Clinical trials: Multiple Chronic Health Conditions
Diabetes Mellitus, Chronic Disease
ECHO for Diabetes and Multiple Chronic Conditions Study
Diabetes mellitus is a chronic condition that affects the body's ability to process sugar effectively, which over time can increase the risk of heart disease, high blood pressure, and kidney damage.
- Trial name
- E4DMMC (NCT06451458)
- Testing
- ECHO program for DMMC, Usual care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of New Mexico
Polypharmacy, Multiple Chronic Conditions
Protocol for a Multi-site Pilot Study of the OptiMed Clinical Trial
Background: Optimal medication management is one of the essential preconditions for polymedicated home-dwelling older adults with multiple chronic conditions to remain at home and preserve their quality of life and autonomy.
- Trial name
- OptiMed (NCT06688591)
- Testing
- Intervention programme to optimise medication management and prevent MRPs
- Volunteers
- healthy volunteers welcome
- Sponsor
- HES-SO Valais-Wallis
Multiple Comorbidity
Telerehabilitation With Multicomponent Exercise for Older Adults With Multiple Chronic Conditions
The goal of this clinical trial is to learn if a multicomponent exercise program delivered through telerehabilitation improves physical fitness and quality of life in older adults with multiple chronic conditions living in…
- Trial name
- TELEREAHB-COL (NCT07299786)
- Testing
- Multicomponent Exercise via Telerehabilitation, Home-Based Physiotherapy
- Where
- Colombia
- Volunteers
- 34 people
- Sponsor
- Fundacion Universitaria Maria Cano
Multiple Chronic Conditions
Patient Priorities Care-North Carolina
The long-term goal of this research is to re-engineer clinical decision-making for older adults with multiple chronic conditions (MCC) to focus on patients' self-identified health priorities.
- Trial name
- PPC-NC (NCT04233554)
- Testing
- Patient Priorities Care
- Where
- 5 sites in United States
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Pain
Group-based Integrative Pain Management (IPMP+ Pilot)
Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment options.
- Trial name
- NCT05906784
- Testing
- group acupuncture, Integrative Group Medical Visits
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Francisco
Cardiovascular, Comorbidity
Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities
This is formative evaluation trial guided by the Values Clarification Theory25 and the Cultural Values Theory26, with specific aims to: Aim 1.
- Conditions
- Cardiovascular, Comorbidity, Diabetes, Inflammatory Joint Diseases
- Trial name
- PPC Heart (NCT07748858)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Alabama at Birmingham
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Multiple Chronic Conditions, Dementia
Patient Priorities Care for Hispanics With Dementia
Most persons living with dementia (PlwD) have multiple chronic conditions (MCC). Managing MCC typically involves adhering to clinical practice guidelines for single diseases.
- Trial name
- PPC-HD (NCT05303194)
- Testing
- Patient Priorities Care (PPC) Approach, Adapted PPC
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Chronic Conditions, Multiple, Old Age; Debility
Brief Physical Activity Intervention for Older People With Multimorbidity
Physical activity is an important determinant of health and well-being in older people. However, many older people do not achieve recommended physical activity levels and increasing older people's physical activity is…
- Conditions
- Chronic Conditions, Multiple, Old Age; Debility, Physical Inactivity
- Trial name
- NCT05287932
- Testing
- Brief physical activity intervention
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Northumbria University
Multiple Chronic Diseases
Impact of Goal-Directed Care Interventions
Abstract The study explores the effects of a goal-directed care intervention on self-efficacy, symptom distress, and quality of life in patients with multiple chronic conditions.
- Trial name
- NCT06752564
- Testing
- Goal-Oriented Care Model, standard health education
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS)
Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.
The goal of this clinical trial is to learn if an online wellness program can lower fatigue and improve mood and quality of life in people with progressive multiple sclerosis who are 45 to 70 years old and are experiencing…
- Trial name
- DEW (NCT07831928)
- Testing
- Online wellness course and online exercise platform, Usual Care Group
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Iowa
Chronic Disease, Multi-morbidity
Minnesota Care Coordination Effectiveness Study
Medical care has improved greatly over the past 50 years. Treatments for most medical conditions can help us lead longer and healthier lives, but there are still problems.
- Conditions
- Chronic Disease, Multi-morbidity, Care Coordination
- Trial name
- MNCARES (NCT04957979)
- Testing
- Nursing/Medical Model of Care Coordination, Medical/Social Model of Care Coordination
- Where
- 3 sites in United States
- Volunteers
- 25,507 people
- Sponsor
- HealthPartners Institute
Caregiver Burnout
Caregiver Support in the Context of Multiple Chronic Conditions
This research is being done to learn whether services to the caregiver to provide emotional, instrumental and social support can improve quality of life and other outcomes.
- Trial name
- NCT04090749
- Testing
- Caregiver-Support
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Kidney Diseases, Chronic Kidney Diseases
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
The overarching goal of this project is to refine and adapt previous work on the NAVIGATE-Kidney project for individuals with CKD.
- Trial name
- NAV-Kidney (NCT06810622)
- Testing
- Community health worker intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of Colorado, Denver
Stroke, Comorbidity
My Stroke Team (MYST): Stroke App Pilot Study
Most stroke survivors live with other chronic health conditions that can negatively affect their recovery and overall health and well-being.
- Conditions
- Stroke, Comorbidity, Chronic Disease
- Trial name
- NCT02230280
- Testing
- Strengthening Community-Based Stroke Care: A Pilot Study of a Community Navigation and Rehabilitation Intervention that Includes a Mobile Health Solution
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Premature Infant Disease, Family Research
PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants
The purpose of this study is to refine and pilot test a mobile health (mHealth), video-based family management program for parents of preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Conditions
- Premature Infant Disease, Family Research, Parent-Child Relations, Self Efficacy
- Trial name
- NCT04638127
- Testing
- PREEMIE PROGRESS, Attention Control
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Chronic Disease of Cardiovascular System, Multiple Chronic Conditions
MOCHA Moving Forward: a CBPR Investigation of Chronic Disease Prevention in Older, Low-income African-American Men
The overall goal of the research is to discover how to reduce chronic disease health disparities among older (ages 35-70) low-income African-American men more effectively.
- Conditions
- Chronic Disease of Cardiovascular System, Multiple Chronic Conditions, Chronic Disease
- Trial name
- NCT03745703
- Testing
- MOCHA
- Where
- 2 sites in United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Myelodysplastic Syndromes, Leukemia Myeloid Acute
A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms
This is a post-authorization, retrospective multicentre observational nationwide study (PAS-OD). It will be conducted by reviewing medical records and database of patients who participated in the validation of the psychometric…
- Conditions
- Myelodysplastic Syndromes, Leukemia Myeloid Acute, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell
- Trial name
- NCT02842229
- Where
- 15 sites in Spain
- Volunteers
- 117 people
- Sponsor
- Celgene
Comorbidity, Depressive Symptoms
Community Assets Supporting Transitions (CAST)
The aim of this study is to test a support program for older adults with symptoms of depression and other chronic health problems after they are discharged home from hospital.
- Trial name
- CAST (NCT03157999)
- Testing
- Intervention group (CAST)
- Where
- 4 sites in Canada
- Volunteers
- 127 people
- Sponsor
- McMaster University