Clinical trials: Muscle Composition
Obesity
Body Composition Outcomes in MS Patients
Objectives The objective of this project is to generate pilot data substantiating our hypothesis that advanced body composition measurement tools will provide more accurate and clinically relevant data on the outcomes of…
- Trial name
- BCOMS (NCT07530718)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Pennington Biomedical Research Center
Liver Cirrhosis
Lean Mass Evaluation of Cirrhotic Patients With Ascites With the Use DXA
Malnutrition due to liver disease is common, however, their detection is difficult. The parameters used for nutritional assessment in clinical practice have limited use in this patient population.
- Trial name
- BCECPA (NCT02421848)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Systemic Inflammatory Response Syndrome
The Effect of Protein and Resistance Training on Muscle Mass in Acutely Ill Old Medical Patients
The purpose of this study is to determine the effect of a high-protein diet during hospitalization in combination with resistance training and a daily protein and energy supplement three months after discharge on the muscle mass…
- Trial name
- NCT02077491
- Testing
- High-protein diet and resistance training
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Hvidovre University Hospital
Critical Illness, Muscle Weakness
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
The rapid decline of muscle mass and function in mechanically ventilated critically ill patients is associated with prolonged length of mechanical ventilation, prolonged intensive care (ICU) and hospital stay, increased ICU and…
- Trial name
- HMB-ICU-CH (NCT03628365)
- Testing
- HMB (beta-hydroxy beta-methylbutyrate)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Mette M Berger
Strength, Body Composition
Omega-3 Fatty Acid Supplementation to Enhance Performance
The goal of this intervention study is to determine if omega-3 fatty acid supplementation as compared to placebo improves performance in track and field athletes. The main questions it aims to answer are: 1.
- Conditions
- Strength, Body Composition, Muscle Soreness
- Trial name
- FO n-3 (NCT05924139)
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Baylor University
Growth Hormone Deficiency, Idiopathic Short Stature
Skeletal Muscle Effects of GH in Boys
The purpose of the study is to measure the functional effects of recombinant GH in skeletal muscle, in addition to growth promotion, in short prepubertal boys with either growth hormone deficiency or idiopathic short stature.
- Trial name
- NCT04020913
- Testing
- Somatropin injection
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Pancreatic Cancer
Impact of Hypertrophy-oriented Resistance Training on Muscle Mass and Quality of Life in Patients With Unresectable Pancreatic Cancer
To determine the efficacy of a 12-week supervised, hypertrophy-oriented strength training program in preserving skeletal muscle mass, physical function, and quality of life in patients with unresectable pancreatic cancer compared…
- Trial name
- HY-PANC (NCT07470268)
- Testing
- supervised, hypertrophy-oriented strength training program
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Europea de Madrid
Colon Cancer
NIMA-Colon Cancer Study
The goal of this study is to evaluate the effects of nutritional supplementation and physical activity interventions on recovery, muscle strength, nutritional status, inflammation, and metabolic health in adults with colon cancer…
- Trial name
- NIMA (NCT07534852)
- Testing
- Standard hypercaloric-hyperproteic nutritional supplementation, HMB-enriched hypercaloric-hyperproteic nutritional supplementation with vitamin D and calcium, Supervised exercise program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Aging, Healthy Aging
Eating Habits and Lifestyle Profile of an Italian Aging Cohort
Aging is characterized by low-grade inflammatory state, supported by impairment oxidative balance and endocrine changes, leading to changes in: body composition, such as decrease in lean body mass and increase in adipose tissue…
- Conditions
- Aging, Healthy Aging, Life Style, Eating Habit
- Trial name
- NCT04401930
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Body Weight
Lean Body Mass Response to Higher-protein Diets During Winter Military Training
The objectives of this study are to: 1) determine effects of a prototype recovery food product providing supplemental energy on whole-body protein balance, skeletal muscle mass, and biomarkers of physiological status and strain…
- Trial name
- NCT02327208
- Testing
- Control, Protein, Carbohydrate
- Where
- 3 sites in United States, Norway
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Endovascular Aneurysm Repair (EVAR)
Evaluating the Impact of Psoas Muscle Size, Composition, and Clinical Frailty on Long-term Outcomes Following Elective Endovascular Aneurysm Repair
Sarcopenia, which is characterized by the progressive loss of skeletal muscle mass and strength, has emerged as a significant prognostic biomarker in the field of vascular surgery, particularly regarding endovascular aneurysm…
- Trial name
- NCT06864247
- Testing
- No Intervention: Observational Cohort
- Where
- Taiwan
- Volunteers
- 525 people
- Sponsor
- National Taiwan University Hospital
Head and Neck Neoplasms, Dual-Energy X-Ray Absorptiometry
Total Body Composition in Detection of Nutrition Depletion in Head and Neck Patients
The purpose of this study is to define the role of total body composition in the guidance of nutritional support and treatment monitoring in head and neck patients.
- Conditions
- Head and Neck Neoplasms, Dual-Energy X-Ray Absorptiometry, Malnutrition
- Trial name
- TBCHNC (NCT02854735)
- Testing
- Imaging by CT and densitometry
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Multiple Sclerosis, Diet Therapy
Investigation of the Effect of the MIND Diet on Disease Symptoms in Patients With MS
The planned parallel group, randomized controlled study design will be used to determine the effects of the MIND diet applied to MS patients on fatigue, quality of life, technological function and brain fog and to contribute to…
- Conditions
- Multiple Sclerosis, Diet Therapy, Body Composition, Randomised Controlled Trial
- Trial name
- MS (NCT07057999)
- Testing
- MIND Diet (Mediterranean-DASH Intervention for Neurodegenerative Delay), Traditional healthy nutrition program specific to Turkey
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Betul Uner
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Inflammatory Markers, Body Composition, Muscle Strength and Thickness
Aging generates immune, muscular and functional changes. In the pre-frail elderly these changes may be increased and, therefore, preventive interventions are indicated to minimize the consequences of sarcopenia in this…
- Trial name
- NCT03689322
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Vitamin D 25-Hydroxylase Deficiency, Vitamin D Deficiency/Insufficiency
Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes
This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes.
- Trial name
- NCT07641075
- Testing
- Vitamin D supplementation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy
The ULTRA Study: Cross-Comparison of Ultrasound Systems
The purpose of this study is to develop computational methods for cross-comparison of muscle composition measurements in three laboratory ultrasound systems.
- Trial name
- ULTRA (NCT02920619)
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Frail Elderly Syndrome, Sarcopenia
Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is…
- Conditions
- Frail Elderly Syndrome, Sarcopenia, Physical Activity
- Trial name
- EXERNETElder (NCT03831841)
- Testing
- Multicomponent exercise programe
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Skeletal Muscle Energy Metabolism
The Effect of Omega-3 Fatty Acid Supplementation on Skeletal Muscle Membrane Composition and Cellular Metabolism
The biological membranes that surround a cell and its organelles are vital to the overall function of the cell. Fatty acids are the main structural component of membranes, and the presence of specific fatty acids can alter a…
- Trial name
- NCT01732003
- Testing
- Omega-3 Complete
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Guelph