Clinical trials: Multiple Trauma/Injuries
Pressure Ulcer, Pressure Injury
What is the Incidence of Pressure Ulcer Category II-IV (Including Deep-tissue Injury and Unstageable) on a Static Air Foam Hybrid Mattress?
Pressure ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Bed Sore
- Trial name
- NCT05142878
- Testing
- Ultracore Repose® mattress
- Where
- 5 sites in Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Neurologic Disorder, Parkinson Disease
High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive.
- Conditions
- Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida
- Trial name
- SHIFT-AR (NCT05951985)
- Testing
- HIFT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Bimalleolar Ankle Fractures
CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures
The OL1000 is intended to be used as a non-invasive adjunctive treatment for adult males or females that have sustained a closed, unstable ankle fracture that requires surgical treatment for stabilization.
- Trial name
- NCT02688855
- Testing
- Active Combined Magnetic Field OL1000 Bone Growth Stimulator
- Where
- 9 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Encore Medical, L.P.
Distal Radius Fracture, Multiple Trauma
Dynamic External Fixation in Treatment Distal Radius Fractures - Elderly Patients
A single center, parallel group, prospective, randomized clinical trial was conducted at the department of Hand Surgery, ABC (Andre, Bernardo, Caetano) Foundation University Hospital, Santo Andre, Brazil.
- Conditions
- Distal Radius Fracture, Multiple Trauma, Elderly Person Maltreatment
- Trial name
- NCT03154424
- Testing
- External fixation in treatment the distal radius fracture
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
Acute Kidney Injury
Acute Kidney Injury in Pediatric Polytrauma Patients at Assiut University Trauma Unit: A Cross-Sectional Study on Incidence and Predictive Risk Factors
This study aims to investigate the true incidence and clinical presentation of post-traumatic AKI in hospitalized pediatric patients and identify the risk, and severity of AKI.
- Trial name
- NCT06177886
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spasticity, Multiple Sclerosis, Stroke, Trauma
Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity
Spasticity - movement disorder, which is part of the syndrome of defeat top motor-neuron, characterized by the rate-dependent increase in muscle tone and increased dry-core reflections from hyperexcitability of stretch receptors…
- Trial name
- ANTMS (NCT01786005)
- Testing
- Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Rotator Cuff Tears
BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears
This study aims to evaluate the safety and effectiveness of arthroscopic rotator cuff repair augmented with the BioBrace® Implant vs.
- Trial name
- REinForce (NCT05997381)
- Testing
- Arthroscopic rotator cuff repair with BioBrace® Implant augmentation., Arthroscopic rotator cuff repair
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- CONMED Corporation
Peripheral Vascular Disease
A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery
OSPREY is a multi-center, single arm, non-randomized, prospective clinical trial. Subjects will undergo a superficial femoral artery (SFA) stent procedure using the Misago™ Peripheral Self Expanding stent once all of the…
- Trial name
- OSPREY (NCT01118117)
- Testing
- Misago™ Self-Expanding Stent System
- Where
- 31 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Terumo Medical Corporation
Multiple Sclerosis, Stroke
An Assistive Powered Wheelchair: Stage 2 Trial
Preliminary evaluation of an obstacle alerting system to enhance the user's independent mobility by improving their confidence to drive and their safety in driving a powered wheelchair.
- Conditions
- Multiple Sclerosis, Stroke, Cystic Fibrosis, Motor Neurone Disease
- Trial name
- EDUCAT (NCT05292690)
- Testing
- Powered Wheelchair Obstacle Alerting System
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Fracture, Bone Fracture
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Fracture, Bone Fracture, Dislocation, Fracture Multiple
- Trial name
- FRACT-AI (NCT06130397)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Finger Injuries
Reconstructive of Multiple-digit Soft-tissue Defects Using Regional Dorsal Digital Flaps
Reconstruction of soft-tissue defects in multiple digits poses a significant challenge. This article reports simultaneous reconstruction of multiple small-to-moderate soft-tissue defects using regional dorsal digital island flaps…
- Trial name
- NCT03717220
- Testing
- flap transferring
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Chronic Pain
Pain, Psychiatric Disorders, and Disability Among Veterans With and Without Polytrauma
We believe information to be obtained from this proposed study will prove critical for planning future VA healthcare strategies and developing effective and efficient treatments targeting pain and emotional adjustment…
- Trial name
- NCT00645970
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Hip Fractures
Fragility Fracture Integrated Rehabilitation Management (FIRM)
A number of studies for clinical pathway (CP) after hip fracture have been suggested to improve post-fracture outcome. However, CP is not carried out properly in most countries due to inadequate system and awareness, and lack of…
- Trial name
- FIRM (NCT03430193)
- Testing
- FIRM, Conventional rehabilitation
- Where
- South Korea
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Traumatic Brain Injury, Multiple Trauma
Evolution of Oropharyngeal and Rectal Microbiota After Severe Traumatic Brain Injury
Modifications of the human gut microbiota have been associated with different pathological conditions such as obesity, inflammatory bowel diseases and neurodegenerative diseases.
- Trial name
- BBAX (NCT03965611)
- Testing
- Oropharyngeal swab, Rectal swab, Disability rating scale (DRS-F)
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pressure Ulcer, Pressure Injury
Comparison of Static Air Support Devices (Repose®) and Alternating-Pressure Devices in the Prevention of Pressure Ulcers
Maintaining and improving skin health are major goals in acute and long-term care. Patients at the extremes of age, the critically ill, medically compromised and those with immobility are at risk for developing several skin…
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Bed Sore
- Trial name
- NCT03597750
- Testing
- Repose®
- Where
- 26 sites in Belgium
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University Ghent
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Rotator Cuff Tear, Rotator Cuff Tendinitis
Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of…
- Trial name
- NCT03752827
- Testing
- Adipose Derived Regenerative Cells, Corticosteroid
- Where
- 14 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Burns
A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings
The purpose of this research study is to compare the rate of healing, the infection or complication rate, pain perception and scarring from burn injuries using two types of burn dressings.
- Trial name
- NCT01067729
- Testing
- AWBAT Wound Dressing, AWBAT™, Biobrane®
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aubrey Inc.