Cancer
- Trial name
- TPVB (NCT05711030)
- Testing
- Thoracic paravertebral block multiple (3) injections, Thoracic paravertebral block single injection
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cancer
SUNRISE Aims to Create a Comprehensive, Engaging, and Sustainable Digital Health Promotion Program That Not Only Addresses Immediate Health Behaviours But Also Instils Lifelong Healthy Habits Among Adolescents. It is a Unique, Digitally Enhanced Program Combining Different Digital Solutions With New
SUNRISE aims to create a comprehensive, engaging, and sustainable digital health promotion program that not only addresses immediate health behaviours but also instills lifelong healthy habits among adolescents.
- Trial name
- SUNRISE_2 (NCT06931847)
- Testing
- SUNRISE program
- Where
- 8 sites in Belgium, Cyprus and 6 more
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Biobizkaia Health Research Institute
Hepatocellular Carcinoma (HCC)
Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study)
Hepatocellular carcinoma (HCC) is often diagnosed at an advanced stage, and early detection is critical for improving patient outcomes. Despite this, reliable non-invasive biomarkers for early-stage HCC are limited.
- Trial name
- CENTINEL (NCT07265271)
- Testing
- Small RNA sequence, Rt-qPCR
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Pancreatic Neoplasms
EUS-guided RFA for Pancreatic Neoplasms
Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. Recently, EUS-guided RFA has become available and the device allows EUS-guided treatment of pancreatic neoplasms.
- Trial name
- NCT03218345
- Testing
- EUS-guided RFA
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Extrahepatic Cholangiocarcinoma
An Observational Real World Study on the Efficacy and Safety of Toripalimab Injection Combined With TACE in the Treatment of Extrahepatic Cholangiocarcinoma
This is an open-label, single-arm, multicenter phase II clinical study to preliminarily observe and evaluate the efficacy and safety of Toripalimab combined with TACE in the treatment of extrahepatic cholangiocarcinoma.
- Trial name
- NCT05448183
- Testing
- Toripalimab, Gemcitabine,Oxaliplatin
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Xuhua Duan
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Sexually Transmitted Diseases, HIV
Effectiveness of HIV Risk Reduction Program Among African American Men
This study will test the effectiveness of a brief clinic-based program designed to promote the correct use of condoms among young African-American men newly diagnosed with a sexually transmitted disease.
- Trial name
- NCT00314028
- Testing
- Focus on the Future, Control standard of care treatment
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Cancer
Multi-Cancer Detection Observational Cohort Study
This study assesses the incorporation of Multi-Cancer Detection (MCD) testing, designed to detect many types of cancer, into clinical practice to understand both its use and effect in real world practice conditions.
- Trial name
- NCT06962995
- Testing
- Blood Sample, Surveys
- Where
- 3 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cancer
Supporting Families In Coping With Parental Cancer: A Multi-Site Randomized Controlled Trial
The goal of this behavioral research study is to learn about the effect of a parent support intervention on cancer patients' and their family caregivers' mental wellbeing, and family functioning.
- Trial name
- NCT07852858
- Testing
- Parent Support Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Weight Loss
Exercise Duration Models, in Middle-aged Men
Duration of exercise is an important factor among the medical guides for weight loss. However, there is still little knowledge about other its models in middle-aged and older men.
- Trial name
- NCT03046641
- Testing
- Continuous training, The interval training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education