Clinical trials: Multiple Trauma/Injuries
Sports Physical Therapy, Multi-Tasking Behavior
A New Dual Task Test Method for Football Players
Multitasking (Dual Task) is a measurement method to evaluate cognitive ability to execute multiple functions at the same time. To perform this test, while participant/patient performing a main skill (for example, walking), a…
- Conditions
- Sports Physical Therapy, Multi-Tasking Behavior, ACL Injury, Kinesiophobia
- Trial name
- NCT05218993
- Testing
- A new dual-task measurement method with images, A new dual-task measurement method with cards
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Labrum Injury of the Hip Joint
Research on Acetabular Labrum Injury Based on MR: Multi-angle Deep Learning Model
The purpose of this study is to study the MRI images of acetabular labrum injury by deep learning method, and try to establish a combination model of axial and coronal serial images, and compare with the diagnostic accuracy of…
- Trial name
- NCT04950036
- Testing
- Diagnostic Test
- Where
- China
- Volunteers
- 1,261 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Spinal Cord Injury, Cerebral Palsy
Experimental Evaluation of Wheelchair-Mounted Robotic Arms
Researchers from the University of South Florida's Rehabilitation Engineering program are looking for volunteers to participate in a research study for experimental evaluation of wheelchair-mounted robotic arms (WMRAs).
- Conditions
- Spinal Cord Injury, Cerebral Palsy, Multiple Sclerosis
- Trial name
- HRI (NCT01652352)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Rib; Fracture
RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures
This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic…
- Trial name
- NCT05146986
- Testing
- Non surgical and Surgical
- Where
- 5 sites in Australia, South Korea
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Ischemia-reperfusion Injury
A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants
This is a randomized, double-blind, placebo-controlled, single and multiple ascending dose, Phase 1 study to evaluate the safety, tolerability, and pharmacokinetics of BX-001N after intravenous administration in approximately 64…
- Trial name
- NCT06097702
- Testing
- BX-001N Part 1, BX-001N Part 2
- Where
- Australia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bilix Co.,Ltd.
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
The MESO7 study is a prospective observational research project designed to investigate the mechanisms of resilience and neurodegeneration in neurological diseases and healthy aging.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
- Trial name
- MESO7 (NCT07202494)
- Testing
- Imaging Techniques (MRI 3T & 7T, Functional, Structural, and Metabolic Imaging)
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect…
- Conditions
- Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
- Trial name
- NCT06841198
- Testing
- spinal cord transcutaneous stimulation, Ice testing
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate…
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06579963)
- Testing
- Cool roof
- Where
- 4 sites in Burkina Faso, India and 2 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Upper Limb Function, Upper Limb Pain
Upper Limb Functional Index
To translate and validate the Upper Limb Functional Index into Albanian for use in the Albanian-speaking population.
- Conditions
- Upper Limb Function, Upper Limb Pain, Upper Limb; Injury, Superficial, Multiple, Upper Limb Rehabilitation
- Trial name
- ULFI-A (NCT06834919)
- Testing
- Observational
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Anterior Cruciate Ligament Injuries
Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04464330
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Trauma
The WikiTrauma Interrupted Time Series Protocol
The purpose of this study is to study the combined effect of WikiTrauma, a free collaborative database of clinical decision support tools, and Wiki101, a training course teaching participants how to use WikiTrauma, on the quality…
- Trial name
- WikiTrauma (NCT04035772)
- Testing
- Wiki101 and WikiTrauma
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laval University
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Pressure Ulcers Stage II, Pressure Ulcers Stage III
Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries
Pressure injuries, commonly known as pressure ulcers, affect over 2.5 million people in the United States. Pressure injuries are classified into four escalating stages, from intact skin to full thickness wounds with deep tissue…
- Conditions
- Pressure Ulcers Stage II, Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
- Trial name
- NCT05496296
- Testing
- Altrazeal® Transforming Powder Dressing
- Where
- 14 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Concussion
Cortical Plasticity Assessment in Athletes With a History of Concussion
The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used as reliable neurophysiological marker of…
- Trial name
- NCT01112761
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Epilepsy, Migraine
Clinical Applications of High-Frequency Oscillations
The objective of this study is to utilize high-frequency brain signals (HFBS) to localize functional brain areas and characterize HFBS in epilepsy, migraine, and other brain disorders.
- Conditions
- Epilepsy, Migraine, Headache, Pain
- Trial name
- HFOs (NCT00600717)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Complete Spinal Cord Injury, Incomplete Spinal Cord Injury
Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training
The purpose of this study is to develop an algorithmic-based evaluation and treatment approach for wearable robotic exoskeleton (WRE) gait training for patients with neurological conditions.
- Conditions
- Complete Spinal Cord Injury, Incomplete Spinal Cord Injury, Acquired Brain Injury, Multiple Sclerosis
- Trial name
- NCT03057652
- Testing
- ReWalk, EKSO, REX
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Multiple Trauma
Danger Response in Polytrauma Patients
The NTF_PT_2014 multicenter study aims to collect, store, and analyse plasma and serum from polytrauma-patients (injury severity score ≥25) and corresponding clinical data to address 1) how trauma modulates the release of danger…
- Trial name
- NTF-PT (NCT02682550)
- Testing
- blood drawing
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Trauma, Rib Fractures
Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes.
- Conditions
- Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency
- Trial name
- NCT06533904
- Testing
- Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Anterior Cruciate Ligament Injuries
Spatiotemporal Characteristics and Multi-body Dynamics Modeling Information After ACL Rupture and Reconstruction
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04462432
- Testing
- no intervention
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital