Clinical trials: Multiple Sclerosis Fatigue
Multiple Sclerosis, Relapsing-Remitting, Fatigue
Tenofovir Alafenamide for Treatment of Symptoms and Neuroprotection in Relapsing Remitting Multiple Sclerosis
As the in vivo reservoir of the Epstein-Barr virus, B cells play an important role in the perpetuation of MS disease activity. B cell depletion therapy with medications like ocrelizumab or rituximab have proved very successful in…
- Trial name
- NCT04880577
- Testing
- TENOFOVIR ALAFENAMIDE FUMARATE 25 Mg ORAL TABLET [VEMLIDY]
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
Evaluation of Nutritional Status and Fatigue in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic progressive neurological disease, the leading cause of disability after injury accidents in young adults.
- Trial name
- NUTRISEP (NCT02008669)
- Testing
- Blood sampling, Gustatory sensitivity test using Taste strips, Questionnaires
- Where
- 12 sites in France
- Volunteers
- 360 people
- Sponsor
- Lille Catholic University
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Multiple Sclerosis
Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach
The histaminergic system is phylogenetically one of the oldest parts of the nervous system but it is a relatively recent discovery.
- Trial name
- NCT03266965
- Testing
- Carbidopa, L-Histidine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Miami
Multiple Sclerosis
Effects of Dual-Task Training in People With Multiple Sclerosis
The purpose of this study is to investigate the effects of dual task training on balance, gait, dual-task performance, cognitive function, fatigue and functional mobility in people with Multiple Sclerosis(MS).
- Trial name
- NCT05526287
- Testing
- Dual-Task Training, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ege University
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
Sexual Dysfunction in Women With Multiple Sclerosis (MS)
Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Fatigue in Multiple Sclerosis, Sexual Disfunction
- Trial name
- MS (NCT07193823)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ege University
Multiple Sclerosis
Efficacy Study of "Imaginative Distention", a Self Managed Tool to Cope With Fatigue,Insomnia and Stress in pw Insomnia and pw MS
Imaginative Distention (ID) is proposed as supportive and integrative intervention to cope with fatigue, (principal end point), to cope with insomnia, stress perception and to improve QoL of pw MS, insomnia pw and health care…
- Trial name
- DIMMISI (NCT02290990)
- Testing
- "Imaginative Distention" technique
- Where
- Italy
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Niguarda Hospital
Multiple Sclerosis (MS), Fatigue
Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients…
- Conditions
- Multiple Sclerosis (MS), Fatigue, Physical Inactivity
- Trial name
- NCT06270641
- Testing
- ExerciseRx intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Washington
Multiple Sclerosis
Combined Exercise Training in Patients With Multiple Sclerosis
It is stated that the affected cognitive functions in Multiple Sclerosis are learning, memory, attention, speed of information processing, visuospatial skills, and executive functions.
- Trial name
- NCT03591809
- Testing
- combined exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Gazi University
Multiple Sclerosis
Clinical Factors Associated With Position Sense in Patients With Multiple Sclerosis
Sensory impairment is an important problem for patients with Multiple Sclerosis (MS). Although there is no complete loss of sensation in patients, 80% of patients have a significant sensory impairment.
- Trial name
- NCT04548297
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis
Fighting Fatigue in Multiple Sclerosis: TMS vs. tDCS Efficacy.
Multiple Sclerosis (MS) is a chronic neurological disease impacting 2.8 million individuals globally, with fatigue being its most debilitating symptom, reported by 75% of patients.
- Trial name
- NIBS_MSf (NCT07842302)
- Testing
- TMS, tDCS
- Volunteers
- 80 people
- Sponsor
- Universitat Oberta de Catalunya
Multiple Sclerosis
Home Exercise Telerehabiliation for MS
The primary purpose of this study is to evaluate the effects of an individualized telerehabilitation program on mobility, fatigue, and quality of life for Veterans with MS.
- Trial name
- NCT03655431
- Testing
- Telerehabilitation, Standard treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shane.Chanpimol
Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis
Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple Sclerosis
The goal of this clinical trial is to learn whether a structured lifestyle program can improve health and wellbeing in people living with multiple sclerosis (MS).
- Trial name
- HEAL-MS (NCT07589062)
- Testing
- Multi-Domain Lifestyle Intervention
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- New York University Abu Dhabi
Relapsing-Remitting Multiple Sclerosis
Effects of Electromechanical Gait Trainer in Patients With Multiple Sclerosis
Multiple Sclerosis is a very disabling disorder in young adult patients leading to an important limitation in daily life activities and social participation.
- Trial name
- NCT01564511
- Testing
- Gait trainer treatment, Conventional treatment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Universita di Verona
Gait Balance, Balance
Effects of Lower Extremity Neuromuscular Facilitation and Patients With Multiple Sclerosis
Objective: This study aimed to investigate the effects of lower extremity Proprioceptive Neuromuscular Facilitation (PNF) exercises on balance, gait, and fatigue in patients with Multiple Sclerosis (MS).
- Conditions
- Gait Balance, Balance, Fatigue Syndrome, Chronic
- Trial name
- NCT07263854
- Testing
- exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sanko University
Multiple Sclerosis
Cognitive Functions in Patients With Multiple Sclerosis
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients.
- Trial name
- NCT03594357
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis
Investigating the Impact of Sex Hormones in Multiple Sclerosis
Emerging evidence indicates that females with MS experience worsened symptoms during the luteal phase (post ovulation) of the menstrual cycle when progesterone levels rise and estradiol fluctuate.
- Trial name
- NCT07081594
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Milap Sandhu
Multiple Sclerosis (MS) Relapsing Remitting
Effect of Probiotics on Relapsing-Remitting Multiple Sclerosis
This study aimed to assess the effect of probiotic supplementation on fatigue, quality of life, disability, depression and inflammatory markers in patients with relapsing-remitting multiple sclerosis (RRMS).
- Trial name
- PRO-RRMS (NCT07346924)
- Testing
- Probiotic dietary supplement, Standard medical treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Multiple Sclerosis, Fatigue
High-intensity Resistance Training in People With Multiple Sclerosis Experiencing Fatigue
Fatigue is one of the most frequently reported and disabling impairments in multiple sclerosis (MS) and is associated with activity limitations, participation restrictions and reduced health-related quality of life (HRQL).MS…
- Conditions
- Multiple Sclerosis, Fatigue, Exercise Therapy, Resistance Training
- Trial name
- NCT04562376
- Testing
- High-intensity resistance training, Low frequency of high-intensity resistance training
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Karolinska Institutet
Multiple Sclerosis
The Effect of Acupressure on Multiple Sclerosis Patients
There are studies in the literature evaluating the effects of acupressure application in MS patients. In a study; it was shown that acupressure application reduced pain and fatigue.
- Trial name
- MS (NCT07558252)
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hasan Kalyoncu University