Clinical trials: Multiple Trauma/Injuries
Acute Kidney Injury Following Cardiac Surgery
A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.
This was a randomized, multi-centric, placebo-controlled, participant and investigator-blinded study to evaluate the safety, tolerability and efficacy of TIN816 in adult patients at risk for acute kidney injury following cardiac…
- Trial name
- NCT05524051
- Testing
- TIN816
- Where
- 37 sites in United States, Argentina and 13 more
- Volunteers
- 102 people
- Sponsor
- Novartis Pharmaceuticals
Thorax Traumas
Evaluation of Patient Analgesia After Bloc Serratus
Thorax traumas are very common in severe traumatology, including road accidents, representing the second most frequent site (after head injury, according to the FIRST study).
- Trial name
- TraumaThorax (NCT04123977)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Critical Illness, Multi Organ Failure
Parathyroid Hormone Kinetics During CRRT
The objective of this study is to assess the parathyroid hormone serum concentrations and kinetics in critically ill patients admitted to the intensive care unit due to multi-organ failure and undergoing citrate anticoagulation…
- Conditions
- Critical Illness, Multi Organ Failure, Renal Failure, Circulatory Failure
- Trial name
- NCT03873675
- Testing
- parathyroid hormone
- Where
- 3 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu
Rotator Cuff Injuries
A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear
Rotator cuff tear is one of the most common shoulder diseases and retears occur frequently after arthroscopic repair. Therefore, there is a growing need of new therapy to improve structural outcome.
- Trial name
- NCT03668028
- Testing
- TPX-114, Arthroscopic surgery
- Where
- 2 sites in South Korea
- Volunteers
- 93 people
- Sponsor
- Tego Science, Inc.
Wound Infection, Surgical Site Infection
Prophylactic Closed Incision Negative Pressure Wound Therapy on Abdominal Wounds - Clinical and Economic Perspectives
This study evaluates whether specialist negative pressure dressings reduce the risk of wound infections after operations when compared to conservative dressings, and if one negative pressure dressings works better than another.
- Conditions
- Wound Infection, Surgical Site Infection, Surgical Wound, Surgical Incision
- Trial name
- ProNounCE (NCT04110353)
- Testing
- Wound dressings: Conservative dressings, Wound dressings: Prevena dressings, Wound dressings: ciVAC dressings
- Sponsor
- Imperial College London
Disability Physical, Brain Injuries
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna's Rehabilitation Engineering Center of Excellence (REC) is continually developing custom devices for persons with disabilities.
- Conditions
- Disability Physical, Brain Injuries, Stroke, Spinal Cord Injuries
- Trial name
- NCT03567239
- Testing
- Using adaptive device.
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Madonna Rehabilitation Hospital
Pelvic, Acetabular, Femur, or Diaphyseal Tibial Operative Orthopaedic Injuries
Patient-Specific Precision Injury Signatures in Multiply Injured Orthopaedic Patients
The purpose of this study is to evaluate the use of precision methods that quantify injury and response to injury to predict how short-term clinical outcomes are affected by initial and staged orthopaedic interventions in…
- Trial name
- PRECISE (NCT03772730)
- Where
- 8 sites in United States
- Volunteers
- 320 people
- Sponsor
- Major Extremity Trauma Research Consortium
Multiple Trauma/Injuries
A Multi-center Clinical Study on the Status of Trauma Evaluating Ability in Patients With Multiple Trauma
Trauma is a major medical and public health problem facing all countries in the world today. Trauma is the leading cause of death worldwide for people under 45 years of age, and more than 5 million people die each year from…
- Trial name
- NCT03791333
- Testing
- injury severity score
- Volunteers
- 3,600 people
- Sponsor
- Peking University People's Hospital
Acute Spinal Cord Injury
Acute Safety, Tolerability, Feasibility and Pharmacokinetics of Intrath. Administered ATI355 in Patients With Acute SCI
This study will evaluate the acute safety, tolerability, feasibility and pharmacokinetics of 6 dose regimens of ATI355 in acute spinal cord injury patients
- Trial name
- NCT00406016
- Testing
- ATI355
- Where
- 14 sites in Canada, Germany and 1 more
- Volunteers
- 52 people
- Sponsor
- Novartis
Fracture; Rib, Multiple
Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture Ribs
Determine the effect of using oral pregabalin on the analgesic effects of IV infusion of morphine in patients with multiple fracture ribs.
- Trial name
- NCT03473093
- Testing
- Pregabalin 150mg, Morphine
- Volunteers
- 80 people
- Sponsor
- Assiut University
Spinal Cord Injuries, Multiple Sclerosis
A Wheelchair Propulsion Training Program
The overall purpose of this project is to test the feasibility of a manual wheelchair propulsion program which aims to reduce the chance of development of upper limbs pain and injury.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Amputation, Spina Bifida
- Trial name
- HS (NCT04009187)
- Testing
- In-person wheelchair propulsion training program, 30-minute education session
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injuries
A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury
The overall objective of this project is to investigate the effectiveness of daily acute intermittent hypoxia therapy (dAIH), coupled with massed practice training, to improve upper-extremity function in individuals with chronic…
- Trial name
- HANDS (NCT03644277)
- Testing
- Acute Intermitted Hypoxia, Massed Practise, Rapael Glove
- Where
- 3 sites in United States
- Volunteers
- 121 people
- Sponsor
- Shirley Ryan AbilityLab
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
The MESO7 study is a prospective observational research project designed to investigate the mechanisms of resilience and neurodegeneration in neurological diseases and healthy aging.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
- Trial name
- MESO7 (NCT07202494)
- Testing
- Imaging Techniques (MRI 3T & 7T, Functional, Structural, and Metabolic Imaging)
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Overweight, Obese
Obesity/Overweight in Persons With Early and Chronic Spinal Cord Injury (SCI)
The purpose of this study is to determine how exercise and nutritional guidance and supplementation affects your physical fitness, risk for heart disease, your body's ability to burn fat, and your opinions about your health.
- Conditions
- Overweight, Obese, Spinal Cord Injury
- Trial name
- NCT01467817
- Testing
- Lifestyle Intervention, Exercise Control
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Miami
Peripheral Vascular Disease
A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery
OSPREY is a multi-center, single arm, non-randomized, prospective clinical trial. Subjects will undergo a superficial femoral artery (SFA) stent procedure using the Misago™ Peripheral Self Expanding stent once all of the…
- Trial name
- OSPREY (NCT01118117)
- Testing
- Misago™ Self-Expanding Stent System
- Where
- 31 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Terumo Medical Corporation
ALS, Amyotrophic Lateral Sclerosis
NYSCF Scientific Discovery Biobank
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells…
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset
- Trial name
- NCT06203106
- Testing
- Biological Sample Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- New York Stem Cell Foundation Research Institute
Fluid Overload, Hemodynamic Instability
Hemodynamic Effects of Variations in Net Ultrafiltration Rate During Continuous Renal Replacement Therapy.
Net ultra filtration (NUF) is one of the most important parameters during renal replacement therapy (RRT) whose role is to control fluid balance by water removal.
- Trial name
- NEPTUNE (NCT06071026)
- Testing
- Net Ultra Filtration Rate
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study
This longitudinal cohort study aims to detect the topographical nature of the white matter microstructure and resting state functional connectivity patterns across the whole brain in the evolution of pathology as a function of…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Affective and Somatic Complaints, Cognitive Impairments
- Trial name
- NCT02868684
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.